| Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies F Hossain, AA Al-Khami, D Wyczechowska, C Hernandez, L Zheng, ... Cancer immunology research 3 (11), 1236-1247, 2015 | 448 | 2015 |
| Arginine metabolism in myeloid cells shapes innate and adaptive immunity PC Rodriguez, AC Ochoa, AA Al-Khami Frontiers in immunology 8, 93, 2017 | 254 | 2017 |
| l-Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells M Fletcher, ME Ramirez, RA Sierra, P Raber, P Thevenot, AA Al-Khami, ... Cancer research 75 (2), 275-283, 2015 | 252 | 2015 |
| Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells AA Al-Khami, L Zheng, L Del Valle, F Hossain, D Wyczechowska, ... Oncoimmunology 6 (10), e1344804, 2017 | 245 | 2017 |
| The stress-response sensor chop regulates the function and accumulation of myeloid-derived suppressor cells in tumors PT Thevenot, RA Sierra, PL Raber, AA Al-Khami, J Trillo-Tinoco, P Zarreii, ... Immunity 41 (3), 389-401, 2014 | 238 | 2014 |
| Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease P Kesarwani, AK Murali, AA Al-Khami, S Mehrotra Antioxidants & redox signaling 18 (12), 1497-1534, 2013 | 228 | 2013 |
| Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in … ML Salem, CM Díaz-Montero, AA Al-Khami, SA El-Naggar, O Naga, ... The Journal of Immunology 182 (4), 2030-2040, 2009 | 124 | 2009 |
| A quantitative increase in regulatory T cells controls development of vitiligo S Chatterjee, JM Eby, AA Al-Khami, M Soloshchenko, HK Kang, N Kaur, ... Journal of Investigative Dermatology 134 (5), 1285-1294, 2014 | 101 | 2014 |
| Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells ML Salem, AA Al-Khami, SA El-Naggar, CM Díaz-Montero, Y Chen, ... The journal of immunology 184 (4), 1737-1747, 2010 | 77 | 2010 |
| Priming of naive CD8+ T cells in the presence of IL-12 selectively enhances the survival of CD8+CD62Lhi cells and results in superior anti-tumor activity in a … CM Díaz-Montero, S El Naggar, A Al Khami, R El Naggar, AJ Montero, ... Cancer Immunology, Immunotherapy 57, 563-572, 2008 | 71 | 2008 |
| Pro-survival lipid sphingosine-1-phosphate metabolically programs T cells to limit anti-tumor activity P Chakraborty, SG Vaena, K Thyagarajan, S Chatterjee, A Al-Khami, ... Cell reports 28 (7), 1879-1893. e7, 2019 | 70 | 2019 |
| Energy metabolic pathways control the fate and function of myeloid immune cells AA Al-Khami, PC Rodriguez, AC Ochoa Journal of leukocyte biology 102 (2), 369-380, 2017 | 60 | 2017 |
| Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer AA Al-Khami, PC Rodriguez, AC Ochoa Oncoimmunology 5 (8), e1200771, 2016 | 58 | 2016 |
| A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice S Mehrotra, AA Al-Khami, J Klarquist, S Husain, O Naga, JM Eby, ... The Journal of Immunology 189 (4), 1627-1638, 2012 | 57 | 2012 |
| Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide ML Salem, AA Al-Khami, SA El-Nagaar, AAA Zidan, IM Al-Sharkawi, ... Cellular immunology 276 (1-2), 67-74, 2012 | 54 | 2012 |
| PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4+ T cell function MA Ghonim, K Pyakurel, SV Ibba, AA Al-Khami, J Wang, P Rodriguez, ... Journal of Translational Medicine 13, 1-12, 2015 | 49 | 2015 |
| Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer MA Ghonim, SV Ibba, AF Tarhuni, Y Errami, HH Luu, MJ Dean, ... Journal for immunotherapy of cancer 9 (1), 2021 | 45 | 2021 |
| Promoting thiol expression increases the durability of antitumor T-cell functions P Kesarwani, AA Al-Khami, G Scurti, K Thyagarajan, N Kaur, S Husain, ... Cancer research 74 (21), 6036-6047, 2014 | 45 | 2014 |
| T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules N Kaur, OS Naga, H Norell, AA Al-Khami, MJ Scheffel, NG Chakraborty, ... Cytokine 55 (2), 307-317, 2011 | 42 | 2011 |
| PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice MA Ghonim, K Pyakurel, SV Ibba, J Wang, P Rodriguez, AA Al-Khami, ... Clinical Science 129 (11), 951-962, 2015 | 39 | 2015 |
