| Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM TV Lanz, RC Brewer, PP Ho, JS Moon, KM Jude, D Fernandez, ... Nature 603 (7900), 321-327, 2022 | 463 | 2022 |
| De novo design of potent and selective mimics of IL-2 and IL-15 DA Silva, S Yu, UY Ulge, JB Spangler, KM Jude, C Labão-Almeida, LR Ali, ... Nature 565 (7738), 186-191, 2019 | 414 | 2019 |
| CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer K Weiskopf, NS Jahchan, PJ Schnorr, S Cristea, AM Ring, RL Maute, ... The Journal of clinical investigation 126 (7), 2610-2620, 2016 | 394 | 2016 |
| Structural basis for chemokine recognition and activation of a viral G protein–coupled receptor JS Burg, JR Ingram, AJ Venkatakrishnan, KM Jude, A Dukkipati, ... Science 347 (6226), 1113-1117, 2015 | 315 | 2015 |
| Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes JT Sockolosky, E Trotta, G Parisi, L Picton, LL Su, AC Le, A Chhabra, ... Science 359 (6379), 1037-1042, 2018 | 291 | 2018 |
| Structural basis for Notch1 engagement of Delta-like 4 VC Luca, KM Jude, NW Pierce, MV Nachury, S Fischer, KC Garcia Science 347 (6224), 847-853, 2015 | 288 | 2015 |
| Isolation of a structural mechanism for uncoupling T cell receptor signaling from peptide-MHC binding LV Sibener, RA Fernandes, EM Kolawole, CB Carbone, F Liu, D McAffee, ... Cell 174 (3), 672-687. e27, 2018 | 260 | 2018 |
| Antibodies to interleukin-2 elicit selective T cell subset potentiation through distinct conformational mechanisms JB Spangler, J Tomala, VC Luca, KM Jude, S Dong, AM Ring, P Votavova, ... Immunity 42 (5), 815-825, 2015 | 233 | 2015 |
| Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 217 | 2022 |
| A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism E Trotta, PH Bessette, SL Silveria, LK Ely, KM Jude, DT Le, CR Holst, ... Nature medicine 24 (7), 1005-1014, 2018 | 187 | 2018 |
| Structure of the IFNγ receptor complex guides design of biased agonists JL Mendoza, NK Escalante, KM Jude, J Sotolongo Bellon, L Su, ... Nature 567 (7746), 56-60, 2019 | 114 | 2019 |
| Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle KM Jude, SK Wright, C Tu, DN Silverman, RE Viola, DW Christianson Biochemistry 41 (8), 2485-2491, 2002 | 109 | 2002 |
| Topological control of cytokine receptor signaling induces differential effects in hematopoiesis K Mohan, G Ueda, AR Kim, KM Jude, JA Fallas, Y Guo, M Hafer, Y Miao, ... Science 364 (6442), eaav7532, 2019 | 107 | 2019 |
| The IFN-λ-IFN-λR1-IL-10Rβ complex reveals structural features underlying type III IFN functional plasticity JL Mendoza, WM Schneider, HH Hoffmann, K Vercauteren, KM Jude, ... Immunity 46 (3), 379-392, 2017 | 103 | 2017 |
| Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with “two-prong” inhibitors reveal the molecular basis of high affinity KM Jude, AL Banerjee, MK Haldar, S Manokaran, B Roy, S Mallik, ... Journal of the American Chemical Society 128 (9), 3011-3018, 2006 | 100 | 2006 |
| Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells CR Glassman, YK Mathiharan, KM Jude, L Su, O Panova, PJ Lupardus, ... Cell 184 (4), 983-999. e24, 2021 | 87 | 2021 |
| Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation CR Glassman, N Tsutsumi, RA Saxton, PJ Lupardus, KM Jude, KC Garcia Science 376 (6589), 163-169, 2022 | 82 | 2022 |
| Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling N Tsutsumi, S Mukherjee, D Waghray, CY Janda, KM Jude, Y Miao, ... elife 9, e58464, 2020 | 79 | 2020 |
| Structure of a 129Xe-Cryptophane Biosensor Complexed with Human Carbonic Anhydrase II JA Aaron, JM Chambers, KM Jude, L Di Costanzo, IJ Dmochowski, ... Journal of the American Chemical Society 130 (22), 6942-6943, 2008 | 78 | 2008 |
| Structural analysis of charge discrimination in the binding of inhibitors to human carbonic anhydrases I and II DK Srivastava, KM Jude, AL Banerjee, M Haldar, S Manokaran, J Kooren, ... Journal of the American Chemical Society 129 (17), 5528-5537, 2007 | 74 | 2007 |
K. Christopher GarciaStanford University/HHMIVerified email at stanford.edu
