| Cooperative binding of transcription factors orchestrates reprogramming C Chronis, P Fiziev, B Papp, S Butz, G Bonora, S Sabri, J Ernst, K Plath Cell 168 (3), 442-459. e20, 2017 | 493 | 2017 |
| Long-range chromatin contacts in embryonic stem cells reveal a role for pluripotency factors and polycomb proteins in genome organization M Denholtz, G Bonora, C Chronis, E Splinter, W De Laat, J Ernst, ... Cell stem cell 13 (5), 602-616, 2013 | 288 | 2013 |
| Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1γ in reprogramming to pluripotency R Sridharan, M Gonzales-Cope, C Chronis, G Bonora, R McKee, ... Nature cell biology 15 (7), 872-882, 2013 | 257 | 2013 |
| Human naive pluripotent stem cells model X chromosome dampening and X inactivation A Sahakyan, R Kim, C Chronis, S Sabri, G Bonora, TW Theunissen, ... Cell stem cell 20 (1), 87-101, 2017 | 223 | 2017 |
| CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine K Raj, A John, A Ho, C Chronis, S Khan, J Samuel, S Pomplun, ... Leukemia 21 (9), 1937-1944, 2007 | 177 | 2007 |
| A protein assembly mediates Xist localization and gene silencing A Pandya-Jones, Y Markaki, J Serizay, T Chitiashvili, WR Mancia Leon, ... Nature 587 (7832), 145-151, 2020 | 131 | 2020 |
| Human embryonic stem cells do not change their X inactivation status during differentiation S Patel, G Bonora, A Sahakyan, R Kim, C Chronis, J Langerman, ... Cell reports 18 (1), 54-67, 2017 | 111 | 2017 |
| Promoter-enhancer communication occurs primarily within insulated neighborhoods F Sun, C Chronis, M Kronenberg, XF Chen, T Su, FD Lay, K Plath, ... Molecular cell 73 (2), 250-263. e5, 2019 | 86 | 2019 |
| Mechanistic insights into reprogramming to induced pluripotency R Ho, C Chronis, K Plath Journal of cellular physiology 226 (4), 868-878, 2011 | 71 | 2011 |
| Loss of MECP2 leads to activation of P53 and neuronal senescence M Ohashi, E Korsakova, D Allen, P Lee, K Fu, BS Vargas, J Cinkornpumin, ... Stem Cell Reports 10 (5), 1453-1463, 2018 | 59 | 2018 |
| Reducing MCM levels in human primary T cells during the G0→ G1 transition causes genomic instability during the first cell cycle SJ Orr, T Gaymes, D Ladon, C Chronis, B Czepulkowski, R Wang, ... Oncogene 29 (26), 3803-3814, 2010 | 54 | 2010 |
| Mot1, Ino80C, and NC2 function coordinately to regulate pervasive transcription in yeast and mammals Y Xue, SK Pradhan, F Sun, C Chronis, N Tran, T Su, C Van, A Vashisht, ... Molecular cell 67 (4), 594-607. e4, 2017 | 44 | 2017 |
| X chromosome dosage influences DNA methylation dynamics during reprogramming to mouse iPSCs V Pasque, R Karnik, C Chronis, P Petrella, J Langerman, G Bonora, ... Stem cell reports 10 (5), 1537-1550, 2018 | 43 | 2018 |
| A functional assay for microRNA target identification and validation J Gäken, AM Mohamedali, J Jiang, F Malik, D Stangl, AE Smith, C Chronis, ... Nucleic acids research 40 (10), e75-e75, 2012 | 38 | 2012 |
| The BAF and PRC2 complex subunits Dpf2 and Eed antagonistically converge on Tbx3 to control ESC differentiation W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, ... Cell Stem Cell 24 (1), 138-152. e8, 2019 | 34 | 2019 |
| Proteomic and protein interaction network analysis of human T lymphocytes during cell‐cycle entry SJ Orr, DR Boutz, R Wang, C Chronis, NC Lea, T Thayaparan, E Hamilton, ... Molecular systems biology 8 (1), 573, 2012 | 30 | 2012 |
| Epigenetics of human T cells during the G0→ G1 transition AE Smith, C Chronis, M Christodoulakis, SJ Orr, NC Lea, NA Twine, ... Genome research 19 (8), 1325-1337, 2009 | 30 | 2009 |
| DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS) G Bonora, L Rubbi, M Morselli, F Ma, C Chronis, K Plath, M Pellegrini PLoS One 14 (4), e0214368, 2019 | 18 | 2019 |
| Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis H Rho, AR Terry, C Chronis, N Hay Cell metabolism 35 (8), 1406-1423. e8, 2023 | 17 | 2023 |
| Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming K Fu, C Chronis, A Soufi, G Bonora, M Edwards, ST Smale, KS Zaret, ... BMC genomics 19, 1-13, 2018 | 17 | 2018 |
