Structure of the Hsp110: Hsc70 nucleotide exchange machine JP Schuermann, J Jiang, J Cuellar, O Llorca, L Wang, LE Gimenez, S Jin, ... Molecular cell 31 (2), 232-243, 2008 | 269 | 2008 |
Modulation of the Hsp90 chaperone cycle by a stringent client protein OR Lorenz, L Freiburger, DA Rutz, M Krause, BK Zierer, S Alvira, ... Molecular cell 53 (6), 941-953, 2014 | 167 | 2014 |
Interaction of p53 with the CCT complex promotes protein folding and wild-type p53 activity AG Trinidad, PAJ Muller, J Cuellar, M Klejnot, M Nobis, JM Valpuesta, ... Molecular cell 50 (6), 805-817, 2013 | 154 | 2013 |
Structural characterization of the substrate transfer mechanism in Hsp70/Hsp90 folding machinery mediated by Hop S Alvira, J Cuéllar, A Röhl, S Yamamoto, H Itoh, C Alfonso, G Rivas, ... Nature communications 5 (1), 5484, 2014 | 145 | 2014 |
The structure of CCT–Hsc70NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin J Cuéllar, J Martín-Benito, SHW Scheres, R Sousa, F Moro, ... Nature structural & molecular biology 15 (8), 858-864, 2008 | 123 | 2008 |
Dynamics, flexibility, and allostery in molecular chaperonins L Skjærven, J Cuellar, A Martinez, JM Valpuesta FEBS letters 589 (19), 2522-2532, 2015 | 99 | 2015 |
Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor A Pena, K Gewartowski, S Mroczek, J Cuellar, A Szykowska, A Prokop, ... The EMBO journal 31 (6), 1605-1616, 2012 | 99 | 2012 |
PhLP3 modulates CCT-mediated actin and tubulin folding via ternary complexes with substrates PC Stirling, J Cuéllar, GA Alfaro, F El Khadali, CT Beh, JM Valpuesta, ... Journal of Biological Chemistry 281 (11), 7012-7021, 2006 | 96 | 2006 |
Clathrin-coat disassembly illuminates the mechanisms of Hsp70 force generation R Sousa, HS Liao, J Cuellar, S Jin, JM Valpuesta, AJ Jin, EM Lafer Nature structural & molecular biology 23 (9), 821-829, 2016 | 89 | 2016 |
Arc is a flexible modular protein capable of reversible self-oligomerization C Myrum, A Baumann, HJ Bustad, MI Flydal, V Mariaule, S Alvira, ... Biochemical Journal 468 (1), 145-158, 2015 | 81 | 2015 |
The architecture of the Schizosaccharomyces pombe CCR4-NOT complex M Ukleja, J Cuellar, A Siwaszek, JM Kasprzak, M Czarnocki-Cieciura, ... Nature communications 7 (1), 10433, 2016 | 63 | 2016 |
Structural and functional analysis of the role of the chaperonin CCT in mTOR complex assembly J Cuéllar, WG Ludlam, NC Tensmeyer, T Aoba, M Dhavale, C Santiago, ... Nature communications 10 (1), 2865, 2019 | 62 | 2019 |
Structures of the Gβ-CCT and PhLP1–Gβ-CCT complexes reveal a mechanism for G-protein β-subunit folding and Gβγ dimer assembly RL Plimpton, J Cuéllar, CWJ Lai, T Aoba, A Makaju, S Franklin, AD Mathis, ... Proceedings of the National Academy of Sciences 112 (8), 2413-2418, 2015 | 57 | 2015 |
Structural mechanism for tyrosine hydroxylase inhibition by dopamine and reactivation by Ser40 phosphorylation MT Bueno-Carrasco, J Cuéllar, MI Flydal, C Santiago, TA Kråkenes, ... Nature communications 13 (1), 74, 2022 | 48 | 2022 |
Programmed Cell Death Protein 5 Interacts with the Cytosolic Chaperonin Containing Tailless Complex Polypeptide 1 (CCT) to Regulate β-Tubulin Folding*♦ CM Tracy, AJ Gray, J Cuéllar, TS Shaw, AC Howlett, RM Taylor, JT Prince, ... Journal of Biological Chemistry 289 (7), 4490-4502, 2014 | 40 | 2014 |
Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif MS Eriksen, O Nikolaienko, EI Hallin, S Grødem, HJ Bustad, MI Flydal, ... The FEBS journal 288 (9), 2930-2955, 2021 | 36 | 2021 |
Structural insights into the chaperone activity of the 40-kDa heat shock protein DnaJ: binding and remodeling of a native substrate J Cuéllar, J Perales-Calvo, A Muga, JM Valpuesta, F Moro Journal of Biological Chemistry 288 (21), 15065-15074, 2013 | 34 | 2013 |
Chaperonin mechanisms: Multiple and (mis) understood? A Horovitz, TH Reingewertz, J Cuéllar, JM Valpuesta Annual review of biophysics 51 (1), 115-133, 2022 | 29 | 2022 |
The yeast THO complex forms a 5-subunit assembly that directly interacts with active chromatin K Gewartowski, J Cuéllar, A Dziembowski, JM Valpuesta Bioarchitecture 2 (4), 134-137, 2012 | 21 | 2012 |
Beyond the known functions of the CCR4‐NOT complex in gene expression regulatory mechanisms: new structural insights to unravel CCR4‐NOT mRNA processing machinery M Ukleja, JM Valpuesta, A Dziembowski, J Cuellar Bioessays 38 (10), 1048-1058, 2016 | 20 | 2016 |