| Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung AA Pezzulo, XX Tang, MJ Hoegger, MHA Alaiwa, S Ramachandran, ... Nature 487 (7405), 109, 2012 | 942 | 2012 |
| Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ... Science 321 (5897), 1837-1841, 2008 | 878 | 2008 |
| Origins of cystic fibrosis lung disease DA Stoltz, DK Meyerholz, MJ Welsh New England Journal of Medicine 372 (4), 351-362, 2015 | 629 | 2015 |
| Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ... Science translational medicine 2 (29), 29ra31-29ra31, 2010 | 569 | 2010 |
| Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transfer CS Rogers, Y Hao, T Rokhlina, M Samuel, DA Stoltz, Y Li, E Petroff, ... The Journal of clinical investigation 118 (4), 1571-1577, 2008 | 505 | 2008 |
| Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis MJ Hoegger, AJ Fischer, JD McMenimen, LS Ostedgaard, AJ Tucker, ... Science 345 (6198), 818-822, 2014 | 404 | 2014 |
| IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines P Schwarzenberger, V La Russa, A Miller, P Ye, W Huang, A Zieske, ... The Journal of Immunology 161 (11), 6383-6389, 1998 | 396 | 1998 |
| Restoring cystic fibrosis transmembrane conductance regulator function reduces airway bacteria and inflammation in people with cystic fibrosis and chronic lung infections KB Hisert, SL Heltshe, C Pope, P Jorth, X Wu, RM Edwards, M Radey, ... American journal of respiratory and critical care medicine 195 (12), 1617-1628, 2017 | 323 | 2017 |
| Airway acidification initiates host defense abnormalities in cystic fibrosis mice VS Shah, DK Meyerholz, XX Tang, L Reznikov, MA Alaiwa, SE Ernst, ... Science 351 (6272), 503-507, 2016 | 323 | 2016 |
| The porcine lung as a potential model for cystic fibrosis CS Rogers, WM Abraham, KA Brogden, JF Engelhardt, JT Fisher, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (2 …, 2008 | 296 | 2008 |
| Acidic pH increases airway surface liquid viscosity in cystic fibrosis XX Tang, LS Ostedgaard, MJ Hoegger, TO Moninger, PH Karp, ... The Journal of clinical investigation 126 (3), 879-891, 2016 | 276 | 2016 |
| Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia JH Chen, DA Stoltz, PH Karp, SE Ernst, AA Pezzulo, TO Moninger, ... Cell 143 (6), 911-923, 2010 | 266 | 2010 |
| The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis–like disease in pigs LS Ostedgaard, DK Meyerholz, JH Chen, AA Pezzulo, PH Karp, ... Science translational medicine 3 (74), 74ra24-74ra24, 2011 | 234 | 2011 |
| pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37 MHA Alaiwa, LR Reznikov, ND Gansemer, KA Sheets, AR Horswill, ... Proceedings of the National Academy of Sciences 111 (52), 18703-18708, 2014 | 223 | 2014 |
| Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment MP Rogan, DA Stoltz, DB Hornick Chest 139 (6), 1480-1490, 2011 | 206 | 2011 |
| Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children DK Meyerholz, DA Stoltz, E Namati, S Ramachandran, AA Pezzulo, ... American journal of respiratory and critical care medicine 182 (10), 1251-1261, 2010 | 202 | 2010 |
| Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis RD Gray, G Hardisty, KH Regan, M Smith, CT Robb, R Duffin, A Mackellar, ... Thorax 73 (2), 134-144, 2018 | 188 | 2018 |
| Pathology of gastrointestinal organs in a porcine model of cystic fibrosis DK Meyerholz, DA Stoltz, AA Pezzulo, MJ Welsh The American journal of pathology 176 (3), 1377-1389, 2010 | 177 | 2010 |
| Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia DA Stoltz, EA Ozer, CJ Ng, JM Yu, ST Reddy, AJ Lusis, N Bourquard, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 292 (4 …, 2007 | 171 | 2007 |
| Gel-forming mucins form distinct morphologic structures in airways LS Ostedgaard, TO Moninger, JD McMenimen, NM Sawin, CP Parker, ... Proceedings of the National Academy of Sciences 114 (26), 6842-6847, 2017 | 156 | 2017 |
