| New 1, 3, 4-thiadiazole derivatives endowed with analgesic and anti-inflammatory activities S Schenone, C Brullo, O Bruno, F Bondavalli, A Ranise, W Filippelli, ... Bioorganic & medicinal chemistry 14 (6), 1698-1705, 2006 | 313 | 2006 |
| GEBR‐7b, a novel PDE4D selective inhibitor that improves memory in rodents at non‐emetic doses O Bruno, E Fedele, J Prickaerts, LA Parker, E Canepa, C Brullo, ... British journal of pharmacology 164 (8), 2054-2063, 2011 | 144 | 2011 |
| Improvement of spatial memory function in APPswe/PS1dE9 mice after chronic inhibition of phosphodiesterase type 4D ASR Sierksma, DLA Van Den Hove, F Pfau, M Philippens, O Bruno, ... Neuropharmacology 77, 120-130, 2014 | 132 | 2014 |
| Synthesis, antiplatelet and antithrombotic activities of new 2-substituted benzopyrano [4, 3-d] pyrimidin-4-cycloamines and 4-amino/cycloamino-benzopyrano [4, 3-d] pyrimidin-5-ones O Bruno, C Brullo, S Schenone, F Bondavalli, A Ranise, M Tognolini, ... Bioorganic & medicinal chemistry 14 (1), 121-130, 2006 | 118 | 2006 |
| 3-Arylsulphonyl-5-arylamino-1, 3, 4-thiadiazol-2 (3H) ones as anti-inflammatory and analgesic agents S Schenone, O Bruno, A Ranise, F Bondavalli, W Filippelli, G Falcone, ... Bioorganic & medicinal chemistry 9 (8), 2149-2153, 2001 | 116 | 2001 |
| New pyrazolo [3, 4-d] pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation S Schenone, O Bruno, A Ranise, F Bondavalli, C Brullo, P Fossa, L Mosti, ... Bioorganic & medicinal chemistry letters 14 (10), 2511-2517, 2004 | 112 | 2004 |
| Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ... Journal of medicinal chemistry 49 (5), 1549-1561, 2006 | 111 | 2006 |
| Progress in 5H [1] benzopyrano [4, 3-d] pyrimidin-5-amine series: 2-methoxy derivatives effective as antiplatelet agents with analgesic activity O Bruno, C Brullo, S Schenone, A Ranise, F Bondavalli, E Barocelli, ... Il Farmaco 57 (9), 753-758, 2002 | 108 | 2002 |
| Identification of a Novel Pyrazolo[3,4-d]pyrimidine Able To Inhibit Cell Proliferation of a Human Osteogenic Sarcoma in Vitro and in a Xenograft Model in Mice F Manetti, A Santucci, GA Locatelli, G Maga, A Spreafico, T Serchi, ... Journal of medicinal chemistry 50 (23), 5579-5588, 2007 | 103 | 2007 |
| Structure-Based Optimization of Pyrazolo[3,4-d]pyrimidines as Abl Inhibitors and Antiproliferative Agents toward Human Leukemia Cell Lines F Manetti, C Brullo, M Magnani, F Mosci, B Chelli, E Crespan, ... Journal of medicinal chemistry 51 (5), 1252-1259, 2008 | 96 | 2008 |
| Synthesis and pharmacological evaluation of 2, 5-cycloamino-5H-[1] benzopyrano [4, 3-d] pyrimidines endowed with in vitro antiplatelet activity O Bruno, C Brullo, A Ranise, S Schenone, F Bondavalli, E Barocelli, ... Bioorganic & medicinal chemistry letters 11 (11), 1397-1400, 2001 | 93 | 2001 |
| Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo [3, 4-d] pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line S Schenone, O Bruno, F Bondavalli, A Ranise, L Mosti, G Menozzi, ... European journal of medicinal chemistry 39 (11), 939-946, 2004 | 92 | 2004 |
| Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo [3, 4-d] pyrimidines S Schenone, C Brullo, O Bruno, F Bondavalli, L Mosti, G Maga, E Crespan, ... European journal of medicinal chemistry 43 (12), 2665-2676, 2008 | 89 | 2008 |
| Antiinflammatory agents: new series of N-substituted amino acids with complex pyrimidine structures endowed with antiphlogistic activity O Bruno, S Schenone, A Ranise, F Bondavalli, W Filippelli, G Falcone, ... Il Farmaco 54 (1-2), 95-100, 1999 | 82 | 1999 |
| Synthesis and 3D QSAR of new pyrazolo [3, 4-b] pyridines: potent and selective inhibitors of A1 adenosine receptors F Manetti, S Schenone, F Bondavalli, C Brullo, O Bruno, A Ranise, L Mosti, ... Journal of medicinal chemistry 48 (23), 7172-7185, 2005 | 76 | 2005 |
| New polycyclic pyrimidine derivatives with antiplatelet in vitro activity: synthesis and pharmacological screening O Bruno, S Schenone, A Ranise, F Bondavalli, E Barocelli, V Ballabeni, ... Bioorganic & medicinal chemistry 9 (3), 629-636, 2001 | 71 | 2001 |
| Structure-based design, parallel synthesis, structure− activity relationship, and molecular modeling studies of thiocarbamates, new potent non-nucleoside HIV-1 reverse … A Ranise, A Spallarossa, S Cesarini, F Bondavalli, S Schenone, O Bruno, ... Journal of medicinal chemistry 48 (11), 3858-3873, 2005 | 67 | 2005 |
| Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer’s disease R Ricciarelli, C Brullo, J Prickaerts, O Arancio, C Villa, C Rebosio, ... Scientific Reports 7 (1), 46320, 2017 | 66 | 2017 |
| Synthesis and pharmacological evaluation of 5H-[1] benzopyrano [4, 3-d] pyrimidines effective as antiplatelet/analgesic agents O Bruno, C Brullo, S Schenone, F Bondavalli, A Ranise, M Tognolini, ... Bioorganic & medicinal chemistry 12 (3), 553-561, 2004 | 66 | 2004 |
| Synthesis, molecular modeling studies, and pharmacological activity of selective A1 receptor antagonists F Bondavalli, M Botta, O Bruno, A Ciacci, F Corelli, P Fossa, A Lucacchini, ... Journal of medicinal chemistry 45 (22), 4875-4887, 2002 | 66 | 2002 |
