| Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature PG Arnison, MJ Bibb, G Bierbaum, AA Bowers, TS Bugni, G Bulaj, ... Natural product reports 30 (1), 108-160, 2013 | 2008 | 2013 |
| A genomics-guided approach for discovering and expressing cryptic metabolic pathways E Zazopoulos, K Huang, A Staffa, W Liu, BO Bachmann, K Nonaka, ... Nature biotechnology 21 (2), 187-190, 2003 | 404 | 2003 |
| Biosynthesis of the enediyne antitumor antibiotic C-1027 W Liu, SD Christenson, S Standage, B Shen Science 297 (5584), 1170-1173, 2002 | 349 | 2002 |
| Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications R Liao, L Duan, C Lei, H Pan, Y Ding, Q Zhang, D Chen, B Shen, Y Yu, ... Chemistry & biology 16 (2), 141-147, 2009 | 230 | 2009 |
| Radical-mediated enzymatic methylation: a tale of two SAMS QI Zhang, WA Van Der Donk, W Liu Accounts of Chemical Research 45 (4), 555-564, 2012 | 229 | 2012 |
| Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis XY Jia, ZH Tian, L Shao, XD Qu, QF Zhao, J Tang, GL Tang, W Liu Chemistry & biology 13 (6), 575-585, 2006 | 194 | 2006 |
| Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework Y Yu, L Duan, Q Zhang, R Liao, Y Ding, H Pan, E Wendt-Pienkowski, ... ACS chemical biology 4 (10), 855-864, 2009 | 189 | 2009 |
| Characterization of the Maduropeptin Biosynthetic Gene Cluster from Actinomadura madurae ATCC 39144 Supporting a Unifying Paradigm for Enediyne … SG Van Lanen, T Oh, W Liu, E Wendt-Pienkowski, B Shen Journal of the American Chemical Society 129 (43), 13082-13094, 2007 | 157 | 2007 |
| A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis SD Christenson, W Liu, MD Toney, B Shen Journal of the American Chemical Society 125 (20), 6062-6063, 2003 | 147 | 2003 |
| The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases W Liu, K Nonaka, L Nie, J Zhang, SD Christenson, J Bae, SG Van Lanen, ... Chemistry & biology 12 (3), 293-302, 2005 | 145 | 2005 |
| An enzymatic [4+ 2] cyclization cascade creates the pentacyclic core of pyrroindomycins Z Tian, P Sun, Y Yan, Z Wu, Q Zheng, S Zhou, H Zhang, F Yu, X Jia, ... Nature chemical biology 11 (4), 259-265, 2015 | 142 | 2015 |
| Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A Q Zhao, M Wang, D Xu, Q Zhang, W Liu Nature 518 (7537), 115-119, 2015 | 139 | 2015 |
| Characterization of the Saframycin A Gene Cluster from Streptomyces lavendulae NRRL 11002 Revealing a Nonribosomal Peptide Synthetase System for … L Li, W Deng, J Song, W Ding, QF Zhao, C Peng, WW Song, GL Tang, ... Journal of bacteriology 190 (1), 251-263, 2008 | 135 | 2008 |
| Radical-mediated enzymatic carbon chain fragmentation-recombination Q Zhang, Y Li, D Chen, Y Yu, L Duan, B Shen, W Liu Nature chemical biology 7 (3), 154-160, 2011 | 134 | 2011 |
| Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis Q Zhao, Q He, W Ding, M Tang, Q Kang, Y Yu, W Deng, Q Zhang, J Fang, ... Chemistry & biology 15 (7), 693-705, 2008 | 125 | 2008 |
| Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model W Liu, J Ahlert, Q Gao, E Wendt-Pienkowski, B Shen, JS Thorson Proceedings of the National Academy of Sciences 100 (21), 11959-11963, 2003 | 116 | 2003 |
| Genes for Production of the Enediyne Antitumor Antibiotic C-1027 in Streptomyces globisporus Are Clustered with the cagA Gene That Encodes the C-1027 … W Liu, B Shen Antimicrobial agents and chemotherapy 44 (2), 382-392, 2000 | 110 | 2000 |
| A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis J Zhang, SG Van Lanen, J Ju, W Liu, PC Dorrestein, W Li, NL Kelleher, ... Proceedings of the National Academy of Sciences 105 (5), 1460-1465, 2008 | 109 | 2008 |
| Cloning and Characterization of the Tetrocarcin A Gene Cluster from Micromonospora chalcea NRRL 11289 Reveals a Highly Conserved Strategy for Tetronate … J Fang, Y Zhang, L Huang, X Jia, Q Zhang, X Zhang, G Tang, W Liu Journal of bacteriology 190 (17), 6014-6025, 2008 | 106 | 2008 |
| Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea … Y Chen, W Deng, J Wu, J Qian, J Chu, Y Zhuang, S Zhang, W Liu Applied and Environmental Microbiology 74 (6), 1820-1828, 2008 | 104 | 2008 |
