Stefano Gianni
Stefano Gianni
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Cited by
Cited by
Unifying features in protein-folding mechanisms
S Gianni, NR Guydosh, F Khan, TD Caldas, U Mayor, GWN White, ...
Proceedings of the National Academy of Sciences 100 (23), 13286-13291, 2003
PDZ domains: folding and binding
P Jemth, S Gianni
Biochemistry 46 (30), 8701-8708, 2007
Distinguishing induced fit from conformational selection
S Gianni, J Dogan, P Jemth
Biophysical chemistry 189, 33-39, 2014
The binding mechanisms of intrinsically disordered proteins
J Dogan, S Gianni, P Jemth
Physical Chemistry Chemical Physics 16 (14), 6323-6331, 2014
Towards a structural biology of the hydrophobic effect in protein folding
C Camilloni, D Bonetti, A Morrone, R Giri, CM Dobson, M Brunori, ...
Scientific reports 6 (1), 28285, 2016
Demonstration of a low-energy on-pathway intermediate in a fast-folding protein by kinetics, protein engineering, and simulation
P Jemth, S Gianni, R Day, B Li, CM Johnson, V Daggett, AR Fersht
Proceedings of the National Academy of Sciences 101 (17), 6450-6455, 2004
Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases
G Giardina, R Montioli, S Gianni, B Cellini, A Paiardini, CB Voltattorni, ...
Proceedings of the National Academy of sciences 108 (51), 20514-20519, 2011
Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering
S Gianni, T Walma, A Arcovito, N Calosci, A Bellelli, Å Engström, ...
Structure 14 (12), 1801-1809, 2006
The kinetics of PDZ domain-ligand interactions and implications for the binding mechanism
S Gianni, A Engström, M Larsson, N Calosci, F Malatesta, L Eklund, ...
Journal of Biological Chemistry 280 (41), 34805-34812, 2005
Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system
R Giri, A Morrone, A Toto, M Brunori, S Gianni
Proceedings of the National Academy of Sciences 110 (37), 14942-14947, 2013
The kinetic pathway of folding of barnase
F Khan, JI Chuang, S Gianni, AR Fersht
Journal of molecular biology 333 (1), 169-186, 2003
Identification and characterization of protein folding intermediates
S Gianni, Y Ivarsson, P Jemth, M Brunori, C Travaglini-Allocatelli
Biophysical chemistry 128 (2-3), 105-113, 2007
Molecular recognition by templated folding of an intrinsically disordered protein
A Toto, C Camilloni, R Giri, M Brunori, M Vendruscolo, S Gianni
Scientific reports 6 (1), 21994, 2016
Coupled binding and folding of intrinsically disordered proteins: what can we learn from kinetics?
S Gianni, J Dogan, P Jemth
Current opinion in structural biology 36, 18-24, 2016
Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate
C Savino, LC Montemiglio, G Sciara, AE Miele, SG Kendrew, P Jemth, ...
Journal of Biological Chemistry 284 (42), 29170-29179, 2009
A PDZ domain recapitulates a unifying mechanism for protein folding
S Gianni, CD Geierhaas, N Calosci, P Jemth, GW Vuister, ...
Proceedings of the National Academy of Sciences 104 (1), 128-133, 2007
A folding-after-binding mechanism describes the recognition between the transactivation domain of c-Myb and the KIX domain of the CREB-binding protein
S Gianni, A Morrone, R Giri, M Brunori
Biochemical and biophysical research communications 428 (2), 205-209, 2012
An Obligatory Intermediate in the Folding Pathway of Cytochromec552 from Hydrogenobacterthermophilus
C Travaglini-Allocatelli, S Gianni, VK Dubey, A Borgia, A Di Matteo, ...
Journal of Biological Chemistry 280 (27), 25729-25734, 2005
Ligand binding by PDZ domains
CN Chi, A Bach, K Strømgaard, S Gianni, P Jemth
Biofactors 38 (5), 338-348, 2012
Simulation and experiment conspire to reveal cryptic intermediates and a slide from the nucleation-condensation to framework mechanism of folding
GWN White, S Gianni, JG Grossmann, P Jemth, AR Fersht, V Daggett
Journal of molecular biology 350 (4), 757-775, 2005
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