Markos Leggas
Markos Leggas
Professor of Pharmaceutical Sciences, University of Kentucky
Verified email at uky.edu
Title
Cited by
Cited by
Year
Mrp4 confers resistance to topotecan and protects the brain from chemotherapy
M Leggas, M Adachi, GL Scheffer, D Sun, P Wielinga, G Du, KE Mercer, ...
Molecular and cellular biology 24 (17), 7612-7621, 2004
4502004
Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice
M Assem, EG Schuetz, M Leggas, D Sun, K Yasuda, G Reid, N Zelcer, ...
Journal of Biological Chemistry 279 (21), 22250-22257, 2004
2692004
Gefitinib enhances the antitumor activity and oral bioavailability of irinotecan in mice
CF Stewart, M Leggas, JD Schuetz, JC Panetta, PJ Cheshire, J Peterson, ...
Cancer research 64 (20), 7491-7499, 2004
2092004
Stable RNA nanoparticles as potential new generation drugs for cancer therapy
Y Shu, F Pi, A Sharma, M Rajabi, F Haque, D Shu, M Leggas, BM Evers, ...
Advanced drug delivery reviews 66, 74-89, 2014
1892014
Sunitinib malate for the treatment of metastatic renal cell carcinoma and gastrointestinal stromal tumors
VR Adams, M Leggas
Clinical therapeutics 29 (7), 1338-1353, 2007
1862007
Development of idarubicin and doxorubicin solid lipid nanoparticles to overcome Pgp-mediated multiple drug resistance in leukemia
P Ma, X Dong, CL Swadley, A Gupte, M Leggas, HC Ledebur, RJ Mumper
Journal of biomedical nanotechnology 5 (2), 151-161, 2009
1592009
Gefitinib modulates the function of multiple ATP-binding cassette transporters in vivo
M Leggas, JC Panetta, Y Zhuang, JD Schuetz, B Johnston, F Bai, ...
Cancer research 66 (9), 4802-4807, 2006
1562006
Biodistribution and bioimaging studies of hybrid paclitaxel nanocrystals: lessons learned of the EPR effect and image-guided drug delivery
CP Hollis, HL Weiss, M Leggas, BM Evers, RA Gemeinhart, T Li
Journal of Controlled Release 172 (1), 12-21, 2013
1312013
Topotecan combination chemotherapy in two new rodent models of retinoblastoma
NA Laurie, JK Gray, J Zhang, M Leggas, M Relling, M Egorin, C Stewart, ...
Clinical Cancer Research 11 (20), 7569-7578, 2005
1112005
Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution
K Takenaka, JA Morgan, GL Scheffer, M Adachi, CF Stewart, D Sun, ...
Cancer research 67 (14), 6965-6972, 2007
1092007
Morphine versus clonidine for neonatal abstinence syndrome
HS Bada, T Sithisarn, J Gibson, K Garlitz, R Caldwell, G Capilouto, Y Li, ...
Pediatrics 135 (2), e383-e391, 2015
522015
Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents
NR Penthala, VN Sonar, J Horn, M Leggas, JSKB Yadlapalli, PA Crooks
MedChemComm 4 (7), 1073-1078, 2013
412013
The mathematics of suspensions: Kac walks and asymptotic analyticity
EC Eckstein, JA Goldstein, M Leggas
Proceedings of the Fourth Mississippi State Conference on Difference …, 1999
391999
Nanoparticles containing anti-inflammatory agents as chemotherapy adjuvants: optimization and in vitro characterization
X Lu, MD Howard, M Mazik, J Eldridge, JJ Rinehart, M Jay, M Leggas
The AAPS journal 10 (1), 133-140, 2008
382008
Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice
JA Morgan, SB Cheepala, Y Wang, G Neale, M Adachi, D Nachagari, ...
Journal of Biological Chemistry 287 (18), 14456-14466, 2012
372012
Microbore HPLC method with online microdialysis for measurement of topotecan lactone and carboxylate in murine CSF
M Leggas, Y Zhuang, J Welden, Z Self, CM Waters, CF Stewart
Journal of pharmaceutical sciences 93 (9), 2284-2295, 2004
372004
Immunohistochemical detection of multidrug-resistant protein expression in retinoblastoma treated by primary enucleation
MW Wilson, CH Fraga, CE Fuller, C Rodriguez-Galindo, J Mancini, ...
Investigative ophthalmology & visual science 47 (4), 1269-1273, 2006
342006
Relation between Irofulven (MGI-114) systemic exposure and tumor response in human solid tumor xenografts
M Leggas, CF Stewart, MH Woo, M Fouladi, PJ Cheshire, JK Peterson, ...
Clinical cancer research 8 (9), 3000-3007, 2002
332002
Progesterone acts via progesterone receptors A and B to regulate breast cancer resistance protein expression
M Vore, M Leggas
Molecular pharmacology 73 (3), 613-615, 2008
322008
Cytotoxic Indolocarbazoles from Actinomadura melliaura ATCC 39691
KA Shaaban, SI Elshahawi, X Wang, J Horn, MK Kharel, M Leggas, ...
Journal of natural products 78 (7), 1723-1729, 2015
282015
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