Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1) M Marzec, Q Zhang, A Goradia, PN Raghunath, X Liu, M Paessler, ... Proceedings of the National Academy of Sciences 105 (52), 20852-20857, 2008 | 787 | 2008 |
GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum M Marzec, D Eletto, Y Argon Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (3), 774-787, 2012 | 442 | 2012 |
STAT3-and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes Q Zhang, HY Wang, M Marzec, PN Raghunath, T Nagasawa, MA Wasik Proceedings of the National Academy of Sciences 102 (19), 6948-6953, 2005 | 302 | 2005 |
Nucleophosmin/anaplastic lymphoma kinase (NPM/ALK) oncoprotein induces the T regulatory cell phenotype by activating STAT3 M Kasprzycka, M Marzec, X Liu, Q Zhang, MA Wasik Proceedings of the National Academy of Sciences 103 (26), 9964-9969, 2006 | 174 | 2006 |
Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity M Marzec, M Kasprzycka, R Lai, AB Gladden, P Wlodarski, E Tomczak, ... Blood 108 (5), 1744-1750, 2006 | 170 | 2006 |
Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway M Marzec, M Kasprzycka, X Liu, M El-Salem, K Halasa, PN Raghunath, ... Oncogene 26 (38), 5606-5614, 2007 | 131 | 2007 |
Oncogenic tyrosine kinase NPM/ALK induces activation of the MEK/ERK signaling pathway independently of c-Raf M Marzec, M Kasprzycka, X Liu, PN Raghunath, P Wlodarski, MA Wasik Oncogene 26 (6), 813-821, 2007 | 107 | 2007 |
Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3 M Marzec, M Kasprzycka, A Ptasznik, P Wlodarski, Q Zhang, N Odum, ... Laboratory investigation 85 (12), 1544-1554, 2005 | 105 | 2005 |
Differential effects of interleukin-2 and interleukin-15 versus interleukin-21 on CD4+ cutaneous T-cell lymphoma cells M Marzec, K Halasa, M Kasprzycka, M Wysocka, X Liu, JW Tobias, ... Cancer research 68 (4), 1083-1091, 2008 | 98 | 2008 |
Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal … P Wlodarski, M Kasprzycka, X Liu, M Marzec, ES Robertson, A Slupianek, ... Cancer research 65 (17), 7800-7808, 2005 | 88 | 2005 |
IL-2– and IL-15–induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes M Marzec, X Liu, M Kasprzycka, A Witkiewicz, PN Raghunath, M El-Salem, ... Blood, The Journal of the American Society of Hematology 111 (4), 2181-2189, 2008 | 81 | 2008 |
Endoplasmic reticulum chaperone glucose-regulated protein 94 is essential for proinsulin handling SM Ghiasi, T Dahlby, C Hede Andersen, L Haataja, S Petersen, ... Diabetes 68 (4), 747-760, 2019 | 70 | 2019 |
γc-signaling cytokines induce a regulatory T cell phenotype in malignant CD4+ T lymphocytes M Kasprzycka, Q Zhang, A Witkiewicz, M Marzec, M Potoczek, X Liu, ... The Journal of Immunology 181 (4), 2506-2512, 2008 | 66 | 2008 |
Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells M Marzec, X Liu, M Wysocka, AH Rook, N Odum, MA Wasik PloS one 6 (9), e24849, 2011 | 65 | 2011 |
Peroxisome proliferator-activated receptor γ promotes lymphocyte survival through its actions on cellular metabolic activities SH Jo, C Yang, Q Miao, M Marzec, MA Wasik, P Lu, YL Wang The Journal of Immunology 177 (6), 3737-3745, 2006 | 60 | 2006 |
Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes M Kasprzycka, M Majewski, ZJ Wang, A Ptasznik, M Wysocka, Q Zhang, ... The American journal of pathology 168 (5), 1631-1641, 2006 | 52 | 2006 |
Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders M El-Salem, PN Raghunath, M Marzec, P Wlodarski, D Tsai, E Hsi, ... Laboratory Investigation 87 (1), 29-39, 2007 | 48 | 2007 |
Oncogenic kinase NPM/ALK induces expression of HIF1α mRNA M Marzec, X Liu, W Wong, Y Yang, T Pasha, K Kantekure, P Zhang, ... Oncogene 30 (11), 1372-1378, 2011 | 46 | 2011 |
Anaplastic lymphoma kinase (ALK)-induced malignancies: novel mechanisms of cell transformation and potential therapeutic approaches MA Wasik, Q Zhang, M Marzec, M Kasprzycka, HY Wang, X Liu Seminars in oncology 36, S27-S35, 2009 | 43 | 2009 |
PU. 1 activates transcription of SHP-1 gene in hematopoietic cells P Wlodarski, Q Zhang, X Liu, M Kasprzycka, M Marzec, MA Wasik Journal of biological chemistry 282 (9), 6316-6323, 2007 | 37 | 2007 |