Celecoxib analogs bearing benzofuran moiety as cyclooxygenase-2 inhibitors: design, synthesis and evaluation as potential anti-inflammatory agents GS Hassan, SM Abou-Seri, G Kamel, MM Ali European journal of medicinal chemistry 76, 482-493, 2014 | 161 | 2014 |
Synthesis and biological evaluation of novel coumarin–pyrazoline hybrids endowed with phenylsulfonyl moiety as antitumor agents KM Amin, AAM Eissa, SM Abou-Seri, FM Awadallah, GS Hassan European journal of medicinal chemistry 60, 187-198, 2013 | 152 | 2013 |
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents AH Abadi, SM Abou-Seri, DE Abdel-Rahman, C Klein, O Lozach, L Meijer European journal of medicinal chemistry 41 (3), 296-305, 2006 | 149 | 2006 |
1-Piperazinylphthalazines as potential VEGFR-2 inhibitors and anticancer agents: synthesis and in vitro biological evaluation SM Abou-Seri, WM Eldehna, MM Ali, DAA El Ella European journal of medicinal chemistry 107, 165-179, 2016 | 133 | 2016 |
Isatin-pyrazole benzenesulfonamide hybrids potently inhibit tumor-associated carbonic anhydrase isoforms IX and XII HS Ibrahim, SM Abou-Seri, M Tanc, MM Elaasser, HA Abdel-Aziz, ... European journal of medicinal chemistry 103, 583-593, 2015 | 123 | 2015 |
Synthesis and antitumor activity of pyrido [2, 3-d] pyrimidine and pyrido [2, 3-d][1, 2, 4] triazolo [4, 3-a] pyrimidine derivatives that induce apoptosis through G1 cell-cycle … M Fares, SM Abou-Seri, HA Abdel-Aziz, SES Abbas, MM Youssef, ... European journal of medicinal chemistry 83, 155-166, 2014 | 116 | 2014 |
Synthesis and in vitro cytotoxic activity of novel pyrazolo [3, 4-d] pyrimidines and related pyrazole hydrazones toward breast adenocarcinoma MCF-7 cell line GS Hassan, HH Kadry, SM Abou-Seri, MM Ali, AEED Mahmoud Bioorganic & medicinal chemistry 19 (22), 6808-6817, 2011 | 106 | 2011 |
Design, synthesis and vasorelaxant evaluation of novel coumarin–pyrimidine hybrids KM Amin, FM Awadalla, AAM Eissa, SM Abou-Seri, GS Hassan Bioorganic & medicinal chemistry 19 (20), 6087-6097, 2011 | 101 | 2011 |
Synthesis and biological evaluation of novel 2, 4′-bis substituted diphenylamines as anticancer agents and potential epidermal growth factor receptor tyrosine kinase inhibitors SM Abou-Seri European journal of medicinal chemistry 45 (9), 4113-4121, 2010 | 95 | 2010 |
Novel indole-thiazolidinone conjugates: Design, synthesis and whole-cell phenotypic evaluation as a novel class of antimicrobial agents MF Abo-Ashour, WM Eldehna, RF George, MM Abdel-Aziz, MM Elaasser, ... European journal of medicinal chemistry 160, 49-60, 2018 | 94 | 2018 |
Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1 … WM Eldehna, SM Abou-Seri, AM El Kerdawy, RR Ayyad, AM Hamdy, ... European Journal of Medicinal Chemistry 113, 50-62, 2016 | 89 | 2016 |
Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII WM Eldehna, M Fares, M Ceruso, HA Ghabbour, SM Abou-Seri, ... European Journal of Medicinal Chemistry 110, 259-266, 2016 | 85 | 2016 |
3-Hydrazinoisatin-based benzenesulfonamides as novel carbonic anhydrase inhibitors endowed with anticancer activity: Synthesis, in vitro biological evaluation and in silico … MF Abo-Ashour, WM Eldehna, A Nocentini, A Bonardi, S Bua, HS Ibrahim, ... European Journal of Medicinal Chemistry 184, 111768, 2019 | 80 | 2019 |
Design, synthesis and anticancer activity of new monastrol analogues bearing 1, 3, 4-oxadiazole moiety FAF Ragab, SM Abou-Seri, SA Abdel-Aziz, AM Alfayomy, M Aboelmagd European journal of medicinal chemistry 138, 140-151, 2017 | 78 | 2017 |
Synthesis and anticancer activity of some 8-substituted-7-methoxy-2H-chromen-2-one derivatives toward hepatocellular carcinoma HepG2 cells KM Amin, SM Abou-Seri, FM Awadallah, AAM Eissa, GS Hassan, ... European journal of medicinal chemistry 90, 221-231, 2015 | 71 | 2015 |
Bis-isatin hydrazones with novel linkers: Synthesis and biological evaluation as cytotoxic agents HS Ibrahim, SM Abou-seri, NSM Ismail, MM Elaasser, MH Aly, ... European journal of medicinal chemistry 108, 415-422, 2016 | 70 | 2016 |
Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking WM Eldehna, M Fares, HS Ibrahim, MH Aly, S Zada, MM Ali, ... European journal of medicinal chemistry 100, 89-97, 2015 | 63 | 2015 |
Design, Synthesis and In Vitro Antiproliferative Activity of Novel Isatin‐Quinazoline Hybrids M Fares, WM Eldehna, SM Abou‐Seri, HA Abdel‐Aziz, MH Aly, MF Tolba Archiv der Pharmazie 348 (2), 144-154, 2015 | 59 | 2015 |
Novel synthesized SLC-0111 thiazole and thiadiazole analogues: Determination of their carbonic anhydrase inhibitory activity and molecular modeling studies MF Abo-Ashour, WM Eldehna, A Nocentini, HS Ibrahim, S Bua, ... Bioorganic chemistry 87, 794-802, 2019 | 58 | 2019 |
Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation MA Said, WM Eldehna, A Nocentini, SH Fahim, A Bonardi, AA Elgazar, ... European Journal of Medicinal Chemistry 189, 112019, 2020 | 57 | 2020 |