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Karim Rafie
Karim Rafie
Assistant Professor, Groningen University
Verified email at rug.nl
Title
Cited by
Cited by
Year
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity
KC Pao, NT Wood, A Knebel, K Rafie, M Stanley, PD Mabbitt, ...
Nature 556 (7701), 381-385, 2018
2062018
The active site of O-GlcNAc transferase imposes constraints on substrate sequence
S Pathak, J Alonso, M Schimpl, K Rafie, DE Blair, VS Borodkin, ...
Nature structural & molecular biology 22 (9), 744-750, 2015
1382015
O-GlcNAc transferase inhibitors: current tools and future challenges
R Trapannone, K Rafie, DMF Van Aalten
Biochemical Society Transactions 44 (1), 88-93, 2016
1002016
Bisubstrate UDP–peptide conjugates as human O-GlcNAc transferase inhibitors
VS Borodkin, M Schimpl, M Gundogdu, K Rafie, HC Dorfmueller, ...
Biochemical Journal 457 (3), 497-502, 2014
762014
Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46
BD Persson, L John, K Rafie, M Strebl, L Frängsmyr, MZ Ballmann, ...
Proceedings of the National Academy of Sciences 118 (3), e2020732118, 2021
582021
Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats
K Rafie, O Raimi, AT Ferenbach, VS Borodkin, V Kapuria, DMF van Aalten
Open biology 7 (6), 170078, 2017
582017
The structure of enteric human adenovirus 41—A leading cause of diarrhea in children
K Rafie, A Lenman, J Fuchs, A Rajan, N Arnberg, LA Carlson
Science advances 7 (2), eabe0974, 2021
512021
Thio-linked UDP–peptide conjugates as O-GlcNAc transferase inhibitors
K Rafie, A Gorelik, R Trapannone, VS Borodkin, DMF van Aalten
Bioconjugate chemistry 29 (6), 1834-1840, 2018
412018
Direct monitoring of protein O-GlcNAcylation by high-resolution native mass spectrometry
AC Leney, K Rafie, DMF Van Aalten, AJR Heck
ACS chemical biology 12 (8), 2078-2084, 2017
282017
UDP‐GlcNAc Analogues as Inhibitors of O‐GlcNAc Transferase (OGT): Spectroscopic, Computational, and Biological Studies
M Ghirardello, D Perrone, N Chinaglia, D Sádaba, I Delso, T Tejero, ...
Chemistry–A European Journal 24 (28), 7264-7272, 2018
162018
O-GlcNAcase fragment discovery with fluorescence polarimetry
VS Borodkin, K Rafie, N Selvan, T Aristotelous, I Navratilova, ...
ACS chemical biology 13 (5), 1353-1360, 2018
102018
Clinically observed deletions in SARS‐CoV‐2 Nsp1 affect its stability and ability to inhibit translation
P Kumar, E Schexnaydre, K Rafie, T Kurata, I Terenin, V Hauryliuk, ...
Febs Letters 596 (9), 1203-1213, 2022
42022
Author Correction: The active site of O-GlcNAc transferase imposes constraints on substrate sequence
S Pathak, J Alonso, M Schimpl, K Rafie, DE Blair, VS Borodkin, ...
Nature structural & molecular biology 30 (4), 564, 2023
2023
Giardia intestinalis deoxyadenosine kinase has a unique tetrameric structure that enables high substrate affinity and makes the parasite sensitive to deoxyadenosine analogues
F Ranjbarian, K Rafie, K Shankar, S Krakovka, SG Svärd, LA Carlson, ...
bioRxiv, 2023.12. 18.572228, 2023
2023
Kinetics of the adenosine triphosphatase and helicase activity of the chikungunya virus polyprotein and nsP2
T Laurent, L Nenzén, K Rafie, LA Carlson
2023
Clinically observed deletions in SARS-CoV-2 Nsp1 affect protein stability and its ability to inhibit translation
P Kumar, E Schexnaydre, K Rafie, I Terenin, V Hauryliuk, LA Carlson
bioRxiv, 2021.11. 03.467065, 2021
2021
Clinically observed deletions in SARS-CoV-2 Nsp1 affect protein stability and its ability to inhibit translation (preprint)
P Kumar, E Schexnaydre, K Rafie, I Terenin, V Hauryliuk, LA Carlson
2021
Developing O-GlcNAc Transferase Inhibitors: Insights from Substrate Recognition
K Rafie
University of Dundee, 2017
2017
Goblins: Bisubstrate inhibitors targeting the O-GlcNAc transferase
K Rafie, V Borodkin, R Trapannone, DMF Van Aalten
University of Dundee. College of Life Sciences 2015 Research Symposium, 2015
2015
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