Diseases associated with leaky hemichannels MA Retamal, EP Reyes, IE García, B Pinto, AD Martínez, C González Frontiers in cellular neuroscience 9, 267, 2015 | 99 | 2015 |
Keratitis-ichthyosis-deafness syndrome-associated Cx26 mutants produce nonfunctional gap junctions but hyperactive hemichannels when co-expressed with wild type Cx43 IE García, J Maripillán, O Jara, R Ceriani, A Palacios-Munoz, ... Journal of Investigative Dermatology 135 (5), 1338-1347, 2015 | 91 | 2015 |
Connexinopathies: a structural and functional glimpse IE García, P Prado, A Pupo, O Jara, D Rojas-Gómez, P Mujica, ... BMC cell biology 17, 71-87, 2016 | 58 | 2016 |
Critical role of the first transmembrane domain of Cx26 in regulating oligomerization and function O Jara, R Acuña, IE García, J Maripillán, V Figueroa, JC Sáez, ... Molecular biology of the cell 23 (17), 3299-3311, 2012 | 53 | 2012 |
From hyperactive connexin26 hemichannels to impairments in epidermal calcium gradient and permeability barrier in the keratitis-ichthyosis-deafness syndrome IE Garcia, F Bosen, P Mujica, A Pupo, C Flores-Munoz, O Jara, ... Journal of Investigative Dermatology 136 (3), 574-583, 2016 | 52 | 2016 |
Characterization of a novel water pocket inside the human Cx26 hemichannel structure R Araya-Secchi, T Perez-Acle, S Kang, T Huynh, A Bernardin, Y Escalona, ... Biophysical journal 107 (3), 599-612, 2014 | 44 | 2014 |
Extracellular cysteine in connexins: role as redox sensors MA Retamal, IE García, BI Pinto, A Pupo, D Báez, J Stehberg, R Del Rio, ... Frontiers in physiology 7, 171782, 2016 | 38 | 2016 |
Abnormal distribution of inositol 1, 4, 5‐trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy‐derived cells C Cárdenas, N Juretić, JA Bevilacqua, IE García, R Figueroa, R Hartley, ... The FASEB Journal 24 (9), 3210-3221, 2010 | 28 | 2010 |
Redox-mediated regulation of connexin proteins; focus on nitric oxide IE Garcia, HA Sánchez, AD Martinez, MA Retamal Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (1), 91-95, 2018 | 25 | 2018 |
Role of connexin channels in the retinal light response of a diurnal rodent A Palacios-Muñoz, MJ Escobar, A Vielma, J Araya, A Astudillo, G Valdivia, ... Frontiers in cellular neuroscience 8, 249, 2014 | 24 | 2014 |
The syndromic deafness mutation G12R impairs fast and slow gating in Cx26 hemichannels IE García, F Villanelo, GF Contreras, A Pupo, BI Pinto, JE Contreras, ... Journal of General Physiology 150 (5), 697-711, 2018 | 19 | 2018 |
The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening JM Valdez Capuccino, P Chatterjee, IE García, WM Botello-Smith, ... Journal of General Physiology 151 (3), 328-341, 2019 | 16 | 2019 |
Restraint of human skin fibroblast motility, migration, and cell surface actin dynamics, by Pannexin 1 and P2X7 receptor signaling C Flores-Muñoz, J Maripillán, J Vásquez-Navarrete, J Novoa-Molina, ... International Journal of Molecular Sciences 22 (3), 1069, 2021 | 15 | 2021 |
Calcium binding and voltage gating in Cx46 hemichannels BI Pinto, A Pupo, IE García, K Mena-Ulecia, AD Martínez, R Latorre, ... Scientific Reports 7 (1), 15851, 2017 | 13 | 2017 |
Charged residues at the first transmembrane region contribute to the voltage dependence of the slow gate of connexins BI Pinto, IE García, A Pupo, MA Retamal, AD Martínez, R Latorre, ... Journal of Biological Chemistry 291 (30), 15740-15752, 2016 | 13 | 2016 |
Mutations in trpγ, the homologue of TRPC6 autism candidate gene, causes autism-like behavioral deficits in Drosophila A Palacios-Muñoz, D de Paula Moreira, V Silva, IE García, F Aboitiz, ... Molecular Psychiatry 27 (8), 3328-3342, 2022 | 8 | 2022 |
Therapeutic perspectives of HIV-associated chemokine receptor (CCR5 and CXCR4) antagonists in carcinomas WA González-Arriagada, IE García, R Martínez-Flores, S Morales-Pison, ... International Journal of Molecular Sciences 24 (1), 478, 2022 | 5 | 2022 |
Expression of KID syndromic mutation Cx26S17F produces hyperactive hemichannels in supporting cells of the organ of Corti AC Abbott, IE García, F Villanelo, C Flores-Muñoz, R Ceriani, J Maripillán, ... Frontiers in Cell and Developmental Biology 10, 1071202, 2023 | 2 | 2023 |
Insights on Gating Functions of Cytosolic Domains of Connexin26 Hemichannels Revealed by a Human Pathogenic Mutation (N14K) JMV Capuccino, P Chatterjee, I Garcia, AL Harris, Y Luo, JE Contreras Biophysical Journal 114 (3), 379a, 2018 | 1 | 2018 |
Is the gain of hemichannel activity a common feature shared by Cx26 syndromic deafness mutants? IE García, MA Retamal, O Jara, C González, AD Martínez Biophysical Journal 104 (2), 492a-493a, 2013 | 1 | 2013 |