| The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention JP Alao Molecular cancer 6, 1-16, 2007 | 1001 | 2007 |
| Histone deacetylase inhibitor trichostatin A represses estrogen receptor α-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma … JP Alao, EWF Lam, S Ali, L Buluwela, W Bordogna, P Lockey, ... Clinical Cancer Research 10 (23), 8094-8104, 2004 | 152 | 2004 |
| Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells JP Alao, AV Stavropoulou, EWF Lam, R Charles Coombes, DM Vigushin Molecular cancer 5, 1-11, 2006 | 119 | 2006 |
| Plasma pharmacokinetics and metabolism of the histone deacetylase inhibitor trichostatin a after intraperitoneal administration to mice L Sanderson, GW Taylor, EO Aboagye, JP Alao, JR Latigo, RC Coombes, ... Drug metabolism and disposition 32 (10), 1132-1138, 2004 | 115 | 2004 |
| ICI182, 780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor α from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer … R Varshochi, F Halim, A Sunters, JP Alao, PA Madureira, SM Hart, S Ali, ... Journal of Biological Chemistry 280 (5), 3185-3196, 2005 | 96 | 2005 |
| The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines JP Alao, SC Gamble, AV Stavropoulou, KM Pomeranz, EWF Lam, ... Molecular Cancer 5, 1-11, 2006 | 86 | 2006 |
| In vivo biological activity of the histone deacetylase inhibitor LAQ824 is detectable with 3′-deoxy-3′-[18F] fluorothymidine positron emission tomography J Leyton, JP Alao, M Da Costa, AV Stavropoulou, JR Latigo, M Perumal, ... Cancer Research 66 (15), 7621-7629, 2006 | 84 | 2006 |
| Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors C Dyrager, LN Mollers, LK Kjall, JP Alao, P Dinér, FK Wallner, ... Journal of medicinal chemistry 54 (20), 7427-7431, 2011 | 67 | 2011 |
| Preparation of 3-Substituted-1-Isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amines as RET Kinase Inhibitors P Dinér, JP Alao, J Söderlund, P Sunnerhagen, M Grøtli Journal of Medicinal Chemistry 55 (10), 4872-4876, 2012 | 63 | 2012 |
| T: G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif MJ Lucey, D Chen, J Lopez-Garcia, SM Hart, F Phoenix, R Al-Jehani, ... Nucleic acids research 33 (19), 6393-6404, 2005 | 59 | 2005 |
| The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation JP Alao, P Sunnerhagen Radiation Oncology 4, 1-7, 2009 | 56 | 2009 |
| Role of glycogen synthase kinase 3 beta (GSK3β) in mediating the cytotoxic effects of the histone deacetylase inhibitor trichostatin A (TSA) in MCF-7 breast cancer cells JP Alao, AV Stavropoulou, EWF Lam, RC Coombes Molecular cancer 5, 1-6, 2006 | 53 | 2006 |
| Flemingins G–O, Cytotoxic and Antioxidant Constituents of the Leaves of Flemingia grahamiana I Gumula, JP Alao, IO Ndiege, P Sunnerhagen, A Yenesew, M Erdélyi Journal of Natural Products 77 (9), 2060-2067, 2014 | 44 | 2014 |
| Antiplasmodial quinones from Pentas longiflora and Pentas lanceolata M Endale, JP Alao, HM Akala, NK Rono, FL Eyase, S Derese, A Ndakala, ... Planta medica 78 (01), 31-35, 2012 | 38 | 2012 |
| The nuclear oxysterol receptor LXRα is expressed in the normal human breast and in breast cancer DM Vigushin, Y Dong, L Inman, N Peyvandi, JP Alao, C Sun, S Ali, ... Medical Oncology 21, 123-131, 2004 | 37 | 2004 |
| Anthraquinones of the Roots of Pentas micrantha M Endale, A Ekberg, JP Alao, HM Akala, A Ndakala, P Sunnerhagen, ... Molecules 18 (1), 311-321, 2012 | 36 | 2012 |
| Rad3 and Sty1 function in Schizosaccharomyces pombe: an integrated response to DNA damage and environmental stress? JP Alao, P Sunnerhagen Molecular microbiology 68 (2), 246-254, 2008 | 34 | 2008 |
| Cytotoxic Quinones from the Roots of Aloe dawei N Abdissa, M Induli, P Fitzpatrick, JP Alao, P Sunnerhagen, G Landberg, ... Molecules 19 (3), 3264-3273, 2014 | 28 | 2014 |
| Structure–activity relationships of aryloxyalkanoic acid hydroxyamides as potent inhibitors of histone deacetylase CM Marson, T Mahadevan, J Dines, S Sengmany, JM Morrell, JP Alao, ... Bioorganic & medicinal chemistry letters 17 (1), 136-141, 2007 | 27 | 2007 |
| Stereodefined and polyunsaturated inhibitors of histone deacetylase based on (2E, 4E)-5-arylpenta-2, 4-dienoic acid hydroxyamides CM Marson, N Serradji, AS Rioja, SP Gastaud, JP Alao, RC Coombes, ... Bioorganic & medicinal chemistry letters 14 (10), 2477-2481, 2004 | 26 | 2004 |
Per SunnerhagenUniversity of Gothenburg, Department of Chemistry and Molecular Biologyبريد إلكتروني تم التحقق منه على cmb.gu.se
