| Bias factor and therapeutic window correlate to predict safer opioid analgesics CL Schmid, NM Kennedy, NC Ross, KM Lovell, Z Yue, J Morgenweck, ... Cell 171 (5), 1165-1175. e13, 2017 | 475 | 2017 |
| Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria Y O'Malley, BD Fink, NC Ross, TE Prisinzano, WI Sivitz Journal of biological chemistry 281 (52), 39766-39775, 2006 | 144 | 2006 |
| Novel opioid cyclic tetrapeptides: Trp isomers of CJ‐15,208 exhibit distinct opioid receptor agonism and short‐acting κ opioid receptor antagonism NC Ross, KJ Reilley, TF Murray, JV Aldrich, JP McLaughlin British Journal of Pharmacology 165 (4b), 1097-1108, 2012 | 56 | 2012 |
| Optimization of a series of mu opioid receptor (MOR) agonists with high G protein signaling bias NM Kennedy, CL Schmid, NC Ross, KM Lovell, Z Yue, YT Chen, ... Journal of medicinal chemistry 61 (19), 8895-8907, 2018 | 55 | 2018 |
| Physical presence of nor-binaltorphimine in mouse brain over 21 days after a single administration corresponds to its long-lasting antagonistic effect on κ-opioid receptors KA Patkar, J Wu, ML Ganno, HD Singh, NC Ross, K Rasakham, L Toll, ... Journal of Pharmacology and Experimental Therapeutics 346 (3), 545-554, 2013 | 49 | 2013 |
| The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior JV Aldrich, SN Senadheera, NC Ross, ML Ganno, SO Eans, ... Journal of natural products 76 (3), 433-438, 2013 | 43 | 2013 |
| Unexpected Opioid Activity Profiles of Analogues of the Novel Peptide Kappa Opioid Receptor Ligand CJ‐15,208 JV Aldrich, SS Kulkarni, SN Senadheera, NC Ross, KJ Reilley, SO Eans, ... ChemMedChem 6 (9), 1739-1745, 2011 | 41 | 2011 |
| Mitochondrial targeted coenzyme Q, superoxide, and fuel selectivity in endothelial cells BD Fink, Y O'Malley, BL Dake, NC Ross, TE Prisinzano, WI Sivitz PLoS One 4 (1), e4250, 2009 | 38 | 2009 |
| Reactions of some cyclopentenones with selected cysteine derivatives and biological activities of the product thioethers JF Bickley, A Ciucci, P Evans, SM Roberts, N Ross, MG Santoro Bioorganic & medicinal chemistry 12 (12), 3221-3227, 2004 | 37 | 2004 |
| Synthesis of CJ-15,208, a novel κ-opioid receptor antagonist NC Ross, SS Kulkarni, JP McLaughlin, JV Aldrich Tetrahedron letters 51 (38), 5020-5023, 2010 | 31 | 2010 |
| Alanine analogues of [D‐T rp] CJ‐15,208: novel opioid activity profiles and prevention of drug‐and stress‐induced reinstatement of cocaine‐seeking behaviour JV Aldrich, SN Senadheera, NC Ross, KA Reilley, ML Ganno, SE Eans, ... British Journal of Pharmacology 171 (13), 3212-3222, 2014 | 26 | 2014 |
| Synthesis of cyclic tetrapeptide CJ 15,208: a novel kappa opioid receptor antagonist SS Kulkarni, NC Ross, JP McLaughlin, JV Aldrich Peptides for Youth: The Proceedings of the 20th American Peptide Symposium …, 2009 | 12 | 2009 |
| Cyclic tetrapeptides JV Aldrich, NC Ross, S Kulkarni US Patent 8,809,278, 2014 | 7 | 2014 |
| Pharmaceutical compositions SM Roberts, MG Santoro, V Jadhav, AM Happe, P Evans, NC Ross, ... US Patent 7,759,399, 2010 | 1 | 2010 |
| Substitution of Aromatic Residues in the Macrocyclic Opioid Peptide [D-Trp] CJ-15,208 Alters the Opioid Activity Profile in vivo J Aldrich, D Yakovlev, N Ross, S Eans, H Stacy, T Murray, J McLaughlin JOURNAL OF PEPTIDE SCIENCE 24, S69-S69, 2018 | | 2018 |
| Mu Opioid Receptor Agonists with Dopamine D3 Receptor Antagonism: Toward Developing Analgesics with Less Abuse Potential NM Shah, CL Schmid, B Merritt, NM Kennedy, NC Ross, KM Lovell, ... The FASEB Journal 32, 689.1-689.1, 2018 | | 2018 |
| Novel kappa opioid peptides with drug-like properties JV Aldrich, SS Kulkarni, SN Senadheera, NC Ross, KJ Reilley, SO Eans, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | | 2011 |
| Orally Active Opioid Peptides as Leads for Drug Development JV Aldrich, SS Kulkarni, SN Senadheera, NC Ross, KJ Reilley, SO Eans, ... BIOPOLYMERS 96 (4), 465-466, 2011 | | 2011 |
| Synthesis of cyclic tetrapeptide CJ 15, 208: A novel kappa opioid receptor antagonist SS Kulkami, NC Ross, JP McLaughlin, TF Murray, JV Aldrich BIOPOLYMERS 88 (4), 621-621, 2007 | | 2007 |
| The latest version is at Y O'Malley, BD Fink, NC Ross, TE Prisinzano, WI Sivitz | | 2006 |
