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Hesham A M Gomaa
Hesham A M Gomaa
Faculty of Pharmacy, Jouf University, KSA
Verified email at ju.edu.sa
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Cited by
Cited by
Year
Design, synthesis, and biological evaluation of novel EGFR inhibitors containing 5-chloro-3-hydroxymethyl-indole-2-carboxamide scaffold with apoptotic antiproliferative activity
FAM Mohamed, HAM Gomaa, OM Hendawy, AT Ali, HS Farghaly, ...
Bioorganic Chemistry 112, 104960, 2021
502021
5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents
BGM Youssif, AM Mohamed, EEA Osman, OF Abou-Ghadir, DH Elnaggar, ...
European Journal of Medicinal Chemistry 177, 1-11, 2019
462019
Novel aryl carboximidamide and 3-aryl-1, 2, 4-oxadiazole analogues of naproxen as dual selective COX-2/15-LOX inhibitors: Design, synthesis and docking studies
BGM Youssif, MFA Mohamed, MM Al-Sanea, AH Moustafa, ...
Bioorganic chemistry 85, 577-584, 2019
452019
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives bearing 1, 3-thiazole moiety as novel anti-inflammatory EGFR inhibitors with cardiac …
SA Abdel-Aziz, ES Taher, P Lan, GF Asaad, HAM Gomaa, NA El-Koussi, ...
Bioorganic Chemistry 111, 104890, 2021
442021
Optimization and SAR investigation of novel 2, 3-dihydropyrazino [1, 2-a] indole-1, 4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and …
HAM Gomaa, ME Shaker, SI Alzarea, OM Hendawy, FAM Mohamed, ...
Bioorganic Chemistry 120, 105616, 2022
402022
Novel 1, 2, 4-triazole derivatives as apoptotic inducers targeting p53: Synthesis and antiproliferative activity
HAM Gomaa, HAM El-Sherief, S Hussein, AM Gouda, OIA Salem, ...
Bioorganic chemistry 105, 104369, 2020
372020
Design, synthesis and biological evaluation of new HDAC1 and HDAC2 inhibitors endowed with ligustrazine as a novel cap moiety
MM Al-Sanea, L Gotina, MFA Mohamed, D Grace Thomas Parambi, ...
Drug design, development and therapy, 497-508, 2020
372020
Design, synthesis, and antibacterial evaluation of new quinoline-1, 3, 4-oxadiazole and quinoline-1, 2, 4-triazole hybrids as potential inhibitors of DNA gyrase and …
HA Hofny, MFA Mohamed, HAM Gomaa, SA Abdel-Aziz, BGM Youssif, ...
Bioorganic Chemistry 112, 104920, 2021
362021
Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges
M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan, HAM Gomaa, ...
Polymers 15 (5), 1123, 2023
342023
Design and synthesis of new triarylimidazole derivatives as dual inhibitors of BRAF V600E /p38 αwith potential antiproliferative activity
AAM Bahaa G.M. Youssif , Ahmed M. Gouda , Amr H. Moustafa , Antar A ...
Journal of Molecular Structure 1253, 132218, 2021
34*2021
Discovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies
RA Mekheimer, SMR Allam, MA Al-Sheikh, MS Moustafa, SM Al-Mousawi, ...
Bioorganic Chemistry 121, 105693, 2022
272022
New 1, 3, 4‐oxadiazoles linked with the 1, 2, 3‐triazole moiety as antiproliferative agents targeting the EGFR tyrosine kinase
MA Mahmoud, AF Mohammed, OIA Salem, HAM Gomaa, BGM Youssif
Archiv der Pharmazie 355 (6), 2200009, 2022
252022
Design, synthesis, and antibacterial screening of some novel heteroaryl-based ciprofloxacin derivatives as DNA gyrase and topoisomerase IV inhibitors
LH Al-Wahaibi, AA Amer, AA Marzouk, HAM Gomaa, BGM Youssif, ...
Pharmaceuticals 14 (5), 399, 2021
242021
Structure-based design, synthesis and antiproliferative action of new quinazoline-4-one/chalcone hybrids as EGFR inhibitors
M Hisham, HA Hassan, HAM Gomaa, BGM Youssif, AM Hayallah, ...
Journal of Molecular Structure 1254, 132422, 2022
222022
Assessment of the chemo-preventive effects of various plant constituents against doxorubicin-induced toxicity in rats
HA Soliman, RR Ahmed, HA Gomaa, AT Ali
J Am Sci 10 (9), 153-164, 2014
182014
Cold-pressed raspberry seeds oil ameliorates high-fat diet triggered non-alcoholic fatty liver disease
O Hendawy, HAM Gomaa, S Hussein, SI Alzarea, S Qasim, ...
Saudi Pharmaceutical Journal 29 (11), 1303-1313, 2021
172021
Novel 1, 2, 4-oxadiazole/pyrrolidine hybrids as DNA gyrase and topoisomerase IV inhibitors with potential antibacterial activity
FOA Frejat, Y Cao, H Zhai, SA Abdel-Aziz, HAM Gomaa, BGM Youssif, ...
Arabian Journal of Chemistry 15 (1), 103538, 2022
162022
New quinoline/1, 2, 4-triazole hybrids as dual inhibitors of COX-2/5-LOX and inflammatory cytokines: Design, synthesis, and docking study
AM Mohassab, HA Hassan, D Abdelhamid, AM Gouda, HAM Gomaa, ...
Journal of Molecular Structure 1244, 130948, 2021
162021
Novel 1, 5-diaryl pyrazole-3-carboxamides as selective COX-2/sEH inhibitors with analgesic, anti-inflammatory, and lower cardiotoxicity effects
OM Hendawy, HAM Gomaa, SI Alzarea, MS Alshammari, FAM Mohamed, ...
Bioorganic Chemistry 116, 105302, 2021
112021
Discovery of new cyanopyridine/chalcone hybrids as dual inhibitors of EGFR/BRAFV600E with promising antiproliferative properties
HA Abou‐Zied, EAM Beshr, HAM Gomaa, YA Mostafa, BGM Youssif, ...
Archiv der Pharmazie 356 (4), 2200464, 2023
102023
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