| CRISPR-mediated TCR replacement generates superior anticancer transgenic T cells M Legut, G Dolton, AA Mian, OG Ottmann, AK Sewell Blood, The Journal of the American Society of Hematology 131 (3), 311-322, 2018 | 216 | 2018 |
| PF-114, a potent and selective inhibitor of native and mutated BCR/ABL is active against Philadelphia chromosome-positive (Ph+) leukemias harboring the T315I mutation AA Mian, A Rafiei, I Haberbosch, A Zeifman, I Titov, V Stroylov, ... Leukemia 29 (5), 1104-1114, 2015 | 64 | 2015 |
| Targeting of the N‐terminal coiled coil oligomerization interface by a helix‐2 peptide inhibits unmutated and imatinib‐resistant BCR/ABL T Beissert, A Hundertmark, V Kaburova, L Travaglini, AA Mian, C Nervi, ... International journal of cancer 122 (12), 2744-2752, 2008 | 58 | 2008 |
| The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of … AA Mian, M Schüll, Z Zhao, C Oancea, A Hundertmark, T Beissert, ... Leukemia 23 (9), 1614-1621, 2009 | 52 | 2009 |
| Oligomerization inhibition, combined with allosteric inhibition, abrogates the transformation potential of T315I-positive BCR/ABL AA Mian, C Oancea, Z Zhao, OG Ottmann, M Ruthardt Leukemia 23 (12), 2242-2247, 2009 | 38 | 2009 |
| Linkage Group-Chromosome Correlation in a Mosquito: Inversions in Culex tritaeniorhynchus RH BAKER, RK SAKAI, A MIAN Journal of heredity 62 (1), 31-36, 1971 | 32 | 1971 |
| Linkage group-chromosome correlation in a mosquito. Translocations in Culex tritaeniorhynchus. RK Sakai, RH Baker, A Mian | 31 | 1971 |
| Overcoming Bcr-Abl T315I mutation by combination of GNF-2 and ATP competitors in an Abl-independent mechanism M Khateb, N Ruimi, H Khamisie, Y Najajreh, A Mian, A Metodieva, ... BMC cancer 12, 1-10, 2012 | 28 | 2012 |
| Allosteric inhibition enhances the efficacy of ABL kinase inhibitors to target unmutated BCR-ABL and BCR-ABL-T315I AA Mian, A Metodieva, S Badura, M Khateb, N Ruimi, Y Najajreh, ... BMC cancer 12, 1-8, 2012 | 28 | 2012 |
| Linkage group-chromosome correlation in Culex tritaeniorhynchus RH Baker, RK Sakai, A Mian Science 171 (3971), 585-587, 1971 | 22 | 1971 |
| The functional interplay between the t (9; 22)-associated fusion proteins BCR/ABL and ABL/BCR in Philadelphia chromosome-positive acute lymphatic leukemia A Rafiei, AA Mian, C Doering, A Metodieva, C Oancea, FB Thalheimer, ... PLoS genetics 11 (4), e1005144, 2015 | 20 | 2015 |
| STAT activation status differentiates leukemogenic from non-leukemogenic stem cells in AML and is suppressed by arsenic in t (6; 9)-positive AML C Oancea, B Rüster, B Brill, J Roos, M Heinssmann, G Bug, AA Mian, ... Genes & cancer 5 (11-12), 378, 2014 | 19 | 2014 |
| Seroprevalence of cytomegalovirus, herpes simplex virus and rubella virus among pregnant women in KPK province of Pakistan S Ali, FA Khan, AA Mian, MS Afzal The Journal of Infection in Developing Countries 8 (03), 389-390, 2014 | 14 | 2014 |
| p185BCR/ABL has a lower sensitivity than p210BCR/ABL to the allosteric inhibitor GNF-2 in Philadelphia chromosome-positive acute lymphatic leukemia AA Mian, A Metodieva, Y Najajreh, OG Ottmann, J Mahajna, M Ruthardt haematologica 97 (2), 251, 2012 | 14 | 2012 |
| The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis AA Mian, I Baumann, M Liebermann, F Grebien, G Superti-Furga, ... Leukemia 33 (9), 2319-2323, 2019 | 13 | 2019 |
| Crizotinib acts as ABL1 inhibitor combining ATP-binding with allosteric inhibition and is active against native BCR-ABL1 and its resistance and compound mutants BCR-ABL1T315I … AA Mian, I Haberbosch, H Khamaisie, A Agbarya, L Pietsch, E Eshel, ... Annals of hematology 100 (8), 2023-2029, 2021 | 10 | 2021 |
| STERILITY ENHANCEMENT IN THE MOSQUITO, CULEX TRITAENIORHYNCHUS RK Sakai, RH Baker, A Mian, S Said Canadian journal of Genetics and Cytology 14 (2), 215-220, 1972 | 8 | 1972 |
| BCR: a new target in resistance mediated by BCR/ABL-315I? I Haberbosch, A Rafiei, C Oancea, GO Ottmann, M Ruthardt, AA Mian Genes & cancer 7 (1-2), 36, 2016 | 6 | 2016 |
| PF-114, a novel selective Pan BCR/ABL inhibitor targets the T315I and suppress models of advanced Ph+ ALL A Mian, A Rafiei, A Metodieva, I Haberbosch, A Zeifman, I Titov, V Stroylov, ... Blood 122 (21), 3907, 2013 | 5 | 2013 |
| Subtractive interaction proteomics reveal a network of signaling pathways activated by an oncogenic transcription factor in acute myeloid leukemia N Guillen, M Wieske, A Otto, AA Mian, M Rokicki, C Guy, C Alvares, ... BioRxiv, 464958, 2018 | 4 | 2018 |
