Subnuclear compartmentalization of immunoglobulin loci during lymphocyte development ST Kosak, JA Skok, KL Medina, R Riblet, MM Le Beau, AG Fisher, ... Science 296 (5565), 158-162, 2002 | 859 | 2002 |
CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation V Narendra, PP Rocha, D An, R Raviram, JA Skok, EO Mazzoni, ... Science 347 (6225), 1017-1021, 2015 | 628 | 2015 |
Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene M Fuxa, J Skok, A Souabni, G Salvagiotto, E Roldan, M Busslinger Genes & development 18 (4), 411-422, 2004 | 473 | 2004 |
Locus' decontraction'and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene E Roldán, M Fuxa, W Chong, D Martinez, M Novatchkova, M Busslinger, ... Nature immunology 6 (1), 31-41, 2005 | 291 | 2005 |
Yin Yang 1 is a critical regulator of B-cell development H Liu, M Schmidt-Supprian, Y Shi, E Hobeika, N Barteneva, H Jumaa, ... Genes & development 21 (10), 1179-1189, 2007 | 288 | 2007 |
Capturing the onset of PRC2-mediated repressive domain formation O Oksuz, V Narendra, CH Lee, N Descostes, G LeRoy, R Raviram, ... Molecular cell 70 (6), 1149-1162. e5, 2018 | 251 | 2018 |
Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling K Johnson, T Hashimshony, CM Sawai, JMR Pongubala, JA Skok, ... Immunity 28 (3), 335-345, 2008 | 246 | 2008 |
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes JA Skok, KE Brown, V Azuara, ML Caparros, J Baxter, K Takacs, N Dillon, ... Nature immunology 2 (9), 848-854, 2001 | 240 | 2001 |
RNA interactions are essential for CTCF-mediated genome organization R Saldaña-Meyer, J Rodriguez-Hernaez, T Escobar, M Nishana, ... Molecular cell 76 (3), 412-422. e5, 2019 | 239 | 2019 |
DNA methylation disruption reshapes the hematopoietic differentiation landscape F Izzo, SC Lee, A Poran, R Chaligne, F Gaiti, B Gross, RR Murali, ... Nature genetics 52 (4), 378-387, 2020 | 221 | 2020 |
Epigenetic ontogeny of the Igk locus during B cell development M Goldmit, Y Ji, J Skok, E Roldan, S Jung, H Cedar, Y Bergman Nature immunology 6 (2), 198-203, 2005 | 193 | 2005 |
Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms J Mullenders, B Aranda-Orgilles, P Lhoumaud, M Keller, J Pae, K Wang, ... Journal of Experimental Medicine 212 (11), 1833-1850, 2015 | 173 | 2015 |
Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes JA Skok, R Gisler, M Novatchkova, D Farmer, W de Laat, M Busslinger Nature immunology 8 (4), 378-387, 2007 | 171 | 2007 |
CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci Y Fu, PP Rocha, VM Luo, R Raviram, Y Deng, EO Mazzoni, JA Skok Nature communications 7 (1), 11707, 2016 | 167 | 2016 |
RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci SL Hewitt, B Yin, Y Ji, J Chaumeil, K Marszalek, J Tenthorey, ... Nature immunology 10 (6), 655-664, 2009 | 162 | 2009 |
Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development J Skok, J Poudrier, D Gray The Journal of Immunology 163 (8), 4284-4291, 1999 | 138 | 1999 |
Association between the Igk and Igh immunoglobulin loci mediated by the 3′ Igk enhancer induces 'decontraction' of the Igh locus in pre–B cells SL Hewitt, D Farmer, K Marszalek, E Cadera, HE Liang, Y Xu, ... Nature immunology 9 (4), 396-404, 2008 | 137 | 2008 |
MED12 regulates HSC-specific enhancers independently of mediator kinase activity to control hematopoiesis B Aranda-Orgilles, R Saldaña-Meyer, E Wang, E Trompouki, A Fassl, ... Cell stem cell 19 (6), 784-799, 2016 | 122 | 2016 |
The RAG2 C terminus suppresses genomic instability and lymphomagenesis L Deriano, J Chaumeil, M Coussens, A Multani, YF Chou, ... Nature 471 (7336), 119-123, 2011 | 118 | 2011 |
Low-grade astrocytoma mutations in IDH1, P53, and ATRX cooperate to block differentiation of human neural stem cells via repression of SOX2 AS Modrek, D Golub, T Khan, D Bready, J Prado, C Bowman, J Deng, ... Cell reports 21 (5), 1267-1280, 2017 | 99 | 2017 |