متابعة
Yung-Hsin Huang
Yung-Hsin Huang
NCI K00 Postdoctoral Fellow, Stanford University
بريد إلكتروني تم التحقق منه على stanford.edu
عنوان
عدد مرات الاقتباسات
عدد مرات الاقتباسات
السنة
DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells
X Zhang, J Su, M Jeong, M Ko, Y Huang, HJ Park, A Guzman, Y Lei, ...
Nature genetics 48 (9), 1014-1023, 2016
2512016
Mutant NPM1 maintains the leukemic state through HOX expression
L Brunetti, MC Gundry, D Sorcini, AG Guzman, YH Huang, ...
Cancer cell 34 (3), 499-512. e9, 2018
2422018
DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A
YH Huang, J Su, Y Lei, L Brunetti, MC Gundry, X Zhang, M Jeong, W Li, ...
Genome biology 18 (1), 176, 2017
2172017
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein
Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang, Y Zhou, W Li, ...
Nature communications 8 (1), 16026, 2017
2102017
Homeobox oncogene activation by pan-cancer DNA hypermethylation
JS Su, YH Huang, XC Cui, X Wang, X Zhang, Y Lei, J Xu, X Lin, K Chen, ...
Genome Biology, 2018
1082018
Large DNA methylation nadirs anchor chromatin loops maintaining hematopoietic stem cell identity
X Zhang, M Jeong, X Huang, XQ Wang, X Wang, W Zhou, MS Shamim, ...
Molecular cell 78 (3), 506-521. e6, 2020
712020
Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer
B Bissig-Choisat, C Kettlun-Leyton, XD Legras, B Zorman, M Barzi, ...
Journal of hepatology 65 (2), 325-333, 2016
682016
DNA methylation and de-methylation using hybrid site-targeting proteins
Y Lei, YH Huang, MA Goodell
Genome biology 19, 1-12, 2018
652018
Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners
JE Sandoval, YH Huang, A Muise, MA Goodell, NO Reich
Journal of Biological Chemistry 294 (13), 4898-4910, 2019
642019
Systematic Profiling of DNMT3A Variants Reveals Protein Instability Mediated by the DCAF8 E3 Ubiquitin Ligase Adaptor
YH Huang, CW Chen, V Sundaramurthy, M Słabicki, D Hao, CJ Watson, ...
Cancer discovery 12 (1), 220-235, 2022
332022
Perturbed hematopoiesis in individuals with germline DNMT3A overgrowth Tatton-Brown-Rahman syndrome
A Tovy, C Rosas, AS Gaikwad, G Medrano, L Zhang, JM Reyes, ...
Haematologica 107 (4), 887, 2022
162022
Constitutive loss of DNMT3A causes morbid obesity through misregulation of adipogenesis
A Tovy, JM Reyes, L Zhang, YH Huang, C Rosas, AC Daquinag, ...
Elife 11, e72359, 2022
142022
A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells
JB Hong, FJ Chou, AT Ku, HH Fan, TL Lee, YH Huang, TL Yang, IC Su, ...
Plos one 9 (2), e89396, 2014
72014
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nat Commun 8: 16026
Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang, Y Zhou, W Li, ...
52017
Nearly a Third of Clonal Hematopoiesis-Associated DNMT3A Mutations Reduce Protein Stability and May be Associated with Poorer Prognosis
YH Huang, A Tovy, V Sundaramurthy, J Su, J Hsu, L He, A Guzman, ...
Blood 132, 1315, 2018
22018
Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nat Commun. 2017; 8: 16026
Y Lei, X Zhang, J Su, M Jeong, MC Gundry, YH Huang
2
Clonal Competition: Cisplatin Treatment Drives Dominance of TP53-over Tet2-Mutant Stem Cell Clones
K Wohlan, L Brunetti, JI Hsu, KA Matatall, RL Murdaugh, L Zhang, ...
Blood 140 (Supplement 1), 8590-8591, 2022
2022
A nucleolus-predominant piggyBac transposase increases transposition efficiency in human cancer cells
JB Hong, FJ Chou, AT Ku, HH Fan, TL Lee, YH Huang, IC Su, YT Chen
Cancer Research 74 (19_Supplement), 3495-3495, 2014
2014
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مقالات 1–18