P. Hemachandra Reddy
P. Hemachandra Reddy
Texas Tech Health Sciences Center
Verified email at - Homepage
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Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
M Manczak, TS Anekonda, E Henson, BS Park, J Quinn, PH Reddy
Human molecular genetics 15 (9), 1437-1449, 2006
Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
PH Reddy, MF Beal
Trends in molecular medicine 14 (2), 45-53, 2008
Mitochondrial dysfunction and oxidative stress in metabolic disorders—A step towards mitochondria based therapeutic strategies
JS Bhatti, GK Bhatti, PH Reddy
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (5 …, 2017
Role of glutamate and NMDA receptors in Alzheimer’s disease
R Wang, PH Reddy
Journal of Alzheimer's Disease 57 (4), 1041-1048, 2017
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for …
M Manczak, MJ Calkins, PH Reddy
Human molecular genetics 20 (13), 2495-2509, 2011
Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease
S Pugazhenthi, L Qin, PH Reddy
Biochimica et biophysica acta (BBA)-molecular basis of disease 1863 (5 …, 2017
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
MJ Calkins, M Manczak, P Mao, U Shirendeb, PH Reddy
Human molecular genetics 20 (23), 4515-4529, 2011
Is Alzheimer's disease a type 3 diabetes? A critical appraisal
R Kandimalla, V Thirumala, PH Reddy
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (5 …, 2017
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA
PH Reddy, M Williams, V Charles, L Garrett, L Pike-Buchanan, ...
Nature genetics 20 (2), 198-202, 1998
Mitochondria-targeted antioxidants protect against amyloid-β toxicity in Alzheimer's disease neurons
M Manczak, P Mao, MJ Calkins, A Cornea, AP Reddy, MP Murphy, ...
Journal of Alzheimer's Disease 20 (s2), S609-S631, 2010
Amyloid precursor protein‐mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease
PH Reddy
Journal of neurochemistry 96 (1), 1-13, 2006
Differential expression of oxidative phosphorylation genes in patients with Alzheimer’s disease: implications for early mitochondrial dysfunction and oxidative damage
M Manczak, BS Park, Y Jung, PH Reddy
Neuromolecular medicine 5, 147-162, 2004
Differential loss of synaptic proteins in Alzheimer's disease: implications for synaptic dysfunction
PH Reddy, G Mani, BS Park, J Jacques, G Murdoch, W Whetsell Jr, ...
Journal of Alzheimer's Disease 7 (2), 103-117, 2005
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and …
M Manczak, PH Reddy
Human molecular genetics 21 (11), 2538-2547, 2012
Polyglutamine-expanded huntingtin promotes sensitization of N-methyl-D-aspartate receptors via post-synaptic density 95
Y Sun, A Savanenin, PH Reddy, YF Liu
Journal of Biological Chemistry 276 (27), 24713-24718, 2001
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
PH Reddy, MF Beal
Brain Research Reviews 49 (3), 618-632, 2005
Abnormal mitochondrial dynamics and synaptic degeneration as early events in Alzheimer's disease: implications to mitochondria-targeted antioxidant therapeutics
PH Reddy, R Tripathi, Q Troung, K Tirumala, TP Reddy, V Anekonda, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (5), 639-649, 2012
Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage
U Shirendeb, AP Reddy, M Manczak, MJ Calkins, P Mao, DA Tagle, ...
Human molecular genetics 20 (7), 1438-1455, 2011
Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change …
PH Reddy, S McWeeney, BS Park, M Manczak, RV Gutala, D Partovi, ...
Human molecular genetics 13 (12), 1225-1240, 2004
Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
PH Reddy, TP Reddy, M Manczak, MJ Calkins, U Shirendeb, P Mao
Brain research reviews 67 (1-2), 103-118, 2011
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