| Pan-cancer landscape of homologous recombination deficiency L Nguyen, J WM Martens, A Van Hoeck, E Cuppen Nature communications 11 (1), 5584, 2020 | 292 | 2020 |
| The genomic landscape of metastatic breast cancer highlights changes in mutation and signature frequencies L Angus, M Smid, SM Wilting, J van Riet, A Van Hoeck, L Nguyen, ... Nature genetics 51 (10), 1450-1458, 2019 | 280 | 2019 |
| Patient-derived ovarian cancer organoids mimic clinical response and exhibit heterogeneous inter-and intrapatient drug responses CJ de Witte, JE Valle-Inclan, N Hami, K Lõhmussaar, O Kopper, ... Cell reports 31 (11), 2020 | 172 | 2020 |
| Nanoparticle size influences antigen retention and presentation in lymph node follicles for humoral immunity YN Zhang, J Lazarovits, W Poon, B Ouyang, LNM Nguyen, BR Kingston, ... Nano letters 19 (10), 7226-7235, 2019 | 165 | 2019 |
| Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P‐glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2 … S Chuan Tang, LN Nguyen, RW Sparidans, E Wagenaar, JH Beijnen, ... International journal of cancer 134 (6), 1484-1494, 2014 | 149 | 2014 |
| Secretion-mediated STAT3 activation promotes self-renewal of glioma stem-like cells during hypoxia DA Almiron Bonnin, MC Havrda, MC Lee, H Liu, Z Zhang, LN Nguyen, ... Oncogene 37 (8), 1107-1118, 2018 | 85 | 2018 |
| The hematopoietic transcription factors RUNX1 and ERG prevent AML1-ETO oncogene overexpression and onset of the apoptosis program in t (8; 21) AMLs A Mandoli, AA Singh, KHM Prange, E Tijchon, M Oerlemans, R Dirks, ... Cell reports 17 (8), 2087-2100, 2016 | 67 | 2016 |
| Pan-cancer whole-genome comparison of primary and metastatic solid tumours F Martínez-Jiménez, A Movasati, SR Brunner, L Nguyen, P Priestley, ... Nature 618 (7964), 333-341, 2023 | 64 | 2023 |
| WM Martens J, Van Hoeck A, Cuppen E L Nguyen Pan-cancer landscape of homologous recombination deficiency. Nat Commun 11 …, 2020 | 58 | 2020 |
| The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression NQ Liu, M Ter Huurne, LN Nguyen, T Peng, SY Wang, JB Studd, O Joshi, ... Nature communications 8 (1), 14418, 2017 | 56 | 2017 |
| A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding A Lewis, L Freeman-Mills, E de la Calle-Mustienes, RM Giráldez-Pérez, ... Cell reports 8 (4), 983-990, 2014 | 54 | 2014 |
| Genome-wide binding of MBD2 reveals strong preference for highly methylated loci R Menafra, AB Brinkman, F Matarese, G Franci, SJJ Bartels, L Nguyen, ... PloS one 9 (6), e99603, 2014 | 54 | 2014 |
| The oncofusion protein FUS–ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t (16; 21) acute myeloid leukemia AM Sotoca, KHM Prange, B Reijnders, A Mandoli, LN Nguyen, ... Oncogene 35 (15), 1965-1976, 2016 | 48 | 2016 |
| Macrophages actively transport nanoparticles in tumors after extravasation ZP Lin, LNM Nguyen, B Ouyang, P MacMillan, J Ngai, BR Kingston, ... ACS nano 16 (4), 6080-6092, 2022 | 45 | 2022 |
| A quantitative proteomics tool to identify DNA–protein interactions in primary cells or blood NC Hubner, LN Nguyen, NC Hornig, HG Stunnenberg Journal of proteome research 14 (2), 1315-1329, 2015 | 42 | 2015 |
| Machine learning-based tissue of origin classification for cancer of unknown primary diagnostics using genome-wide mutation features L Nguyen, A Van Hoeck, E Cuppen Nature communications 13 (1), 4013, 2022 | 35 | 2022 |
| Liquid chromatography–tandem mass spectrometric assay for the ALK inhibitor crizotinib in mouse plasma RW Sparidans, SC Tang, LN Nguyen, AH Schinkel, JHM Schellens, ... Journal of Chromatography B 905, 150-154, 2012 | 29 | 2012 |
| The exit of nanoparticles from solid tumours LNM Nguyen, ZP Lin, S Sindhwani, P MacMillan, SM Mladjenovic, ... Nature Materials 22 (10), 1261-1272, 2023 | 20 | 2023 |
| A proposed mathematical description of in vivo nanoparticle delivery JLY Wu, BP Stordy, LNM Nguyen, CP Deutschman, WCW Chan Advanced Drug Delivery Reviews 189, 114520, 2022 | 14 | 2022 |
| Reactivity of human AGO2 monoclonal antibody 11A9 with the SWI/SNF complex: A case study for rigorously defining antibody selectivity RAPM van Eijl, T van den Brand, LN Nguyen, KW Mulder Scientific Reports 7 (1), 7278, 2017 | 13 | 2017 |
Koen PrangeAcademic Medical Center - University of AmsterdamVerified email at amc.uva.nl
