| Functional heteromerization of HCN1 and HCN2 pacemaker channels C Ulens, J Tytgat Journal of Biological Chemistry 276 (9), 6069-6072, 2001 | 289 | 2001 |
| Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP C Ulens, RC Hogg, PH Celie, D Bertrand, V Tsetlin, AB Smit, TK Sixma Proceedings of the National Academy of Sciences 103 (10), 3615-3620, 2006 | 257 | 2006 |
| AChBP‐targeted α‐conotoxin correlates distinct binding orientations with nAChR subtype selectivity S Dutertre, C Ulens, R Büttner, A Fish, R van Elk, Y Kendel, G Hopping, ... The EMBO journal 26 (16), 3858-3867, 2007 | 198 | 2007 |
| Structural insights into Cys-loop receptor function and ligand recognition M Nys, D Kesters, C Ulens Biochemical pharmacology 86 (8), 1042-1053, 2013 | 160 | 2013 |
| Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines R Spurny, J Ramerstorfer, K Price, M Brams, M Ernst, H Nury, M Verheij, ... Proceedings of the National Academy of Sciences 109 (44), E3028-E3034, 2012 | 149 | 2012 |
| Regulation of hyperpolarization-activated HCN channels by cAMP through a gating switch in binding domain symmetry C Ulens, SA Siegelbaum Neuron 40 (5), 959-970, 2003 | 136 | 2003 |
| Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptor R Spurny, S Debaveye, A Farinha, K Veys, AM Vos, T Gossas, J Atack, ... Proceedings of the National Academy of Sciences 112 (19), E2543-E2552, 2015 | 119 | 2015 |
| A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors M Brams, A Pandya, D Kuzmin, R Van Elk, L Krijnen, JL Yakel, V Tsetlin, ... PLoS biology 9 (3), e1001034, 2011 | 118 | 2011 |
| Use of acetylcholine binding protein in the search for novel α7 nicotinic receptor ligands. In silico docking, pharmacological screening, and X-ray analysis C Ulens, A Akdemir, A Jongejan, R Van Elk, S Bertrand, A Perrakis, ... Journal of medicinal chemistry 52 (8), 2372-2383, 2009 | 112 | 2009 |
| Structure of NPP1, an ectonucleotide pyrophosphatase/phosphodiesterase involved in tissue calcification S Jansen, A Perrakis, C Ulens, C Winkler, M Andries, RP Joosten, ... Structure 20 (11), 1948-1959, 2012 | 100 | 2012 |
| Multisite binding of a general anesthetic to the prokaryotic pentameric Erwinia chrysanthemi ligand-gated ion channel (ELIC) R Spurny, B Billen, RJ Howard, M Brams, S Debaveye, KL Price, ... Journal of Biological Chemistry 288 (12), 8355-8364, 2013 | 97 | 2013 |
| A novel conotoxin from Conus betulinus, κ-BtX, unique in cysteine pattern and in function as a specific BK channel modulator CX Fan, XK Chen, C Zhang, LX Wang, KL Duan, LL He, Y Cao, SY Liu, ... Journal of Biological Chemistry 278 (15), 12624-12633, 2003 | 96 | 2003 |
| Structural basis of ligand recognition in 5‐HT3 receptors D Kesters, AJ Thompson, M Brams, R Van Elk, R Spurny, M Geitmann, ... EMBO reports 14 (1), 49-56, 2013 | 92 | 2013 |
| Molecular actions of smoking cessation drugs at α4β2 nicotinic receptors defined in crystal structures of a homologous binding protein B Billen, R Spurny, M Brams, R van Elk, S Valera-Kummer, JL Yakel, ... Proceedings of the National Academy of Sciences 109 (23), 9173-9178, 2012 | 88 | 2012 |
| Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels T Olamendi-Portugal, BI García, I López-González, J Van Der Walt, ... Biochemical and biophysical research communications 299 (4), 562-568, 2002 | 84 | 2002 |
| Structural hot spots for the solubility of globular proteins A Ganesan, A Siekierska, J Beerten, M Brams, J Van Durme, G De Baets, ... Nature communications 7 (1), 10816, 2016 | 62 | 2016 |
| Crystal structures of a cysteine-modified mutant in loop D of acetylcholine-binding protein M Brams, EA Gay, JC Sáez, A Guskov, R van Elk, RC van der Schors, ... Journal of biological chemistry 286 (6), 4420-4428, 2011 | 60 | 2011 |
| Family of prokaryote cyclic nucleotide-modulated ion channels M Brams, J Kusch, R Spurny, K Benndorf, C Ulens Proceedings of the National Academy of Sciences 111 (21), 7855-7860, 2014 | 59 | 2014 |
| Morphine-6β-glucuronide and morphine-3-glucuronide, opioid receptor agonists with different potencies C Ulens, L Baker, A Ratka, D Waumans, J Tytgat Biochemical pharmacology 62 (9), 1273-1282, 2001 | 54 | 2001 |
| A lipid site shapes the agonist response of a pentameric ligand-gated ion channel CM Hénault, C Govaerts, R Spurny, M Brams, A Estrada-Mondragon, ... Nature chemical biology 15 (12), 1156-1164, 2019 | 49 | 2019 |
