Evidence for intramyocardial disruption of lipid metabolism and increased myocardial ketone utilization in advanced human heart failure KC Bedi Jr, NW Snyder, J Brandimarto, M Aziz, C Mesaros, AJ Worth, ... Circulation 133 (8), 706-716, 2016 | 530 | 2016 |
Targeting cardiac fibrosis with engineered T cells H Aghajanian, T Kimura, JG Rurik, AS Hancock, MS Leibowitz, L Li, ... Nature 573 (7774), 430-433, 2019 | 479 | 2019 |
Targeting cardiac fibrosis with engineered T cells H Aghajanian, T Kimura, JG Rurik, AS Hancock, MS Leibowitz, L Li, ... Nature 573 (7774), 430-433, 2019 | 479 | 2019 |
Transcriptional and cellular diversity of the human heart NR Tucker, M Chaffin, SJ Fleming, AW Hall, VA Parsons, KC Bedi Jr, ... Circulation 142 (5), 466-482, 2020 | 353 | 2020 |
Suppression of detyrosinated microtubules improves cardiomyocyte function in human heart failure CY Chen, MA Caporizzo, K Bedi, A Vite, AI Bogush, P Robison, JG Heffler, ... Nature medicine 24 (8), 1225-1233, 2018 | 211 | 2018 |
Mitochondrial protein hyperacetylation in the failing heart JL Horton, OJ Martin, L Lai, NM Riley, AL Richards, RB Vega, TC Leone, ... JCI insight 1 (2), 2016 | 205 | 2016 |
Myocardial gene expression signatures in human heart failure with preserved ejection fraction VS Hahn, H Knutsdottir, X Luo, K Bedi, KB Margulies, SM Haldar, ... Circulation 143 (2), 120-134, 2021 | 149 | 2021 |
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy M Chaffin, I Papangeli, B Simonson, AD Akkad, MC Hill, A Arduini, ... Nature 608 (7921), 174-180, 2022 | 133 | 2022 |
Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2–Mediated Myocarditis NR Tucker, M Chaffin, KC Bedi Jr, I Papangeli, AD Akkad, A Arduini, ... Circulation 142 (7), 708-710, 2020 | 110 | 2020 |
Cardiomyocyte‐specific telomere shortening is a distinct signature of heart failure in humans M Sharifi‐Sanjani, NM Oyster, ED Tichy, KC Bedi Jr, O Harel, ... Journal of the American Heart Association 6 (9), e005086, 2017 | 96 | 2017 |
C-type natriuretic peptide co-ordinates cardiac structure and function AJ Moyes, SM Chu, AA Aubdool, MS Dukinfield, KB Margulies, KC Bedi Jr, ... European heart journal 41 (9), 1006-1020, 2020 | 69 | 2020 |
Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes PP Shah, W Lv, JH Rhoades, A Poleshko, D Abbey, MA Caporizzo, ... Cell Stem Cell 28 (5), 938-954. e9, 2021 | 68 | 2021 |
Nuclear deformation guides chromatin reorganization in cardiac development and disease B Seelbinder, S Ghosh, SE Schneider, AK Scott, AG Berman, CJ Goergen, ... Nature biomedical engineering 5 (12), 1500-1516, 2021 | 50 | 2021 |
Quantitative subcellular acyl-CoA analysis reveals distinct nuclear metabolism and isoleucine-dependent histone propionylation S Trefely, K Huber, J Liu, M Noji, S Stransky, J Singh, MT Doan, CD Lovell, ... Molecular cell 82 (2), 447-462. e6, 2022 | 46 | 2022 |
Truncated titin proteins in dilated cardiomyopathy Q McAfee, CY Chen, Y Yang, MA Caporizzo, M Morley, A Babu, S Jeong, ... Science translational medicine 13 (618), eabd7287, 2021 | 46 | 2021 |
Myocardial metabolomics of human heart failure with preserved ejection fraction VS Hahn, C Petucci, MS Kim, KC Bedi Jr, H Wang, S Mishra, N Koleini, ... Circulation 147 (15), 1147-1161, 2023 | 41 | 2023 |
Depletion of vasohibin 1 speeds contraction and relaxation in failing human cardiomyocytes CY Chen, AK Salomon, MA Caporizzo, S Curry, NA Kelly, K Bedi, ... Circulation research 127 (2), e14-e27, 2020 | 38 | 2020 |
Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure D Murashige, JW Jung, MD Neinast, MG Levin, Q Chu, JP Lambert, ... Cell metabolism 34 (11), 1749-1764. e7, 2022 | 33 | 2022 |
Integrated landscape of cardiac metabolism in end-stage human nonischemic dilated cardiomyopathy E Flam, C Jang, D Murashige, Y Yang, MP Morley, S Jung, DS Kantner, ... Nature cardiovascular research 1 (9), 817-829, 2022 | 32 | 2022 |
S-nitrosylation of histone deacetylase 2 by neuronal nitric oxide synthase as a mechanism of diastolic dysfunction S Yoon, M Kim, H Lee, G Kang, K Bedi, KB Margulies, R Jain, KI Nam, ... Circulation 143 (19), 1912-1925, 2021 | 30 | 2021 |