New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis NA Alsaif, MA Dahab, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Bioorganic Chemistry 110, 104807, 2021 | 74 | 2021 |
Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers MM Alanazi, IH Eissa, NA Alsaif, AJ Obaidullah, WA Alanazi, AF Alasmari, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1760-1782, 2021 | 69 | 2021 |
New bis ([1, 2, 4] triazolo)[4, 3-a: 3′, 4′-c] quinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers: Design, synthesis, in silico studies, and anticancer … MM Alanazi, HA Mahdy, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Bioorganic Chemistry 112, 104949, 2021 | 64 | 2021 |
New quinoxaline-based VEGFR-2 inhibitors: Design, synthesis, and antiproliferative evaluation with in silico docking, ADMET, toxicity, and DFT studies MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... RSC advances 11 (48), 30315-30328, 2021 | 52 | 2021 |
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2 HM Alkahtani, AN Abdalla, AJ Obaidullah, MM Alanazi, AA Almehizia, ... Bioorganic Chemistry 95, 103461, 2020 | 48 | 2020 |
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, AA Al-Mehizia, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 1093-1114, 2021 | 44 | 2021 |
Discovery of new quinoxaline-based derivatives as anticancer agents and potent VEGFR-2 inhibitors: Design, synthesis, and in silico study MM Alanazi, H Elkady, NA Alsaif, AJ Obaidullah, WA Alanazi, ... Journal of Molecular Structure 1253, 132220, 2022 | 37 | 2022 |
Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies MM Alanazi, A Elwan, NA Alsaif, AJ Obaidullah, HM Alkahtani, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1732-1750, 2021 | 37 | 2021 |
Recent progress in chemical approaches for the development of novel neuraminidase inhibitors A Mahal, M Duan, DS Zinad, RK Mohapatra, AJ Obaidullah, X Wei, ... RSC advances 11 (3), 1804-1840, 2021 | 36 | 2021 |
Histological assessment, anti-quorum sensing, and anti-biofilm activities of Dioon spinulosum extract: in vitro and in vivo approach E Elekhnawy, WA Negm, M El-Aasr, AA Kamer, M Alqarni, GES Batiha, ... Scientific Reports 12 (1), 180, 2022 | 32 | 2022 |
Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application AM Abdelhamid, S Saber, ME Youssef, AGA Gaafar, H Eissa, ... Biomedicine & Pharmacotherapy 145, 112455, 2022 | 29 | 2022 |
Immunoinformatics-guided design of a multi-epitope vaccine based on the structural proteins of severe acute respiratory syndrome coronavirus 2 AJ Obaidullah, MM Alanazi, NA Alsaif, H Albassam, AA Almehizia, ... RSC advances 11 (29), 18103-18121, 2021 | 29 | 2021 |
Molecular Docking and Dynamics Simulation of Natural Compounds from Betel Leaves (Piper betle L.) for Investigating the Potential Inhibition of Alpha-Amylase … S Ahmed, MC Ali, RA Ruma, S Mahmud, GK Paul, MA Saleh, ... Molecules 27 (14), 4526, 2022 | 24 | 2022 |
Identification of new [1, 2, 4] triazolo [4, 3-a] quinoxalines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, anticancer evaluation, and in silico studies NA Alsaif, MS Taghour, MM Alanazi, AJ Obaidullah, WA Alanazi, ... Bioorganic & Medicinal Chemistry 46, 116384, 2021 | 23 | 2021 |
Sterculia tragacantha lindl leaf extract ameliorates STZ-induced diabetes, oxidative stress, inflammation and neuronal impairment AS Onikanni, B Lawal, AO Olusola, JO Olugbodi, S Sani, BO Ajiboye, ... Journal of Inflammation Research 14, 6749, 2021 | 22 | 2021 |
Molecular docking and dynamics studies to explore effective inhibitory peptides against the spike receptor binding domain of SARS-CoV-2 S Biswas, S Mahmud, MA Mita, S Afrose, MR Hasan, M Sultana Shimu, ... Frontiers in Molecular Biosciences 8, 791642, 2022 | 21 | 2022 |
AKT-AMPKα-mTOR-dependent HIF-1α activation is a new therapeutic target for cancer treatment: a novel approach to repositioning the antidiabetic drug sitagliptin for the … A El-Fattah, E Eslam, S Saber, ME Youssef, H Eissa, E El-Ahwany, ... Frontiers in Pharmacology 12, 720173, 2022 | 20 | 2022 |
Synthesis, anti-inflammatory, cytotoxic, and COX-1/2 inhibitory activities of cyclic imides bearing 3-benzenesulfonamide, oxime, and β-phenylalanine scaffolds: a molecular … AAM Abdel-Aziz, AS El-Azab, NA AlSaif, MM Alanazi, MA El-Gendy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 610-621, 2020 | 20 | 2020 |
Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities A Tripathi, E Martinez, AJ Obaidullah, MG Lete, M Lönnfors, D Khan, ... Journal of Biological Chemistry 294 (50), 19081-19098, 2019 | 20 | 2019 |
Synthesis, potential antitumor activity, cell cycle analysis, and multitarget mechanisms of novel hydrazones incorporating a 4-methylsulfonylbenzene scaffold: a molecular … AAM Abdel-Aziz, AS El-Azab, NA AlSaif, AJ Obaidullah, AM Al-Obaid, ... Journal of Enzyme Inhibition and Medicinal Chemistry 36 (1), 1520-1538, 2021 | 19 | 2021 |