| Opioid receptors: Structural and mechanistic insights into pharmacology and signaling Y Shang, M Filizola European journal of pharmacology 763, 206-213, 2015 | 111 | 2015 |
| Mechanistic insights into the allosteric modulation of opioid receptors by sodium ions Y Shang, V LeRouzic, S Schneider, P Bisignano, GW Pasternak, ... Biochemistry 53 (31), 5140-5149, 2014 | 103 | 2014 |
| RUC-4 A Novel αIIbβ3 Antagonist for Prehospital Therapy of Myocardial Infarction J Li, S Vootukuri, Y Shang, A Negri, J Jiang, M Nedelman, TG Diacovo, ... Arteriosclerosis, thrombosis, and vascular biology 34 (10), 2321-2329, 2014 | 85 | 2014 |
| Discovery, Synthesis, and Molecular Pharmacology of Selective Positive Allosteric Modulators of the δ-Opioid Receptor NT Burford, KE Livingston, M Canals, MR Ryan, LML Budenholzer, Y Han, ... Journal of medicinal chemistry 58 (10), 4220-4229, 2015 | 71 | 2015 |
| Proposed mode of binding and action of positive allosteric modulators at opioid receptors Y Shang, HR Yeatman, D Provasi, A Alt, A Christopoulos, M Canals, ... ACS chemical biology 11 (5), 1220-1229, 2016 | 70 | 2016 |
| Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the μ-Opioid Receptor P Bisignano, NT Burford, Y Shang, B Marlow, KE Livingston, AM Fenton, ... Journal of chemical information and modeling 55 (9), 1836-1843, 2015 | 40 | 2015 |
| Insights into the function of opioid receptors from molecular dynamics simulations of available crystal structures KA Marino, Y Shang, M Filizola British journal of pharmacology 175 (14), 2834-2845, 2018 | 35 | 2018 |
| Novel pure αVβ3 integrin antagonists that do not induce receptor extension, prime the receptor, or enhance angiogenesis at low concentrations J Li, Y Fukase, Y Shang, W Zou, JM Muñoz-Félix, L Buitrago, ... ACS Pharmacology & Translational Science 2 (6), 387-401, 2019 | 24 | 2019 |
| Improving the description of salt bridge strength and geometry in a Generalized Born model Y Shang, H Nguyen, L Wickstrom, A Okur, C Simmerling Journal of Molecular Graphics and Modelling 29 (5), 676-684, 2011 | 20 | 2011 |
| αIIbβ3 binding to a fibrinogen fragment lacking the γ-chain dodecapeptide is activation dependent and EDTA inducible H Zafar, Y Shang, J Li, GA David III, JP Fernandez, H Molina, M Filizola, ... Blood Advances 1 (7), 417-428, 2017 | 16 | 2017 |
| Molecular dynamics applied in drug discovery: the case of HIV-1 protease Y Shang, C Simmerling Computational Drug Discovery and Design, 527-549, 2012 | 15 | 2012 |
| Development of a Pure Small Molecule αVβ3 Antagonist J Li, Y Fukase, Y Shang, W Zou, R Hara, Y Tanaka, R Okamoto, T Yasui, ... Blood 130, 548, 2017 | | 2017 |
| Development of a Pure Small Molecule aV ss 3 Antagonist J Li, Y Fukase, Y Shang, W Zou, R Hara, Y Tanaka, R Okamoto, T Yasui, ... BLOOD 130, 2017 | | 2017 |
| Binding Pockets and Poses of Allosteric Modulators of Opioid Receptors Identified by Metadynamics Y Shang, HR Yeatman, N Burford, K Livingston, P Bisignano, J Traynor, ... Biophysical Journal 108 (2), 415a, 2015 | | 2015 |
| Development of a novel class alpha IIb beta 3 receptor antagonist RUC-4 as anti-platelet aggregation agent for myocardial infarction JK Jiang, JG McCoy, J Li, S Vootukuri, M Shen, Y Shang, CA LeClair, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 248, 2014 | | 2014 |
| A Molecular-Level Investigation of the Effect of Sodium Ions on the Binding of Opioid Ligands to their Receptors Y Shang, V Le Rouzic, GW Pasternak, M Filizola Biophysical Journal 106 (2), 105a, 2014 | | 2014 |
| Computer-aided Drug Design Targeting Aspartic Proteases Y Shang State University of New York at Stony Brook, 2013 | | 2013 |
| Simulations of spin-labeled HIV-1 protease exhibit diverse flap dynamics due to sequence polymorphism Y Shang, F Ding, C Simmerling ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | | 2011 |
| Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the?-opioid receptor NT Burford, KE Livingston, M Canals, MR Ryan, LML Budenholzer, Y Han, ... Journal of Medicinal Chemistry 58 (10), 0 | | |
| Tuesday, February 10, 2015 415a Y Shang, HR Yeatman, N Burford, K Livingston, P Bisignano, J Traynor, ... | | |
Marta FilizolaDean and Professor at Icahn School of Medicine at Mount SinaiVerified email at mssm.edu
