Associate Professor J. Shaun Lott
Associate Professor J. Shaun Lott
School of Biological Sciences, University of Auckland
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A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
SL Kendall, M Withers, CN Soffair, NJ Moreland, S Gurcha, B Sidders, ...
Molecular microbiology 65 (3), 684-699, 2007
Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2
SL Kendall, P Burgess, R Balhana, M Withers, A Ten Bokum, JS Lott, ...
Microbiology 156 (Pt 5), 1362, 2010
The BC component of ABC toxins is an RHS-repeat-containing protein encapsulation device
JN Busby, S Panjikar, MJ Landsberg, MRH Hurst, JS Lott
Nature 501 (7468), 547-550, 2013
The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology
TC Terwilliger, MS Park, GS Waldo, J Berendzen, LW Hung, CY Kim, ...
Tuberculosis 83 (4), 223-249, 2003
Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation
A Heikal, Y Nakatani, E Dunn, MR Weimar, CL Day, EN Baker, JS Lott, ...
Molecular microbiology 91 (5), 950-964, 2014
The Structure of MbtI from Mycobacterium tuberculosis, the First Enzyme in the Biosynthesis of the Siderophore Mycobactin, Reveals It To Be a Salicylate Synthase
AJ Harrison, M Yu, T Gårdenborg, M Middleditch, RJ Ramsay, EN Baker, ...
Journal of bacteriology 188 (17), 6081-6091, 2006
3D structure of the Yersinia entomophaga toxin complex and implications for insecticidal activity
MJ Landsberg, SA Jones, R Rothnagel, JN Busby, SDG Marshall, ...
Proceedings of the National Academy of Sciences 108 (51), 20544-20549, 2011
A flexible and economical medium-throughput strategy for protein production and crystallization
N Moreland, R Ashton, HM Baker, I Ivanovic, S Patterson, VL Arcus, ...
Acta Crystallographica Section D: Biological Crystallography 61 (10), 1378-1385, 2005
The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II …
CJ Webby, HM Baker, JS Lott, EN Baker, EJ Parker
Journal of Molecular Biology 354 (4), 927-939, 2005
The TB structural genomics consortium: providing a structural foundation for drug discovery
CW Goulding, M Apostol, DH Anderson, HS Gill, CV Smith, MR Kuo, ...
Current Drug Targets-Infectious Disorders 2 (2), 121-141, 2002
Crystal Structure of AhpE from Mycobacterium tuberculosis, a 1-Cys peroxiredoxin
S Li, NA Peterson, MY Kim, CY Kim, LW Hung, M Yu, T Lekin, ...
Journal of molecular biology 346 (4), 1035-1046, 2005
Structural analysis of Chi1 chitinase from Yen-Tc: the multisubunit insecticidal ABC toxin complex of Yersinia entomophaga
JN Busby, MJ Landsberg, RM Simpson, SA Jones, B Hankamer, ...
Journal of molecular biology 415 (2), 359-371, 2012
Structure of a eukaryotic nonribosomal peptide synthetase adenylation domain that activates a large hydroxamate amino acid in siderophore biosynthesis
TV Lee, LJ Johnson, RD Johnson, A Koulman, GA Lane, JS Lott, VL Arcus
Journal of Biological Chemistry 285 (4), 2415-2427, 2010
Using secretion to solve a solubility problem: high-yield expression in Escherichia coli and purification of the bacterial glycoamidase PNGase F
T Loo, ML Patchett, GE Norris, JS Lott
Protein expression and purification 24 (1), 90-98, 2002
A new Gateway® vector and expression protocol for fast and efficient recombinant protein expression in Mycobacterium smegmatis
RM Goldstone, NJ Moreland, G Bashiri, EN Baker, JS Lott
Protein expression and purification 57 (1), 81-87, 2008
The potential impact of structural genomics on tuberculosis drug discovery
VL Arcus, JS Lott, JM Johnston, EN Baker
Drug discovery today 11 (1-2), 28-34, 2006
Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI)
A Manos‐Turvey, EMM Bulloch, PJ Rutledge, EN Baker, JS Lott, ...
ChemMedChem 5 (7), 1067-1079, 2010
The TB Structural Genomics Consortium: a decade of progress
N Chim, JE Habel, JM Johnston, I Krieger, L Miallau, ...
Tuberculosis 91 (2), 155-172, 2011
A single WW domain is the predominant mediator of the interaction between the human ubiquitin-protein ligase Nedd4 and the human epithelial sodium channel
JS Lott, SJ Coddington-Lawson, PH Teesdale-Spittle, FJ McDonald
Biochemical Journal 361 (3), 481-488, 2002
The crystal structure of TrpD, a metabolic enzyme essential for lung colonization by Mycobacterium tuberculosis, in complex with its substrate phosphoribosylpyrophosphate
CE Lee, C Goodfellow, F Javid-Majd, EN Baker, JS Lott
Journal of molecular biology 355 (4), 784-797, 2006
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