| Chimeric antigen receptor therapy for cancer DM Barrett, N Singh, DL Porter, SA Grupp, CH June Annual review of medicine 65, 333-347, 2014 | 461 | 2014 |
| Ionizable lipid nanoparticle-mediated mRNA delivery for human CAR T cell engineering MM Billingsley, N Singh, P Ravikumar, R Zhang, CH June, MJ Mitchell Nano letters 20 (3), 1578-1589, 2020 | 340 | 2020 |
| Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies N Singh, J Perazzelli, SA Grupp, DM Barrett Science translational medicine 8 (320), 320ra3-320ra3, 2016 | 275 | 2016 |
| Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T-cell dysfunction N Singh, YG Lee, O Shestova, P Ravikumar, KE Hayer, SJ Hong, XM Lu, ... Cancer discovery 10 (4), 552-567, 2020 | 215 | 2020 |
| An NK-like CAR T cell transition in CAR T cell dysfunction CR Good, MA Aznar, S Kuramitsu, P Samareh, S Agarwal, G Donahue, ... Cell 184 (25), 6081-6100. e26, 2021 | 188 | 2021 |
| Immunotherapy for ovarian cancer: what's next? LE Kandalaft, DJ Powell Jr, N Singh, G Coukos Journal of Clinical Oncology 29 (7), 925, 2011 | 171 | 2011 |
| Monocyte lineage–derived IL-6 does not affect chimeric antigen receptor T-cell function N Singh, TJ Hofmann, Z Gershenson, BL Levine, SA Grupp, DT Teachey, ... Cytotherapy 19 (7), 867-880, 2017 | 152 | 2017 |
| Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy DM Barrett, N Singh, X Liu, S Jiang, CH June, SA Grupp, Y Zhao Cytotherapy 16 (5), 619-630, 2014 | 120 | 2014 |
| Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells N Singh, NV Frey, B Engels, DM Barrett, O Shestova, P Ravikumar, ... Nature medicine 27 (5), 842-850, 2021 | 105 | 2021 |
| CAR T cell therapy in acute lymphoblastic leukemia and potential for chronic lymphocytic leukemia N Singh, NV Frey, SA Grupp, SL Maude Current treatment options in oncology 17, 1-11, 2016 | 83 | 2016 |
| Nature of tumor control by permanently and transiently modified GD2 chimeric antigen receptor T cells in xenograft models of neuroblastoma N Singh, X Liu, J Hulitt, S Jiang, CH June, SA Grupp, DM Barrett, Y Zhao Cancer immunology research 2 (11), 1059-1070, 2014 | 79 | 2014 |
| Genome-editing technologies in adoptive T cell immunotherapy for cancer N Singh, J Shi, CH June, M Ruella Current hematologic malignancy reports 12, 522-529, 2017 | 76 | 2017 |
| The emergence of immunomodulation: combinatorial immunochemotherapy opportunities for the next decade LE Kandalaft, N Singh, JB Liao, A Facciabene, JS Berek, DJ Powell Jr, ... Gynecologic oncology 116 (2), 222-233, 2010 | 52 | 2010 |
| T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma N Singh, I Kulikovskaya, DM Barrett, G Binder-Scholl, B Jakobsen, ... Oncoimmunology 5 (1), e1040216, 2016 | 48 | 2016 |
| Interleukin 6 is not made by chimeric antigen receptor T cells and does not impact their function DM Barrett, N Singh, TJ Hofmann, Z Gershenson, SA Grupp Blood 128 (22), 654, 2016 | 35 | 2016 |
| Mechanisms of resistance to CAR T cell therapies N Singh, E Orlando, J Xu, J Xu, Z Binder, MKA Collins, DM O’Rourke, ... Seminars in cancer biology 65, 91-98, 2020 | 33 | 2020 |
| Modulation of CD22 protein expression in childhood leukemia by pervasive splicing aberrations: implications for CD22-directed immunotherapies S Zheng, E Gillespie, AS Naqvi, KE Hayer, Z Ang, M Torres-Diz, ... Blood cancer discovery 3 (2), 103-115, 2022 | 30 | 2022 |
| Antigen glycosylation regulates efficacy of CAR T cells targeting CD19 A Heard, JH Landmann, AR Hansen, A Papadopolou, YS Hsu, ME Selli, ... Nature communications 13 (1), 3367, 2022 | 28 | 2022 |
| Erythropoietic protoporphyria in an adult with sequential liver and hematopoietic stem cell transplantation: a case report AL Windon, R Tondon, N Singh, S Abu‐Gazala, DL Porter, JE Russell, ... American Journal of Transplantation 18 (3), 745-749, 2018 | 24 | 2018 |
| Antigen-specific depletion of CD4+ T cells by CAR T cells reveals distinct roles of higher- and lower-affinity TCRs during autoimmunity J Yi, AT Miller, AS Archambault, AJ Jones, TR Bradstreet, S Bandla, ... Science immunology 7 (76), eabo0777, 2022 | 23 | 2022 |
Carl JuneUniversity of PennsylvaniaVerified email at upenn.edu
