| A new asymmetric Wacker-type cyclization and tandem cyclization promoted by Pd (II)-spiro bis (isoxazoline) catalyst MA Arai, M Kuraishi, T Arai, H Sasai Journal of the American Chemical Society 123 (12), 2907-2908, 2001 | 246 | 2001 |
| Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space Y Kim, MA Arai, T Arai, JO Lamenzo, EF Dean, N Patterson, PA Clemons, ... Journal of the American Chemical Society 126 (45), 14740-14745, 2004 | 160 | 2004 |
| Naturally occurring small‐molecule inhibitors of hedgehog/GLI‐mediated transcription T Hosoya, MA Arai, T Koyano, T Kowithayakorn, M Ishibashi Chembiochem 9 (7), 1082-1092, 2008 | 152 | 2008 |
| Design and synthesis of the first spiro bis (isoxazoline) derivatives as asymmetric ligands MA Arai, T Arai, H Sasai Organic Letters 1 (11), 1795-1797, 1999 | 126 | 1999 |
| The first enantioselective intramolecular aminocarbonylation of alkenes promoted by Pd (II)-spiro bis (isoxazoline) catalyst T Shinohara, MA Arai, K Wakita, T Arai, H Sasai Tetrahedron letters 44 (4), 711-714, 2003 | 91 | 2003 |
| Terpenoids and a Flavonoid Glycoside from Acacia pennata Leaves as Hedgehog/GLI-Mediated Transcriptional Inhibitors Y Rifai, MA Arai, T Koyano, T Kowithayakorn, M Ishibashi Journal of natural products 73 (5), 995-997, 2010 | 87 | 2010 |
| Development of chiral spiro ligands for metal-catalyzed asymmetric reactions GB Bajracharya, MA Arai, PS Koranne, T Suzuki, S Takizawa, H Sasai Bulletin of the Chemical Society of Japan 82 (3), 285-302, 2009 | 87 | 2009 |
| Catalytic Asymmetric Synthesis of Mixed 3, 3′‐Bisindoles and Their Evaluation as Wnt Signaling Inhibitors T Arai, Y Yamamoto, A Awata, K Kamiya, M Ishibashi, MA Arai Angewandte Chemie International Edition 52 (9), 2486-2490, 2013 | 85 | 2013 |
| Hedgehog/GLI-mediated transcriptional inhibitors from Zizyphus cambodiana MA Arai, C Tateno, T Hosoya, T Koyano, T Kowithayakorn, M Ishibashi Bioorganic & medicinal chemistry 16 (21), 9420-9424, 2008 | 75 | 2008 |
| New Hedgehog/GLI signaling inhibitors from Excoecaria agallocha Y Rifai, MA Arai, SK Sadhu, F Ahmed, M Ishibashi Bioorganic & medicinal chemistry letters 21 (2), 718-722, 2011 | 66 | 2011 |
| Enantioselective synthesis of α-methylene-γ-butyrolactones using chiral Pd (II)-SPRIX catalyst C Muthiah, MA Arai, T Shinohara, T Arai, S Takizawa, H Sasai Tetrahedron letters 44 (28), 5201-5204, 2003 | 62 | 2003 |
| Synthesis, determination of stereochemistry, and evaluation of new bisindole alkaloids from the myxomycete Arcyria ferruginea: An approach for Wnt signal inhibitor K Kaniwa, MA Arai, X Li, M Ishibashi Bioorganic & medicinal chemistry letters 17 (15), 4254-4257, 2007 | 58 | 2007 |
| Calotropin: A Cardenolide from Calotropis gigantea that Inhibits Wnt Signaling by Increasing Casein Kinase 1α in Colon Cancer Cells HY Park, K Toume, MA Arai, SK Sadhu, F Ahmed, M Ishibashi Chembiochem 15 (6), 872-878, 2014 | 56 | 2014 |
| Cycloartane Triterpenes Isolated from Combretum quadrangulare in a Screening Program for Death-Receptor Expression Enhancing Activity K Toume, T Nakazawa, T Ohtsuki, MA Arai, T Koyano, T Kowithayakorn, ... Journal of natural products 74 (2), 249-255, 2011 | 51 | 2011 |
| Constituents of Amoora cucullata with TRAIL resistance-overcoming activity F Ahmed, K Toume, SK Sadhu, T Ohtsuki, MA Arai, M Ishibashi Organic & Biomolecular Chemistry 8 (16), 3696-3703, 2010 | 50 | 2010 |
| The Ministry of Labor sponsored grant for the prevention of work-related illness, FY 1999 report T Shimomitsu, T Haratani, K Nakamura, M Kato Tokyo Medical University, Tokyo, 2000 | 49 | 2000 |
| New hedgehog/GLI-signaling inhibitors from Adenium obesum MA Arai, C Tateno, T Koyano, T Kowithayakorn, S Kawabe, M Ishibashi Organic & Biomolecular Chemistry 9 (4), 1133-1139, 2011 | 48 | 2011 |
| 9-Hydroxycanthin-6-one, a β-Carboline Alkaloid from Eurycoma longifolia, Is the First Wnt Signal Inhibitor through Activation of Glycogen Synthase Kinase 3β … K Ohishi, K Toume, MA Arai, T Koyano, T Kowithayakorn, T Mizoguchi, ... Journal of natural products 78 (5), 1139-1146, 2015 | 47 | 2015 |
| Cycloartane triterpenes and ingol diterpenes isolated from Euphorbia neriifolia in a screening program for death-receptor expression-enhancing activity K Toume, T Nakazawa, T Hoque, T Ohtsuki, MA Arai, T Koyano, ... Planta medica 78 (12), 1370-1377, 2012 | 46 | 2012 |
| Group. 2018. Baloxavir marboxil for uncomplicated influenza in adults and adolescents FG Hayden, N Sugaya, N Hirotsu, N Lee, MD de Jong, AC Hurt, T Ishida, ... N Engl J Med 379, 913-923, 0 | 44 | |
