Connie Eaves
Connie Eaves
Terry Fox Laboratory, BC Cancer Agency
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Cancer stem cells—perspectives on current status and future directions: AACR Workshop on cancer stem cells
MF Clarke, JE Dick, PB Dirks, CJ Eaves, CHM Jamieson, DL Jones, ...
Cancer research 66 (19), 9339-9344, 2006
The clonal and mutational evolution spectrum of primary triple-negative breast cancers
SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ...
Nature 486 (7403), 395-399, 2012
Purification and unique properties of mammary epithelial stem cells
J Stingl, P Eirew, I Ricketson, M Shackleton, F Vaillant, D Choi, HI Li, ...
Nature 439 (7079), 993-997, 2006
Cancer stem cells: an evolving concept
LV Nguyen, R Vanner, P Dirks, CJ Eaves
Nature Reviews Cancer 12 (2), 133-143, 2012
Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells
RD Morin, MD O’Connor, M Griffith, F Kuchenbauer, A Delaney, ...
Genome research 18 (4), 610-621, 2008
Characterization and partial purification of human marrow cells capable of initiating long-term hematopoiesis in vitro
HJ Sutherland, CJ Eaves, AC Eaves, W Dragowska, PM Lansdorp
Functional characterization of individual human hematopoietic stem cells cultured at limiting dilution on supportive marrow stromal layers.
HJ Sutherland, PM Lansdorp, DH Henkelman, AC Eaves, CJ Eaves
Proceedings of the National Academy of Sciences 87 (9), 3584-3588, 1990
Cancer stem cell definitions and terminology: the devil is in the details
P Valent, D Bonnet, R De Maria, T Lapidot, M Copland, JV Melo, ...
Nature Reviews Cancer 12 (11), 767-775, 2012
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo.
G Sauvageau, U Thorsteinsdottir, CJ Eaves, HJ Lawrence, C Largman, ...
Genes & development 9 (14), 1753-1765, 1995
Long-term propagation of distinct hematopoietic differentiation programs in vivo
B Dykstra, D Kent, M Bowie, L McCaffrey, M Hamilton, K Lyons, SJ Lee, ...
Cell stem cell 1 (2), 218-229, 2007
Correction of sickle cell disease in transgenic mouse models by gene therapy
R Pawliuk, KA Westerman, ME Fabry, E Payen, R Tighe, EE Bouhassira, ...
Science 294 (5550), 2368-2371, 2001
Demonstration of permanent factor-dependent multipotential (erythroid/neutrophil/basophil) hematopoietic progenitor cell lines.
JS Greenberger, MA Sakakeeny, RK Humphries, CJ Eaves, RJ Eckner
Proceedings of the National Academy of Sciences 80 (10), 2931-2935, 1983
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia
M Škrtić, S Sriskanthadevan, B Jhas, M Gebbia, X Wang, Z Wang, ...
Cancer cell 20 (5), 674-688, 2011
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells.
G Sauvageau, PM Lansdorp, CJ Eaves, DE Hogge, WH Dragowska, ...
Proceedings of the National Academy of Sciences 91 (25), 12223-12227, 1994
Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia
T Holyoake, X Jiang, C Eaves, A Eaves
Blood, The Journal of the American Society of Hematology 94 (6), 2056-2064, 1999
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution
P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ...
Nature 518 (7539), 422-426, 2015
Hematopoietic stem cells: concepts, definitions, and the new reality
CJ Eaves
Blood, The Journal of the American Society of Hematology 125 (17), 2605-2613, 2015
Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal
I Fares, J Chagraoui, Y Gareau, S Gingras, R Ruel, N Mayotte, E Csaszar, ...
Science 345 (6203), 1509-1512, 2014
Quantitative assay for totipotent reconstituting hematopoietic stem cells by a competitive repopulation strategy.
SJ Szilvassy, RK Humphries, PM Lansdorp, AC Eaves, CJ Eaves
Proceedings of the National Academy of Sciences 87 (22), 8736-8740, 1990
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
KG Leong, K Niessen, I Kulic, A Raouf, C Eaves, I Pollet, A Karsan
The Journal of experimental medicine 204 (12), 2935-2948, 2007
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