Unifying features in protein-folding mechanisms S Gianni, NR Guydosh, F Khan, TD Caldas, U Mayor, GWN White, ... Proceedings of the National Academy of Sciences 100 (23), 13286-13291, 2003 | 299 | 2003 |
PDZ domains: folding and binding P Jemth, S Gianni Biochemistry 46 (30), 8701-8708, 2007 | 197 | 2007 |
Distinguishing induced fit from conformational selection S Gianni, J Dogan, P Jemth Biophysical chemistry 189, 33-39, 2014 | 164 | 2014 |
The binding mechanisms of intrinsically disordered proteins J Dogan, S Gianni, P Jemth Physical Chemistry Chemical Physics 16 (14), 6323-6331, 2014 | 137 | 2014 |
Towards a structural biology of the hydrophobic effect in protein folding C Camilloni, D Bonetti, A Morrone, R Giri, CM Dobson, M Brunori, ... Scientific reports 6 (1), 28285, 2016 | 120 | 2016 |
Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation P Jemth, S Gianni, R Day, B Li, CM Johnson, V Daggett, AR Fersht Proceedings of the National Academy of Sciences 101 (17), 6450-6455, 2004 | 116 | 2004 |
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases G Giardina, R Montioli, S Gianni, B Cellini, A Paiardini, CB Voltattorni, ... Proceedings of the National Academy of sciences 108 (51), 20514-20519, 2011 | 115 | 2011 |
Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering S Gianni, T Walma, A Arcovito, N Calosci, A Bellelli, Å Engström, ... Structure 14 (12), 1801-1809, 2006 | 113 | 2006 |
The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism S Gianni, A Engström, M Larsson, N Calosci, F Malatesta, L Eklund, ... Journal of Biological Chemistry 280 (41), 34805-34812, 2005 | 105 | 2005 |
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system R Giri, A Morrone, A Toto, M Brunori, S Gianni Proceedings of the National Academy of Sciences 110 (37), 14942-14947, 2013 | 104 | 2013 |
The kinetic pathway of folding of barnase F Khan, JI Chuang, S Gianni, AR Fersht Journal of molecular biology 333 (1), 169-186, 2003 | 97 | 2003 |
Identification and characterization of protein folding intermediates S Gianni, Y Ivarsson, P Jemth, M Brunori, C Travaglini-Allocatelli Biophysical chemistry 128 (2-3), 105-113, 2007 | 90 | 2007 |
Molecular recognition by templated folding of an intrinsically disordered protein A Toto, C Camilloni, R Giri, M Brunori, M Vendruscolo, S Gianni Scientific reports 6 (1), 21994, 2016 | 88 | 2016 |
Coupled binding and folding of intrinsically disordered proteins: what can we learn from kinetics? S Gianni, J Dogan, P Jemth Current opinion in structural biology 36, 18-24, 2016 | 84 | 2016 |
Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate C Savino, LC Montemiglio, G Sciara, AE Miele, SG Kendrew, P Jemth, ... Journal of Biological Chemistry 284 (42), 29170-29179, 2009 | 77 | 2009 |
A PDZ domain recapitulates a unifying mechanism for protein folding S Gianni, CD Geierhaas, N Calosci, P Jemth, GW Vuister, ... Proceedings of the National Academy of Sciences 104 (1), 128-133, 2007 | 76 | 2007 |
A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein S Gianni, A Morrone, R Giri, M Brunori Biochemical and biophysical research communications 428 (2), 205-209, 2012 | 75 | 2012 |
An Obligatory Intermediate in the Folding Pathway of Cytochromec552 from Hydrogenobacterthermophilus C Travaglini-Allocatelli, S Gianni, VK Dubey, A Borgia, A Di Matteo, ... Journal of Biological Chemistry 280 (27), 25729-25734, 2005 | 75 | 2005 |
Ligand binding by PDZ domains CN Chi, A Bach, K Strømgaard, S Gianni, P Jemth Biofactors 38 (5), 338-348, 2012 | 73 | 2012 |
Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding GWN White, S Gianni, JG Grossmann, P Jemth, AR Fersht, V Daggett Journal of molecular biology 350 (4), 757-775, 2005 | 71 | 2005 |