FGF23 neutralization improves chronic kidney disease–associated hyperparathyroidism yet increases mortality V Shalhoub, EM Shatzen, SC Ward, J Davis, J Stevens, V Bi, L Renshaw, ... The Journal of clinical investigation 122 (7), 2543-2553, 2012 | 453 | 2012 |
Transcription control by E1A and MAP kinase pathway via Sur2 mediator subunit JL Stevens, GT Cantin, G Wang, A Shevchenko, A Shevchenko, AJ Berk Science 296 (5568), 755-758, 2002 | 305 | 2002 |
Mediator requirement for both recruitment and postrecruitment steps in transcription initiation G Wang, MA Balamotis, JL Stevens, Y Yamaguchi, H Handa, AJ Berk Molecular cell 17 (5), 683-694, 2005 | 237 | 2005 |
A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair M Florio, K Gunasekaran, M Stolina, X Li, L Liu, B Tipton, ... Nature communications 7 (1), 11505, 2016 | 235 | 2016 |
Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex IN Foltz, S Hu, C King, X Wu, C Yang, W Wang, J Weiszmann, J Stevens, ... Science translational medicine 4 (162), 162ra153-162ra153, 2012 | 232 | 2012 |
FGF21 N-and C-termini play different roles in receptor interaction and activation J Yie, R Hecht, J Patel, J Stevens, W Wang, N Hawkins, S Steavenson, ... FEBS letters 583 (1), 19-24, 2009 | 222 | 2009 |
Fibroblast growth factor 23 (FGF23) and alpha-klotho stimulate osteoblastic MC3T3. E1 cell proliferation and inhibit mineralization V Shalhoub, SC Ward, B Sun, J Stevens, L Renshaw, N Hawkins, ... Calcified tissue international 89, 140-150, 2011 | 174 | 2011 |
Co-receptor requirements for fibroblast growth factor-19 signaling X Wu, H Ge, J Gupte, J Weiszmann, G Shimamoto, J Stevens, N Hawkins, ... Journal of Biological Chemistry 282 (40), 29069-29072, 2007 | 169 | 2007 |
Expression of cytochrome P450 genes of the CYP4 family in midgut and fat body of the tobacco hornworm, Manduca sexta MJ Snyder, JL Stevens, JF Andersen, R Feyereisen Archives of biochemistry and biophysics 321 (1), 13-20, 1995 | 156 | 1995 |
Activation domain–mediator interactions promote transcription preinitiation complex assembly on promoter DNA GT Cantin, JL Stevens, AJ Berk Proceedings of the National Academy of Sciences 100 (21), 12003-12008, 2003 | 140 | 2003 |
Inducible P450s of the CYP9 family from larval Manduca sexta midgut JL Stevens, MJ Snyder, JF Koener, R Feyereisen Insect Biochemistry and Molecular Biology 30 (7), 559-568, 2000 | 138 | 2000 |
AMG 757, a half-life extended, DLL3-targeted bispecific T-cell engager, shows high potency and sensitivity in preclinical models of small-cell lung cancer MJ Giffin, K Cooke, EK Lobenhofer, J Estrada, J Zhan, P Deegen, ... Clinical Cancer Research 27 (5), 1526-1537, 2021 | 127 | 2021 |
C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors X Wu, B Lemon, XF Li, J Gupte, J Weiszmann, J Stevens, N Hawkins, ... Journal of biological chemistry 283 (48), 33304-33309, 2008 | 126 | 2008 |
Understanding the Physical Interactions in the FGF21/FGFR/β‐Klotho Complex: Structural Requirements and Implications in FGF21 Signaling J Yie, W Wang, L Deng, LT Tam, J Stevens, MM Chen, Y Li, J Xu, ... Chemical biology & drug design 79 (4), 398-410, 2012 | 114 | 2012 |
Targeting multiple myeloma with AMG 424, a novel anti-CD38/CD3 bispecific T-cell–recruiting antibody optimized for cytotoxicity and cytokine release CL Zuch de Zafra, F Fajardo, W Zhong, MJ Bernett, US Muchhal, ... Clinical Cancer Research 25 (13), 3921-3933, 2019 | 101 | 2019 |
Complexity in transcription control at the activation domain–Mediator interface MA Balamotis, MA Pennella, JL Stevens, B Wasylyk, AS Belmont, AJ Berk Science signaling 2 (69), ra20-ra20, 2009 | 100 | 2009 |
Characterization of mediator complexes from HeLa cell nuclear extract G Wang, GT Cantin, JL Stevens, AJ Berk Molecular and cellular biology 21 (14), 4604-4613, 2001 | 83 | 2001 |
FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein R Smith, A Duguay, A Bakker, P Li, J Weiszmann, MR Thomas, BM Alba, ... PloS one 8 (4), e61432, 2013 | 71 | 2013 |
A novel mammalian cell line development platform utilizing nanofluidics and optoelectro positioning technology K Le, C Tan, S Gupta, T Guhan, H Barkhordarian, J Lull, J Stevens, ... Biotechnology progress 34 (6), 1438-1446, 2018 | 48 | 2018 |
Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line T Tharmalingam, H Barkhordarian, N Tejeda, K Daris, S Yaghmour, ... Biotechnology Progress 34 (3), 613-623, 2018 | 40 | 2018 |