| Integrative model of the response of yeast to osmotic shock E Klipp, B Nordlander, R Krüger, P Gennemark, S Hohmann Nature biotechnology 23 (8), 975-982, 2005 | 534 | 2005 |
| Models from experiments: combinatorial drug perturbations of cancer cells S Nelander, W Wang, B Nilsson, QB She, C Pratilas, N Rosen, ... Molecular systems biology 4 (1), 216, 2008 | 211 | 2008 |
| Network modeling of the transcriptional effects of copy number aberrations in glioblastoma R Jörnsten, T Abenius, T Kling, L Schmidt, E Johansson, TEM Nordling, ... Molecular systems biology 7 (1), 486, 2011 | 109 | 2011 |
| Structural and functional characterization of a specific antidote for ticagrelor A Buchanan, P Newton, S Pehrsson, T Inghardt, T Antonsson, ... Blood, The Journal of the American Society of Hematology 125 (22), 3484-3490, 2015 | 97 | 2015 |
| An oral antisense oligonucleotide for PCSK9 inhibition P Gennemark, K Walter, N Clemmensen, D Rekić, CAM Nilsson, ... Science Translational Medicine 13 (593), eabe9117, 2021 | 88 | 2021 |
| Efficient algorithms for ordinary differential equation model identification of biological systems P Gennemark, D Wedelin IET Systems Biology 1 (2), 120-129, 2007 | 68 | 2007 |
| Unlock the thermogenic potential of adipose tissue: pharmacological modulation and implications for treatment of diabetes and obesity XR Peng, P Gennemark, G O’Mahony, S Bartesaghi Frontiers in endocrinology 6, 174, 2015 | 66 | 2015 |
| Benchmarks for identification of ordinary differential equations from time series data P Gennemark, D Wedelin Bioinformatics 25 (6), 780-786, 2009 | 64 | 2009 |
| PPARγ and PPARα synergize to induce robust browning of white fat in vivo T Kroon, M Harms, S Maurer, L Bonnet, I Alexandersson, A Lindblom, ... Molecular metabolism 36, 100964, 2020 | 59 | 2020 |
| Discovery of (3-(4-(2-oxa-6-azaspiro [3.3] heptan-6-ylmethyl) phenoxy) azetidin-1-yl)(5-(4-methoxyphenyl)-1, 3, 4-oxadiazol-2-yl) methanone (AZD1979), a melanin concentrating … A Johansson, C Lofberg, M Antonsson, S von Unge, MA Hayes, R Judkins, ... Journal of Medicinal Chemistry 59 (6), 2497-2511, 2016 | 55 | 2016 |
| A simple mathematical model of adaptation to high osmolarity in yeast P Gennemark, B Nordlander, S Hohmann, D Wedelin In silico biology 6 (3), 193-214, 2006 | 54 | 2006 |
| Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin S Pehrsson, KJ Johansson, A Janefeldt, AS Sandinge, S Maqbool, ... Journal of Thrombosis and Haemostasis 15 (6), 1213-1222, 2017 | 28 | 2017 |
| Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates L Weidolf, A Björkbom, A Dahlen, M Elebring, P Gennemark, M Hölttä, ... Drug discovery today 26 (10), 2244-2258, 2021 | 23 | 2021 |
| A modeling approach for compounds affecting body composition P Gennemark, R Jansson-Löfmark, G Hyberg, M Wigstrand, D Kakol-Palm, ... Journal of pharmacokinetics and pharmacodynamics 40, 651-667, 2013 | 21 | 2013 |
| Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes E Nyman, YJW Rozendaal, G Helmlinger, B Hamrén, MC Kjellsson, ... Interface focus 6 (2), 20150075, 2016 | 20 | 2016 |
| Formal representation of the high osmolarity glycerol pathway in yeast C Kühn, KVS Prasad, E Klipp, P Gennemark Genome Informatics 2009: Genome Informatics Series Vol. 22, 69-83, 2010 | 18 | 2010 |
| Effects of a novel potent melanin‐concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs K Ploj, L Benthem, D Kakol‐Palm, P Gennemark, L Andersson, M Bjursell, ... British Journal of Pharmacology 173 (18), 2739-2751, 2016 | 17 | 2016 |
| Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes E Nyman, S Bartesaghi, R Melin Rydfalk, S Eng, C Pollard, P Gennemark, ... NPJ systems biology and applications 3 (1), 29, 2017 | 16 | 2017 |
| Hybrid modelling for stroke care: Review and suggestions of new approaches for risk assessment and simulation of scenarios T Herrgårdh, VI Madai, JD Kelleher, R Magnusson, M Gustafsson, ... NeuroImage: Clinical 31, 102694, 2021 | 15 | 2021 |
| Quantifying and communicating uncertainty in preclinical human dose‐prediction M Sundqvist, A Lundahl, MB Någård, U Bredberg, P Gennemark CPT: pharmacometrics & systems pharmacology 4 (4), 243-254, 2015 | 15 | 2015 |
