| Novel peptide nanoparticle–biased antagonist of CCR3 blocks eosinophil recruitment and airway hyperresponsiveness M Grozdanovic, KG Laffey, H Abdelkarim, B Hitchinson, A Harijith, ... Journal of Allergy and Clinical Immunology 143 (2), 669-680. e12, 2019 | 66 | 2019 |
| Biased antagonism of CXCR4 avoids antagonist tolerance B Hitchinson, JM Eby, X Gao, F Guite-Vinet, JJ Ziarek, H Abdelkarim, ... Science signaling 11 (552), eaat2214, 2018 | 45 | 2018 |
| SPHK2-generated S1P in CD11b+ macrophages blocks STING to suppress the inflammatory function of alveolar macrophages JC Joshi, B Joshi, I Rochford, S Rayees, MZ Akhter, S Baweja, KR Chava, ... Cell reports 30 (12), 4096-4109. e5, 2020 | 44 | 2020 |
| Design, synthesis, and biological evaluation of tetrahydroisoquinoline-based histone deacetylase 8 selective inhibitors TY Taha, SM Aboukhatwa, RC Knopp, N Ikegaki, H Abdelkarim, ... ACS Medicinal Chemistry Letters 8 (8), 824-829, 2017 | 37 | 2017 |
| α-Synuclein interacts directly but reversibly with psychosine: implications for α-synucleinopathies H Abdelkarim, MS Marshall, G Scesa, RA Smith, E Rue, J Marshall, ... Scientific reports 8 (1), 12462, 2018 | 30 | 2018 |
| A chimeric SERM–histone deacetylase inhibitor approach to breast cancer therapy HK Patel, MI Siklos, H Abdelkarim, EL Mendonca, A Vaidya, PA Petukhov, ... ChemMedChem 9 (3), 602-613, 2014 | 27 | 2014 |
| Novel histone deacetylase 8 ligands without a zinc chelating group: Exploring an ‘upside-down’binding pose AS Vaidya, R Neelarapu, A Madriaga, H Bai, E Mendonca, H Abdelkarim, ... Bioorganic & medicinal chemistry letters 22 (21), 6621-6627, 2012 | 26 | 2012 |
| Functional and structural consequences of chemokine (CXC motif) receptor 4 activation with cognate and non-cognate agonists JM Eby, H Abdelkarim, LJ Albee, A Tripathi, X Gao, BF Volkman, ... Molecular and cellular biochemistry 434, 143-151, 2017 | 22 | 2017 |
| Design, synthesis, modeling, biological evaluation and photoaffinity labeling studies of novel series of photoreactive benzamide probes for histone deacetylase 2 AS Vaidya, B Karumudi, E Mendonca, A Madriaga, H Abdelkarim, ... Bioorganic & medicinal chemistry letters 22 (15), 5025-5030, 2012 | 21 | 2012 |
| Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1 S Das, RS Nair, R Mishra, G Sondarva, N Viswakarma, H Abdelkarim, ... Oncogene 38 (19), 3569-3584, 2019 | 17* | 2019 |
| The hypervariable region of K-Ras4B governs molecular recognition and function H Abdelkarim, A Banerjee, P Grudzien, N Leschinsky, M Abushaer, ... International journal of molecular sciences 20 (22), 5718, 2019 | 14 | 2019 |
| Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine‐based Histone Deacetylase Inhibitors H Abdelkarim, R Neelarapu, A Madriaga, AS Vaidya, I Kastrati, ... ChemMedChem 12 (24), 2030-2043, 2017 | 13 | 2017 |
| Photoreactive “nanorulers” detect a novel conformation of full length HDAC3-SMRT complex in solution H Abdelkarim, M Brunsteiner, R Neelarapu, H Bai, A Madriaga, ... ACS chemical biology 8 (11), 2538-2549, 2013 | 13 | 2013 |
| The dynamic nature of the K-Ras/calmodulin complex can be altered by oncogenic mutations H Abdelkarim, N Leschinsky, H Jang, A Banerjee, R Nussinov, ... Current Opinion in Structural Biology 71, 164-170, 2021 | 9 | 2021 |
| Partial agonist activity of α1-adrenergic receptor antagonists for chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3 X Gao, H Abdelkarim, LJ Albee, BF Volkman, V Gaponenko, ... PloS one 13 (9), e0204041, 2018 | 9 | 2018 |
| Advances in NMR methods to identify allosteric sites and allosteric ligands H Abdelkarim, B Hitchinson, A Banerjee, V Gaponenko Protein Allostery in Drug Discovery, 171-186, 2019 | 5 | 2019 |
| Correction to design, synthesis, and biological evaluation of tetrahydroisoquinoline-based histone deacetylase 8 selective inhibitors TY Taha, SM Aboukhatwa, RC Knopp, N Ikegaki, H Abdelkarim, ... ACS Medicinal Chemistry Letters 10 (9), 1358-1358, 2019 | 3 | 2019 |
| NMR resonance assignment and structure prediction of the C-terminal domain of the microtubule end-binding protein 3 H Abdelkarim, B Hitchinson, X Qu, A Banerjee, YA Komarova, ... Plos one 15 (5), e0232338, 2020 | 1 | 2020 |
| Abstract IA21: Preventing KRAS processing A Maciag, Y Yang, D Turner, M Dyba, V Kumari, B Smith, L Fan, S Gysin, ... Molecular Cancer Research 18 (5_Supplement), IA21-IA21, 2020 | 1 | 2020 |
| A novel biased antagonist of the eotaxin-CCR3 pathway in eosinophils MM Grozdanovic, LK Rousslang, H Abdelkarim, KG Laffey, B Hitchinson, ... Journal of Allergy and Clinical Immunology 139 (2), AB163, 2017 | 1 | 2017 |
