Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 220 | 2017 |
Rapid global fitting of large fluorescence lifetime imaging microscopy datasets SC Warren, A Margineanu, D Alibhai, DJ Kelly, C Talbot, Y Alexandrov, ... PloS one 8 (8), e70687, 2013 | 204 | 2013 |
Fluids and their mechanics in tumour transit: shaping metastasis G Follain, D Herrmann, S Harlepp, V Hyenne, N Osmani, SC Warren, ... Nature Reviews Cancer 20 (2), 107-124, 2020 | 199 | 2020 |
Osteoclasts recycle via osteomorphs during RANKL-stimulated bone resorption MM McDonald, WH Khoo, PY Ng, Y Xiao, J Zamerli, P Thatcher, W Kyaw, ... Cell 184 (5), 1330-1347. e13, 2021 | 153 | 2021 |
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019 | 151 | 2019 |
Screening for protein-protein interactions using Förster resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy (FLIM) A Margineanu, JJ Chan, DJ Kelly, SC Warren, D Flatters, S Kumar, ... Scientific reports 6 (1), 1-17, 2016 | 114 | 2016 |
FLIM FRET technology for drug discovery: Automated multiwell‐plate high‐content analysis, multiplexed readouts and application in situ S Kumar, D Alibhai, A Margineanu, R Laine, G Kennedy, J McGinty, ... ChemPhysChem 12 (3), 609-626, 2011 | 89 | 2011 |
A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 80 | 2017 |
Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ... Cell reports 14 (1), 152-167, 2016 | 63 | 2016 |
Multiphoton multispectral fluorescence lifetime tomography for the evaluation of basal cell carcinomas R Patalay, C Talbot, Y Alexandrov, MO Lenz, S Kumar, S Warren, I Munro, ... Public Library of Science 7 (9), e43460, 2012 | 61 | 2012 |
MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ... Science 368 (6495), 1127-1131, 2020 | 58 | 2020 |
Homo-FRET based biosensors and their application to multiplexed imaging of signalling events in live cells SC Warren, A Margineanu, M Katan, C Dunsby, PMW French International journal of molecular sciences 16 (7), 14695-14716, 2015 | 56 | 2015 |
Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer JRW Conway, SC Warren, D Herrmann, KJ Murphy, AS Cazet, C Vennin, ... Cell reports 23 (11), 3312-3326, 2018 | 55 | 2018 |
Automated fluorescence lifetime imaging plate reader and its application to Förster resonant energy transfer readout of Gag protein aggregation D Alibhai, DJ Kelly, S Warren, S Kumar, A Margineau, RA Serwa, ... Journal of biophotonics 6 (5), 398-408, 2013 | 47 | 2013 |
Removing physiological motion from intravital and clinical functional imaging data SC Warren, M Nobis, A Magenau, YH Mohammed, D Herrmann, I Moran, ... Elife 7, e35800, 2018 | 42 | 2018 |
Adaptive multiphoton endomicroscopy through a dynamically deformed multicore optical fiber using proximal detection SC Warren, Y Kim, JM Stone, C Mitchell, JC Knight, MAA Neil, C Paterson, ... Optics express 24 (19), 21474-21484, 2016 | 42 | 2016 |
Application of ultrafast gold luminescence to measuring the instrument response function for multispectral multiphoton fluorescence lifetime imaging CB Talbot, R Patalay, I Munro, S Warren, F Ratto, P Matteini, R Pini, ... Optics Express 19 (15), 13848-13861, 2011 | 39 | 2011 |
Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis M Samuel, P Fonseka, R Sanwlani, L Gangoda, SH Chee, ... Nature Communications 12 (1), 3950, 2021 | 37 | 2021 |
Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors JRW Conway, SC Warren, P Timpson Methods 128, 78-94, 2017 | 36 | 2017 |
Molecular mobility and activity in an intravital imaging setting–implications for cancer progression and targeting M Nobis, SC Warren, MC Lucas, KJ Murphy, D Herrmann, P Timpson Journal of Cell Science 131 (5), jcs206995, 2018 | 33 | 2018 |