| Turmeric and its major compound curcumin on health: bioactive effects and safety profiles for food, pharmaceutical, biotechnological and medicinal applications J Sharifi-Rad, YE Rayess, AA Rizk, C Sadaka, R Zgheib, W Zam, S Sestito, ... Frontiers in pharmacology 11, 01021, 2020 | 553 | 2020 |
| Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment J Sharifi-Rad, C Quispe, M Butnariu, LS Rotariu, O Sytar, S Sestito, ... Cancer Cell International 21 (1), 318, 2021 | 179 | 2021 |
| Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells S Daniele, B Costa, E Zappelli, E Da Pozzo, S Sestito, G Nesi, ... Scientific reports 5 (1), 9956, 2015 | 105 | 2015 |
| ACE2 in the era of SARS-CoV-2: controversies and novel perspectives F Saponaro, G Rutigliano, S Sestito, L Bandini, B Storti, R Bizzarri, ... Frontiers in Molecular Biosciences 7, 588618, 2020 | 104 | 2020 |
| Oxidative stress, mitochondrial abnormalities and proteins deposition: multitarget approaches in Alzheimer's disease G Nesi, S Sestito, M Digiacomo, S Rapposelli Current topics in medicinal chemistry 17 (27), 3062-3079, 2017 | 97 | 2017 |
| Neffe-Skoci nska, K J Sharifi-Rad, YE Rayess, AA Rizk, C Sadaka, R Zgheib, W Zam, S Sestito, ... Zieli nska, D, 1-23, 2020 | 84 | 2020 |
| Selective thyroid hormone receptor-beta (TRβ) agonists: New perspectives for the treatment of metabolic and neurodegenerative disorders F Saponaro, S Sestito, M Runfola, S Rapposelli, G Chiellini Frontiers in Medicine 7, 331, 2020 | 79 | 2020 |
| Epibatidine: a promising natural alkaloid in health B Salehi, S Sestito, S Rapposelli, G Peron, D Calina, M Sharifi-Rad, ... Biomolecules 9 (1), 6, 2018 | 74 | 2018 |
| Discovery of novel rivastigmine-hydroxycinnamic acid hybrids as multi-targeted agents for Alzheimer's disease Z Chen, M Digiacomo, Y Tu, Q Gu, S Wang, X Yang, J Chu, Q Chen, ... European Journal of Medicinal Chemistry 125, 784-792, 2017 | 69 | 2017 |
| Areca catechu—From farm to food and biomedical applications B Salehi, DA Konovalov, P Fru, P Kapewangolo, G Peron, MS Ksenija, ... Phytotherapy Research 34 (9), 2140-2158, 2020 | 63 | 2020 |
| Memantine prodrug as a new agent for Alzheimer’s Disease S Sestito, S Daniele, D Pietrobono, V Citi, L Bellusci, G Chiellini, ... Scientific reports 9 (1), 4612, 2019 | 62 | 2019 |
| Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists G Chiellini, G Nesi, M Digiacomo, R Malvasi, S Espinoza, M Sabatini, ... Journal of Medicinal Chemistry 58 (12), 5096-5107, 2015 | 54 | 2015 |
| Design and synthesis of H2S-donor hybrids: a new treatment for Alzheimer's disease? S Sestito, L Pruccoli, M Runfola, V Citi, A Martelli, G Saccomanni, ... European Journal of Medicinal Chemistry 184, 111745, 2019 | 52 | 2019 |
| Dual inhibition of PDK1 and Aurora Kinase A: an effective strategy to induce differentiation and apoptosis of human glioblastoma multiforme stem cells S Daniele, S Sestito, D Pietrobono, C Giacomelli, G Chiellini, D Di Maio, ... ACS chemical neuroscience 8 (1), 100-114, 2017 | 51 | 2017 |
| Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on In Vivo Pharmacological Effects and Bioavailability Traits Y Taheri, J Sharifi-Rad, G Antika, YB Yılmaz, TB Tumer, S Abuhamdah, ... Oxidative Medicine and Cellular Longevity 2021, 2021 | 48 | 2021 |
| Design and synthesis of 2-oxindole based multi-targeted inhibitors of PDK1/Akt signaling pathway for the treatment of glioblastoma multiforme S Sestito, G Nesi, S Daniele, A Martelli, M Digiacomo, A Borghini, D Pietra, ... European journal of medicinal chemistry 105, 274-288, 2015 | 46 | 2015 |
| New insights into the potential roles of 3-iodothyronamine (T1AM) and newly developed thyronamine-like TAAR1 agonists in neuroprotection L Bellusci, A Laurino, M Sabatini, S Sestito, P Lenzi, L Raimondi, ... Frontiers in Pharmacology 8, 314283, 2017 | 38 | 2017 |
| New multitarget approaches in the war against glioblastoma: a mini-perspective S Sestito, M Runfola, M Tonelli, G Chiellini, S Rapposelli Frontiers in pharmacology 9, 388950, 2018 | 37 | 2018 |
| Synthesis of novel 3, 5-disubstituted-2-oxindole derivatives as antitumor agents against human nonsmall cell lung cancer G Nesi, S Sestito, V Mey, S Ricciardi, M Falasca, R Danesi, A Lapucci, ... ACS medicinal chemistry letters 4 (12), 1137-1141, 2013 | 29 | 2013 |
| Hydrogen sulfide: a worthwhile tool in the design of new multitarget drugs S Sestito, G Nesi, R Pi, M Macchia, S Rapposelli Frontiers in chemistry 5, 72, 2017 | 26 | 2017 |
Simona RapposelliAssociate professor, Università di PisaVerified email at unipi.it
