Rajith Bhaskaran
Rajith Bhaskaran
Principal Scientist
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SOX2 is the determining oncogenic switch in promoting lung squamous cell carcinoma from different cells of origin
G Ferone, JY Song, KD Sutherland, R Bhaskaran, K Monkhorst, ...
Cancer cell 30 (4), 519-532, 2016
Transcription factor NFIB is a driver of small cell lung cancer progression in mice and marks metastatic disease in patients
EA Semenova, M Kwon, K Monkhorst, JY Song, R Bhaskaran, ...
Cell reports 16 (3), 631-643, 2016
Applied & Translational Genomics
CGP Doss, B Rajith, N Garwasis, PR Mathew, AS Raju
BSA nanoparticle loaded atorvastatin calcium-a new facet for an old drug
A C. H, A Ravindran
PloS one 9 (2), e86317, 2014
TRIM28 haploinsufficiency predisposes to Wilms tumor
IJ Diets, J Hoyer, AB Ekici, B Popp, N Hoogerbrugge, SV van Reijmersdal, ...
International journal of cancer 145 (4), 941-951, 2019
Structural signature of the G719S-T790M double mutation in the EGFR kinase domain and its response to inhibitors
C Chakraborty, NS N, SK Ali, H Zhu
Scientific reports 4 (1), 5868, 2014
Path to facilitate the prediction of functional amino acid substitutions in red blood cell disorders–a computational approach
B Rajith
PLoS One 6 (9), e24607, 2011
Tumor heterogeneity underlies differential cisplatin sensitivity in mouse models of small-cell lung cancer
F Böttger, EA Semenova, JY Song, G Ferone, J van der Vliet, M Cozijnsen, ...
Cell reports 27 (11), 3345-3358. e4, 2019
Computational Refinement of Functional Single Nucleotide Polymorphisms Associated with ATM Gene
C George Priya Doss, B Rajith
PLoS One 7 (4), e34573, 2012
Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice
J Badhai, GK Pandey, JY Song, O Krijgsman, R Bhaskaran, ...
Journal of Experimental Medicine 217 (6), 2020
In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach
CGP Doss, B Rajith, C Chakraboty, V Balaji, R Magesh, B Gowthami, ...
Molecular BioSystems 10 (3), 421-436, 2014
A new insight into structural and functional impact of single-nucleotide polymorphisms in PTEN gene
C George Priya Doss, B Rajith
Cell biochemistry and biophysics 66 (2), 249-263, 2013
In silico analysis of prion protein mutants: A comparative study by molecular dynamics approach
C George Priya Doss, B Rajith, R Rajasekaran, J Srajan, ...
Cell biochemistry and biophysics 67, 1307-1318, 2013
MammaPrint and BluePrint comprehensively capture the cancer hallmarks in early‐stage breast cancer patients
JC Haan, R Bhaskaran, A Ellappalayam, Y Bijl, CJ Griffioen, E Lujinovic, ...
Genes, Chromosomes and Cancer 61 (3), 148-160, 2022
Gene expression regulation by the Chromodomain helicase DNA-binding protein 9 (CHD9) chromatin remodeler is dispensable for murine development
A Alendar, JP Lambooij, R Bhaskaran, C Lancini, JY Song, H van Vugt, ...
PLoS One 15 (5), e0233394, 2020
Predicting the impact of deleterious mutations in the protein kinase domain of FGFR2 in the context of function, structure, and pathogenesis—a bioinformatics approach
B Rajith, C Chakraborty
Applied biochemistry and biotechnology 170, 1853-1870, 2013
A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis
P Krimpenfort, M Snoek, JP Lambooij, JY Song, R van der Weide, ...
Nature Communications 10 (1), 1425, 2019
In silico discrimination of nsSNPs in hTERT gene by means of local DNA sequence context and regularity
CGP Doss, C Chakraborty, B Rajith, N Nagasundaram
Journal of molecular modeling 19, 3517-3527, 2013
Influence of the SNPs on the structural stability of CBS protein: Insight from molecular dynamics simulations
C George Priya Doss, B Rajith, R Magesh, A Ashish Kumar
Frontiers in biology 9, 504-518, 2014
Disease-causing mutation in extracellular and intracellular domain of FGFR1 protein: computational approach
B Rajith, C George Priya Doss
Applied biochemistry and biotechnology 169, 1659-1671, 2013
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