| Evaluation of off-target and on-target scoring algorithms and integration into the guide RNA selection tool CRISPOR M Haeussler, K Schönig, H Eckert, A Eschstruth, J Mianné, JB Renaud, ... Genome biology 17, 1-12, 2016 | 1594 | 2016 |
| Prevalence of sexual dimorphism in mammalian phenotypic traits NA Karp, J Mason, AL Beaudet, Y Benjamini, L Bower, RE Braun, ... Nature communications 8 (1), 15475, 2017 | 235 | 2017 |
| Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis P Fratta, P Sivakumar, J Humphrey, K Lo, T Ricketts, H Oliveira, ... The EMBO journal 37 (11), e98684, 2018 | 152 | 2018 |
| Correction of the auditory phenotype in C57BL/6N mice via CRISPR/Cas9-mediated homology directed repair J Mianné, L Chessum, S Kumar, C Aguilar, G Codner, M Hutchison, ... Genome medicine 8, 1-12, 2016 | 127 | 2016 |
| Analysing the outcome of CRISPR-aided genome editing in embryos: Screening, genotyping and quality control J Mianné, GF Codner, A Caulder, R Fell, M Hutchison, R King, ME Stewart, ... Methods 121, 68-76, 2017 | 89 | 2017 |
| Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants GF Codner, J Mianné, A Caulder, J Loeffler, R Fell, R King, AJ Allan, ... BMC biology 16, 1-16, 2018 | 82 | 2018 |
| Recurrent genetic abnormalities in human pluripotent stem cells: definition and routine detection in culture supernatant by targeted droplet digital PCR S Assou, N Girault, M Plinet, J Bouckenheimer, C Sansac, M Combe, ... Stem Cell Reports 14 (1), 1-8, 2020 | 67 | 2020 |
| Aneuploidy screening of embryonic stem cell clones by metaphase karyotyping and droplet digital polymerase chain reaction GF Codner, L Lindner, A Caulder, M Wattenhofer-Donzé, A Radage, ... BMC Cell Biology 17, 1-13, 2016 | 28 | 2016 |
| Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo S Laber, S Forcisi, L Bentley, J Petzold, F Moritz, KS Smirnov, L Al Sadat, ... Science advances 7 (30), eabg0108, 2021 | 25 | 2021 |
| Induced pluripotent stem cells for primary ciliary dyskinesia modeling and personalized medicine J Mianné, E Ahmed, C Bourguignon, M Fieldes, I Vachier, A Bourdin, ... American journal of respiratory cell and molecular biology 59 (6), 672-683, 2018 | 25 | 2018 |
| CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles J Mianné, A Nasri, CN Van, C Bourguignon, M Fieldès, E Ahmed, ... BMC biology 20, 1-15, 2022 | 17 | 2022 |
| Pipeline for the generation and characterization of transgenic human pluripotent stem cells using the CRISPR/Cas9 technology J Mianné, C Bourguignon, C Nguyen Van, M Fieldès, A Nasri, S Assou, ... Cells 9 (5), 1312, 2020 | 11 | 2020 |
| Generation of the induced pluripotent stem cell line UHOMi001-A from a patient with mutations in CCDC40 gene causing Primary Ciliary Dyskinesia (PCD) E Ahmed, C Sansac, M Fieldes, A Bergougnoux, C Bourguignon, ... Stem cell research 33, 15-19, 2018 | 10 | 2018 |
| A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits K Cleverley, WC Lee, P Mumford, T Collins, M Rickman, TJ Cunningham, ... Mammalian Genome 32, 94-103, 2021 | 9 | 2021 |
| Differentiation of Human Induced Pluripotent Stem Cells from Patients with Severe COPD into Functional Airway Epithelium E Ahmed, M Fieldes, C Bourguignon, J Mianné, A Petit, M Jory, ... Cells 11 (15), 2422, 2022 | 8 | 2022 |
| Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight C Livermore, N Warr, N Chalon, P Siggers, J Mianné, G Codner, L Teboul, ... Scientific Reports 9 (1), 17195, 2019 | 8 | 2019 |
| Application of long-read sequencing for robust identification of correct alleles in genome edited animals CV McCabe, GF Codner, AJ Allan, A Caulder, S Christou, J Loeffler, ... bioRxiv, 838193, 2019 | 8 | 2019 |
| Targeted mutations in the mouse via embryonic stem cells M Gertsenstein, J Mianné, L Teboul, LMJ Nutter Transgenic Mouse: Methods and Protocols, 59-82, 2020 | 6 | 2020 |
| Generation of four severe early-onset chronic obstructive pulmonary disease (COPD) patient-derived induced pluripotent stem cell lines from peripheral blood mononuclear cells E Ahmed, M Fieldes, J Mianné, C Bourguignon, A Nasri, I Vachier, ... Stem Cell Research 56, 102550, 2021 | 3 | 2021 |
| Generation of the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor M Fieldes, E Ahmed, C Bourguignon, J Mianné, M Martin, C Arnould, ... Stem Cell Research 49, 102037, 2020 | 3 | 2020 |
Lydia TeboulMary Lyon Centre - MRC HarwellVerified email at har.mrc.ac.uk
