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J David Becherer
J David Becherer
VP R & D
Verified email at immventionthera.com
Title
Cited by
Cited by
Year
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
ML Moss, SLC Jin, ME Milla, W Burkhart, HL Carter, WJ Chen, WC Clay, ...
Nature 385 (6618), 733-736, 1997
21091997
Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor
GM McGeehan, JD Becherer, RC Bast Jr, CM Boyer, B Champion, ...
Nature 370 (6490), 558-561, 1994
7241994
Evidence for a role of a tumor necrosis factor-α (TNF-α)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic …
L Lum, BR Wong, R Josien, JD Becherer, H Erdjument-Bromage, ...
Journal of Biological Chemistry 274 (19), 13613-13618, 1999
5901999
Intracellular maturation and localization of the tumour necrosis factor α convertase (TACE)
J Schlöndorff, JD Becherer, CP Blobel
Biochemical Journal 347 (1), 131-138, 2000
4892000
Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity
M Roghani, JD Becherer, ML Moss, RE Atherton, H Erdjument-Bromage, ...
Journal of Biological Chemistry 274 (6), 3531-3540, 1999
4151999
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell …
A Ludwig, C Hundhausen, MH Lambert, N Broadway, RC Andrews, ...
Combinatorial chemistry & high throughput screening 8 (2), 161-171, 2005
4142005
Involvement of the proteasome in the programmed cell death of NGF‐deprived sympathetic neurons.
R Sadoul, PA Fernandez, AL Quiquerez, I Martinou, M Maki, M Schröter, ...
The EMBO journal 15 (15), 3845-3852, 1996
3311996
The Τumor Necrosis Factor-α Converting Enzyme (TACE): A Unique Metalloproteinase with Highly Defined Substrate Selectivity
MJ Mohan, T Seaton, J Mitchell, A Howe, K Blackburn, W Burkhart, ...
Biochemistry 41 (30), 9462-9469, 2002
3012002
Granzyme A is an interleukin 1 beta-converting enzyme.
M Irmler, S Hertig, HR MacDonald, R Sadoul, JD Becherer, A Proudfoot, ...
The Journal of experimental medicine 181 (5), 1917-1922, 1995
2861995
A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ decline
MG Tarragó, CCS Chini, KS Kanamori, GM Warner, A Caride, ...
Cell metabolism 27 (5), 1081-1095. e10, 2018
2742018
ADAM10 is a principal'sheddase'of the low-affinity immunoglobulin E receptor CD23
G Weskamp, JW Ford, J Sturgill, S Martin, AJP Docherty, S Swendeman, ...
Nature immunology 7 (12), 1293-1298, 2006
2722006
Altered tumor necrosis factor-α (TNF-α) processing in adipocytes and increased expression of transmembrane TNF-α in obesity
H Xu, KT Uysal, JD Becherer, P Arner, GS Hotamisligil
Diabetes 51 (6), 1876-1883, 2002
2702002
Specific sequence elements are required for the expression of functional tumor necrosis factor-α-converting enzyme (TACE)
ME Milla, MA Leesnitzer, ML Moss, WC Clay, HL Carter, AB Miller, JL Su, ...
Journal of Biological Chemistry 274 (43), 30563-30570, 1999
2271999
Evidence for a critical role of the tumor necrosis factor α convertase (TACE) in ectodomain shedding of the p75 neurotrophin receptor (p75NTR)
G Weskamp, J Schlöndorff, L Lum, JD Becherer, TW Kim, P Saftig, ...
Journal of Biological Chemistry 279 (6), 4241-4249, 2004
2022004
The enzymatic activity of ADAM8 and ADAM9 is not regulated by TIMPs
A Amour, CG Knight, WR English, A Webster, PM Slocombe, V Knäuper, ...
FEBS letters 524 (1-3), 154-158, 2002
1852002
Structural features and biochemical properties of TNF-α converting enzyme (TACE)
ML Moss, SLC Jin, JD Becherer, DM Bickett, W Burkhart, WJ Chen, ...
Journal of neuroimmunology 72 (2), 127-129, 1997
1721997
Catalytic properties of ADAM19
V Chesneau, JD Becherer, Y Zheng, H Erdjument-Bromage, P Tempst, ...
Journal of Biological Chemistry 278 (25), 22331-22340, 2003
1562003
Biochemical properties and functions of membrane-anchored metalloprotease-disintegrin proteins (ADAMs)
JD Becherer, CP Blobel
Academic Press 54, 101-123, 2003
1312003
Dissection of CR1, factor H, membrane cofactor protein, and factor B binding and functional sites in the third complement component.
JD Lambris, Z Lao, TJ Oglesby, JP Atkinson, CE Hack, JD Becherer
Journal of immunology (Baltimore, Md.: 1950) 156 (12), 4821-4832, 1996
1261996
Discovery, synthesis, and biological evaluation of thiazoloquin (az) olin (on) es as potent CD38 inhibitors
CD Haffner, JD Becherer, EE Boros, R Cadilla, T Carpenter, D Cowan, ...
Journal of medicinal chemistry 58 (8), 3548-3571, 2015
1212015
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