| Structural basis of transcription initiation Y Zhang, Y Feng, S Chatterjee, S Tuske, MX Ho, E Arnold, RH Ebright Science 338 (6110), 1076-1080, 2012 | 348 | 2012 |
| The mechanism of RNA 5′ capping with NAD+, NADH and desphospho-CoA JG Bird, Y Zhang, Y Tian, N Panova, I Barvík, L Greene, M Liu, B Buckley, ... Nature 535 (7612), 444-447, 2016 | 201 | 2016 |
| Interactions between RNA polymerase and the “core recognition element” counteract pausing IO Vvedenskaya, H Vahedian-Movahed, JG Bird, JG Knoblauch, ... Science 344 (6189), 1285-1289, 2014 | 181 | 2014 |
| Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition W Lin, S Mandal, D Degen, Y Liu, YW Ebright, S Li, Y Feng, Y Zhang, ... Molecular Cell 66 (2), 169-179. e8, 2017 | 155 | 2017 |
| Antibacterial Nucleoside-Analog Inhibitor of Bacterial RNA Polymerase SI Maffioli, Y Zhang, D Degen, T Carzaniga, G Del Gatto, S Serina, ... Cell 169 (7), 1240-1248. e23, 2017 | 144 | 2017 |
| Structural basis of transcription activation Y Feng, Y Zhang, RH Ebright Science 352 (6291), 1330-1333, 2016 | 98 | 2016 |
| Two adjacent mutations on the dimer interface of SARS coronavirus 3C-like protease cause different conformational changes in crystal structure T Hu, Y Zhang, L Li, K Wang, S Chen, J Chen, J Ding, H Jiang, X Shen Virology 388 (2), 324-334, 2009 | 93 | 2009 |
| Transcription inhibition by the depsipeptide antibiotic salinamide A D Degen, Y Feng, Y Zhang, KY Ebright, YW Ebright, M Gigliotti, ... eLife 3, e02451, 2014 | 81 | 2014 |
| GE23077 binds to the RNA polymerase ‘i’and ‘i+ 1’sites and prevents the binding of initiating nucleotides Y Zhang, D Degen, MX Ho, E Sineva, KY Ebright, YW Ebright, V Mekler, ... Elife 3, e02450, 2014 | 77 | 2014 |
| CapZyme-seq comprehensively defines promoter-sequence determinants for RNA 5′ capping with NAD+ IO Vvedenskaya, JG Bird, Y Zhang, Y Zhang, X Jiao, I Barvík, L Krásný, ... Molecular cell 70 (3), 553-564. e9, 2018 | 73 | 2018 |
| Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity D Ye, Y Zhang, F Wang, M Zheng, X Zhang, X Luo, X Shen, H Jiang, H Liu Bioorganic & medicinal chemistry 18 (5), 1773-1782, 2010 | 72 | 2010 |
| Farnesoid X receptor induces GLUT4 expression through FXR response element in the GLUT4 promoter H Shen, Y Zhang, H Ding, X Wang, L Chen, H Jiang, X Shen Cellular Physiology and Biochemistry 22 (1-4), 001-014, 2008 | 70 | 2008 |
| Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection JT Winkelman, IO Vvedenskaya, Y Zhang, Y Zhang, JG Bird, DM Taylor, ... Science 351 (6277), 1090-1093, 2016 | 66 | 2016 |
| Hyrtiosal, a PTP1B inhibitor from the marine sponge Hyrtios erectus, shows extensive cellular effects on PI3K/AKT activation, glucose transport, and TGFβ/Smad2 signaling T Sun, Q Wang, Z Yu, Y Zhang, Y Guo, K Chen, X Shen, H Jiang Chembiochem 8 (2), 187-193, 2007 | 63 | 2007 |
| S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton C Zhang, N Yang, C Yang, H Ding, C Luo, Y Zhang, M Wu, X Zhang, ... PloS one 4 (3), e4881, 2009 | 61 | 2009 |
| A sesquiterpene quinone, dysidine, from the sponge Dysidea villosa, activates the insulin pathway through inhibition of PTPases Y Zhang, Y Li, Y Guo, H Jiang, X Shen Acta pharmacologica Sinica 30 (3), 333-345, 2009 | 61 | 2009 |
| A novel sesquiterpene quinone from Hainan sponge Dysidea villosa Y Li, Y Zhang, X Shen, YW Guo Bioorganic & medicinal chemistry letters 19 (2), 390-392, 2009 | 61 | 2009 |
| Structural basis for transcription initiation by bacterial ECF σ factors L Li, C Fang, N Zhuang, T Wang, Y Zhang Nature communications 10 (1), 1-14, 2019 | 55 | 2019 |
| Deoxyelephantopin inhibits cancer cell proliferation and functions as a selective partial agonist against PPARγ G Zou, Z Gao, J Wang, Y Zhang, H Ding, J Huang, L Chen, Y Guo, ... Biochemical pharmacology 75 (6), 1381-1392, 2008 | 54 | 2008 |
| Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism Z Lin, Y Zhang, Y Zhang, H Shen, L Hu, H Jiang, X Shen Biochemical pharmacology 76 (10), 1251-1262, 2008 | 52 | 2008 |
Richard H. EbrightBoard of Governors Professor of Chemistry and Chemical Biology, Rutgers UniversityVerified email at waksman.rutgers.edu
