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Rajith Bhaskaran
Rajith Bhaskaran
Principal Scientist
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Year
SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin
G Ferone, JY Song, KD Sutherland, R Bhaskaran, K Monkhorst, ...
Cancer cell 30 (4), 519-532, 2016
1942016
Transcription factor NFIB is a driver of small cell lung cancer progression in mice and marks metastatic disease in patients
EA Semenova, M Kwon, K Monkhorst, JY Song, R Bhaskaran, ...
Cell reports 16 (3), 631-643, 2016
1252016
BSA nanoparticle loaded atorvastatin calcium-a new facet for an old drug
A C. H, A Ravindran
PloS one 9 (2), e86317, 2014
782014
Applied & Translational Genomics
CGP Doss, B Rajith, N Garwasis, PR Mathew, AS Raju
75*2012
TRIM28 haploinsufficiency predisposes to Wilms tumor
IJ Diets, J Hoyer, AB Ekici, B Popp, N Hoogerbrugge, SV van Reijmersdal, ...
International journal of cancer 145 (4), 941-951, 2019
522019
Path to facilitate the prediction of functional amino acid substitutions in red blood cell disorders–a computational approach
B Rajith
PLoS One 6 (9), e24607, 2011
482011
Structural signature of the G719S-T790M double mutation in the EGFR kinase domain and its response to inhibitors
C Chakraborty, NS N, SK Ali, H Zhu
Scientific reports 4 (1), 5868, 2014
472014
Computational Refinement of Functional Single Nucleotide Polymorphisms Associated with ATM Gene
C George Priya Doss, B Rajith
PLoS One 7 (4), e34573, 2012
422012
Tumor heterogeneity underlies differential cisplatin sensitivity in mouse models of small-cell lung cancer
F Böttger, EA Semenova, JY Song, G Ferone, J van der Vliet, M Cozijnsen, ...
Cell reports 27 (11), 3345-3358. e4, 2019
402019
Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice
J Badhai, GK Pandey, JY Song, O Krijgsman, R Bhaskaran, ...
Journal of Experimental Medicine 217 (6), 2020
332020
In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach
CGP Doss, B Rajith, C Chakraboty, V Balaji, R Magesh, B Gowthami, ...
Molecular BioSystems 10 (3), 421-436, 2014
302014
A new insight into structural and functional impact of single-nucleotide polymorphisms in PTEN gene
C George Priya Doss, B Rajith
Cell biochemistry and biophysics 66 (2), 249-263, 2013
242013
In silico analysis of prion protein mutants: A comparative study by molecular dynamics approach
C George Priya Doss, B Rajith, R Rajasekaran, J Srajan, ...
Cell biochemistry and biophysics 67, 1307-1318, 2013
132013
Predicting the impact of deleterious mutations in the protein kinase domain of FGFR2 in the context of function, structure, and pathogenesis—a bioinformatics approach
B Rajith, C Chakraborty
Applied biochemistry and biotechnology 170, 1853-1870, 2013
112013
Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development
A Alendar, JP Lambooij, R Bhaskaran, C Lancini, JY Song, H van Vugt, ...
PLoS One 15 (5), e0233394, 2020
102020
MammaPrint and BluePrint comprehensively capture the cancer hallmarks in early‐stage breast cancer patients
JC Haan, R Bhaskaran, A Ellappalayam, Y Bijl, CJ Griffioen, E Lujinovic, ...
Genes, Chromosomes and Cancer 61 (3), 148-160, 2022
82022
A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis
P Krimpenfort, M Snoek, JP Lambooij, JY Song, R van der Weide, ...
Nature Communications 10 (1), 1425, 2019
82019
In silico discrimination of nsSNPs in hTERT gene by means of local DNA sequence context and regularity
CGP Doss, C Chakraborty, B Rajith, N Nagasundaram
Journal of molecular modeling 19, 3517-3527, 2013
82013
Influence of the SNPs on the structural stability of CBS protein: Insight from molecular dynamics simulations
C George Priya Doss, B Rajith, R Magesh, A Ashish Kumar
Frontiers in biology 9, 504-518, 2014
62014
Disease-causing mutation in extracellular and intracellular domain of FGFR1 protein: computational approach
B Rajith, C George Priya Doss
Applied biochemistry and biotechnology 169, 1659-1671, 2013
52013
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