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Alejandro Pezzulo
Alejandro Pezzulo
Assistant Professor, Pulmonary and Critical Care Medicine, University of Iowa Carver College of
Verified email at uiowa.edu
Title
Cited by
Cited by
Year
Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung
AA Pezzulo, XX Tang, MJ Hoegger, MH Abou Alaiwa, S Ramachandran, ...
Nature 487 (7405), 109-113, 2012
9432012
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs
CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ...
Science 321 (5897), 1837-1841, 2008
8782008
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth
DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ...
Science translational medicine 2 (29), 29ra31-29ra31, 2010
5702010
The air-liquid interface and use of primary cell cultures are important to recapitulate the transcriptional profile of in vivo airway epithelia
AA Pezzulo, TD Starner, TE Scheetz, GL Traver, AE Tilley, BG Harvey, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (1 …, 2011
3972011
Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia
JH Chen, DA Stoltz, PH Karp, SE Ernst, AA Pezzulo, TO Moninger, ...
Cell 143 (6), 911-923, 2010
2662010
Human and murine paraoxonase 1 are host modulators of Pseudomonas aeruginosa quorum-sensing
EA Ozer, A Pezzulo, DM Shih, C Chun, C Furlong, AJ Lusis, ...
FEMS microbiology letters 253 (1), 29-37, 2005
2592005
The ΔF508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis–Like Disease in Pigs
LS Ostedgaard, DK Meyerholz, JH Chen, AA Pezzulo, PH Karp, ...
Science translational medicine 3 (74), 74ra24-74ra24, 2011
2342011
Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children
DK Meyerholz, DA Stoltz, E Namati, S Ramachandran, AA Pezzulo, ...
American journal of respiratory and critical care medicine 182 (10), 1251-1261, 2010
2022010
Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
ME Ortiz, A Thurman, AA Pezzulo, MR Leidinger, JA Klesney-Tait, ...
EBioMedicine 60, 2020
1772020
Pathology of gastrointestinal organs in a porcine model of cystic fibrosis
DK Meyerholz, DA Stoltz, AA Pezzulo, MJ Welsh
The American journal of pathology 176 (3), 1377-1389, 2010
1772010
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs
DA Stoltz, T Rokhlina, SE Ernst, AA Pezzulo, LS Ostedgaard, PH Karp, ...
The Journal of clinical investigation 123 (6), 2685-2693, 2013
1452013
Glucose depletion in the airway surface liquid is essential for sterility of the airways
AA Pezzulo, J Gutiérrez, KS Duschner, KS McConnell, PJ Taft, SE Ernst, ...
PloS one 6 (1), e16166, 2011
1342011
Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth
MP Rogan, LR Reznikov, AA Pezzulo, ND Gansemer, M Samuel, ...
Proceedings of the National Academy of Sciences 107 (47), 20571-20575, 2010
1222010
Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study
MH Abou Alaiwa, AM Beer, AA Pezzulo, JL Launspach, RA Horan, ...
Journal of cystic fibrosis 13 (4), 373-377, 2014
932014
Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions
D Lorentzen, L Durairaj, AA Pezzulo, Y Nakano, J Launspach, DA Stoltz, ...
Free Radical Biology and Medicine 50 (9), 1144-1150, 2011
902011
Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19
LYR Wong, J Zheng, K Wilhelmsen, K Li, ME Ortiz, NJ Schnicker, ...
Nature 605 (7908), 146-151, 2022
852022
Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass
A Uc, AK Olivier, MA Griffin, DK Meyerholz, J Yao, M Abu-El-Haija, ...
Clinical science 128 (2), 131-142, 2015
732015
Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis
EH Chang, AA Pezzulo, DK Meyerholz, AE Potash, TJ Wallen, ...
The Laryngoscope 122 (9), 1898-1905, 2012
732012
Quantitative chest CT assessment of small airways disease in post-acute SARS-CoV-2 infection
JL Cho, R Villacreses, P Nagpal, J Guo, AA Pezzulo, AL Thurman, ...
Radiology 304 (1), 185-192, 2022
722022
Effect of vitamin D 3 on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial
LGV Buonfiglio, M Cano, AA Pezzulo, OGV Calderon, J Zabner, AK Gerke, ...
BMJ open respiratory research 4 (1), e000211, 2017
572017
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