| Chimeric antigen receptor T cells for sustained remissions in leukemia SL Maude, N Frey, PA Shaw, R Aplenc, DM Barrett, NJ Bunin, A Chew, ... New England Journal of Medicine 371 (16), 1507-1517, 2014 | 5010 | 2014 |
| Chimeric antigen receptor–modified T cells in chronic lymphoid leukemia DL Porter, BL Levine, M Kalos, A Bagg, CH June N engl j Med 365, 725-733, 2011 | 4043 | 2011 |
| Chimeric antigen receptor–modified T cells for acute lymphoid leukemia SA Grupp, M Kalos, D Barrett, R Aplenc, DL Porter, SR Rheingold, ... New England Journal of Medicine 368 (16), 1509-1518, 2013 | 3663 | 2013 |
| Tisagenlecleucel in children and young adults with B-cell lymphoblastic leukemia SL Maude, TW Laetsch, J Buechner, S Rives, M Boyer, H Bittencourt, ... New England Journal of Medicine 378 (5), 439-448, 2018 | 3609 | 2018 |
| T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia M Kalos, BL Levine, DL Porter, S Katz, SA Grupp, A Bagg, CH June Science translational medicine 3 (95), 95ra73-95ra73, 2011 | 2883 | 2011 |
| Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia DL Porter, WT Hwang, NV Frey, SF Lacey, PA Shaw, AW Loren, A Bagg, ... Science translational medicine 7 (303), 303ra139-303ra139, 2015 | 1584 | 2015 |
| Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV P Tebas, D Stein, WW Tang, I Frank, SQ Wang, G Lee, SK Spratt, ... New England Journal of Medicine 370 (10), 901-910, 2014 | 1570 | 2014 |
| Chimeric antigen receptor T cells in refractory B-cell lymphomas SJ Schuster, J Svoboda, EA Chong, SD Nasta, AR Mato, Ö Anak, ... New England Journal of Medicine 377 (26), 2545-2554, 2017 | 1412 | 2017 |
| A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ... Science translational medicine 9 (399), eaaa0984, 2017 | 1193 | 2017 |
| Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics CG Brunstein, JS Miller, Q Cao, DH McKenna, KL Hippen, J Curtsinger, ... Blood, The Journal of the American Society of Hematology 117 (3), 1061-1070, 2011 | 1131 | 2011 |
| Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma GP Linette, EA Stadtmauer, MV Maus, AP Rapoport, BL Levine, L Emery, ... Blood, The Journal of the American Society of Hematology 122 (6), 863-871, 2013 | 1080 | 2013 |
| Engineered T cells: the promise and challenges of cancer immunotherapy AD Fesnak, CH June, BL Levine Nature reviews cancer 16 (9), 566-581, 2016 | 1018 | 2016 |
| Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia JA Fraietta, SF Lacey, EJ Orlando, I Pruteanu-Malinici, M Gohil, S Lundh, ... Nature medicine 24 (5), 563-571, 2018 | 1011 | 2018 |
| NY-ESO-1–specific TCR–engineered T cells mediate sustained antigen-specific antitumor effects in myeloma AP Rapoport, EA Stadtmauer, GK Binder-Scholl, O Goloubeva, DT Vogl, ... Nature medicine 21 (8), 914-921, 2015 | 852 | 2015 |
| CRISPR-engineered T cells in patients with refractory cancer EA Stadtmauer, JA Fraietta, MM Davis, AD Cohen, KL Weber, E Lancaster, ... Science 367 (6481), eaba7365, 2020 | 827 | 2020 |
| Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia DT Teachey, SF Lacey, PA Shaw, JJ Melenhorst, SL Maude, N Frey, ... Cancer discovery 6 (6), 664-679, 2016 | 820 | 2016 |
| Mesothelin-Specific Chimeric Antigen Receptor mRNA-Engineered T Cells Induce Antitumor Activity in Solid MalignanciesCase Report: RNA CAR T Cells GL Beatty, AR Haas, MV Maus, DA Torigian, MC Soulen, G Plesa, ... Cancer immunology research 2 (2), 112-120, 2014 | 813 | 2014 |
| Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells J Scholler, TL Brady, G Binder-Scholl, WT Hwang, G Plesa, KM Hege, ... Science translational medicine 4 (132), 132ra53-132ra53, 2012 | 690 | 2012 |
| Identification of a Titin-derived HLA-A1–presented peptide as a cross-reactive target for engineered MAGE A3–directed T cells BJ Cameron, AB Gerry, J Dukes, JV Harper, V Kannan, FC Bianchi, ... Science translational medicine 5 (197), 197ra103-197ra103, 2013 | 626 | 2013 |
| Gene transfer in humans using a conditionally replicating lentiviral vector BL Levine, LM Humeau, J Boyer, RR MacGregor, T Rebello, X Lu, ... Proceedings of the National Academy of Sciences 103 (46), 17372-17377, 2006 | 609 | 2006 |
Carl JuneUniversity of PennsylvaniaVerified email at upenn.edu
