Philip J. Moos
Philip J. Moos
Associate Professor of Pharmacology & Toxicology
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ZnO particulate matter requires cell contact for toxicity in human colon cancer cells
PJ Moos, K Chung, D Woessner, M Honeggar, NS Cutler, JM Veranth
Chemical research in toxicology 23 (4), 733-739, 2010
Electrophilic prostaglandins and lipid aldehydes repress redox-sensitive transcription factors p53 and hypoxia-inducible factor by impairing the selenoprotein thioredoxin reductase
PJ Moos, K Edes, P Cassidy, E Massuda, FA Fitzpatrick
Journal of Biological Chemistry 278 (2), 745-750, 2003
Taxane-mediated gene induction is independent of microtubule stabilization: induction of transcription regulators and enzymes that modulate inflammation and apoptosis
PJ Moos, FA Fitzpatrick
Proceedings of the National Academy of Sciences 95 (7), 3896-3901, 1998
Curcumin impairs tumor suppressor p53 function in colon cancer cells
PJ Moos, K Edes, JE Mullally, FA Fitzpatrick
Carcinogenesis 25 (9), 1611-1617, 2004
Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway
JE Mullally, PJ Moos, K Edes, FA Fitzpatrick
Journal of Biological Chemistry 276 (32), 30366-30373, 2001
Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles
PB Cassidy, K Edes, CC Nelson, K Parsawar, FA Fitzpatrick, PJ Moos
Carcinogenesis 27 (12), 2538-2549, 2006
Identification of gene expression profiles that segregate patients with childhood leukemia
PJ Moos, EA Raetz, MA Carlson, A Szabo, FE Smith, C Willman, Q Wei, ...
Clinical Cancer Research 8 (10), 3118-3130, 2002
Combating subclonal evolution of resistant cancer phenotypes
SW Brady, JA McQuerry, Y Qiao, SR Piccolo, G Shrestha, DF Jenkins, ...
Nature communications 8 (1), 1-15, 2017
Responses of human cells to ZnO nanoparticles: a gene transcription study
PJ Moos, K Olszewski, M Honeggar, P Cassidy, S Leachman, ...
Metallomics 3 (11), 1199-1211, 2011
Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells
KC Thomas, AS Sabnis, ME Johansen, DL Lanza, PJ Moos, GS Yost, ...
Journal of Pharmacology and Experimental Therapeutics 321 (3), 830-838, 2007
Taxanes propagate apoptosis via two cell populations with distinctive cytological and molecular traits
PJ Moos, FA Fitzpatrick
Cell Growth and Differentiation-Publication American Association for Cancer …, 1998
Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins
PJ Moos, K Edes, FA Fitzpatrick
Proceedings of the National Academy of Sciences 97 (16), 9215-9220, 2000
Thioredoxin reductase 1 knockdown enhances selenazolidine cytotoxicity in human lung cancer cells via mitochondrial dysfunction
RL Poerschke, PJ Moos
Biochemical pharmacology 81 (2), 211-221, 2011
Differential gene expression in primary human skin keratinocytes and fibroblasts in response to ionizing radiation
RL Warters, AT Packard, GF Kramer, DK Gaffney, PJ Moos
Radiation research 172 (1), 82-95, 2009
Effect of taxol and taxotere on gene expression in macrophages: induction of the prostaglandin H synthase-2 isoenzyme
PJ Moos, DT Muskardin, FA Fitzpatrick
The Journal of Immunology 162 (1), 467-473, 1999
Diversity of the apoptotic response to chemotherapy in childhood leukemia
T Liu, E Raetz, PJ Moos, SL Perkins, CS Bruggers, F Smith, WL Carroll
Leukemia 16 (2), 223-232, 2002
Genotoxicity of amorphous silica nanoparticles: Status and prospects
M Yazdimamaghani, PJ Moos, MA Dobrovolskaia, H Ghandehari
Nanomedicine: Nanotechnology, Biology and Medicine 16, 106-125, 2019
Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes
KY Margaret, PJ Moos, P Cassidy, M Wade, FA Fitzpatrick
Journal of Biological Chemistry 279 (27), 28028-28035, 2004
Selenium for the prevention of cutaneous melanoma
PB Cassidy, HD Fain, JP Cassidy Jr, SM Tran, PJ Moos, KM Boucher, ...
Nutrients 5 (3), 725-749, 2013
Identification of genes that are regulated transcriptionally by Myc in childhood tumors
EA Raetz, MKH Kim, P Moos, M Carlson, C Bruggers, DK Hooper, L Foot, ...
Cancer: Interdisciplinary International Journal of the American Cancer …, 2003
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