Emil Laust Kristoffersen
Emil Laust Kristoffersen
Assistant Professor at iNANO and MBG, Aarhus University
Verified email at
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Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage
S Juul, F Iacovelli, M Falconi, SL Kragh, B Christensen, R Frøhlich, ...
ACS nano 7 (11), 9724-9734, 2013
Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria-Causing Plasmodium Parasites Based on Enzyme Activity Measurement
S Juul, CJF Nielsen, R Labouriau, A Roy, C Tesauro, PW Jensen, ...
ACS nano 6 (12), 10676-10683, 2012
Real-time detection of TDP1 activity using a fluorophore–quencher coupled DNA-biosensor
PW Jensen, M Falconi, EL Kristoffersen, AT Simonsen, JB Cifuentes, ...
Biosensors and Bioelectronics 48, 230-237, 2013
Topoisomerase I activity and sensitivity to camptothecin in breast cancer-derived cells: a comparative study
C Tesauro, AK Simonsen, MB Andersen, KW Petersen, EL Kristoffersen, ...
BMC cancer 19, 1-15, 2019
Rolling circle RNA synthesis catalyzed by RNA
EL Kristoffersen, M Burman, A Noy, P Holliger
Elife 11, e75186, 2022
DNA-based sensor for real-time measurement of the enzymatic activity of human topoisomerase I
LB Marcussen, ML Jepsen, EL Kristoffersen, O Franch, J Proszek, YP Ho, ...
Sensors 13 (4), 4017-4028, 2013
Advantages of an optical nanosensor system for the mechanistic analysis of a novel topoisomerase I targeting drug: a case study
MB Andersen, C Tesauro, M Gonzalez, EL Kristoffersen, C Alonso, ...
Nanoscale 9 (5), 1886-1895, 2017
Real-time investigation of human topoisomerase I reaction kinetics using an optical sensor: a fast method for drug screening and determination of active enzyme concentrations
EL Kristoffersen, LA Jørgensen, O Franch, M Etzerodt, R Frøhlich, ...
Nanoscale 7 (21), 9825-9834, 2015
Optimized Detection of Plasmodium falciparum Topoisomerase I Enzyme Activity in a Complex Biological Sample by the Use of Molecular Beacons
A Givskov, EL Kristoffersen, K Vandsø, YP Ho, M Stougaard, BR Knudsen
Sensors 16 (11), 1916, 2016
Interlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events
EL Kristoffersen, A Givskov, LA Jørgensen, PW Jensen, JA W. Byl, ...
Nucleic Acids Research 45 (13), 7855-7869, 2017
Ultra-fast detection and quantification of nucleic acids by amplification-free fluorescence assay
J Uhd, L Miotke, HP Ji, M Dunaeva, GJM Pruijn, CD Jørgensen, ...
Analyst 145 (17), 5836-5844, 2020
Lups ki JR, Koch J., Desideri A., Knudsen BR, Stougaard M
PW Jensen, M Falconi, EL Kristoffersen, AT Simonsen, JB Cifuentes, ...
Biosens. Bioelectron 15, 230-237, 2013
Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing
S Juul, CJ Nielsen, R Labouriau, A Roy, C Tesauro, PW Jensen, ...
Plasmodium, 2012
Cryo-EM structure and functional landscape of an RNA polymerase ribozyme
EKS McRae, CJK Wan, EL Kristoffersen, K Hansen, E Gianni, I Gallego, ...
Proceedings of the National Academy of Sciences 121 (3), e2313332121, 2024
Molecular beacon enables combination of highly processive and highly sensitive rolling circle amplification readouts for detection of DNA-modifying enzymes
EL Kristoffersen, M Gonzalez, M Stougaard, C Tesauro
Nano Life 5 (02), 1541002, 2015
Inhibited complete folding of consecutive human telomeric G-quadruplexes
EL Kristoffersen, A Coletta, LM Lund, B Schiøtt, V Birkedal
Nucleic Acids Research 51 (4), 1571-1582, 2023
Guanine-rich roadblocks for RECQ helicases
LM Lund, EL Kristoffersen, M Weiß, T Kulikowicz, VA Bohr, C Saintomé, ...
Biophysical Journal 123 (3), 500a, 2024
Transient Combustion Modeling for Hypergolic Engines
D Hoffpauir
Roles of dimeric intermediates in RNA-catalyzed rolling circle synthesis
EL Kristoffersen, E McRae, P Holliger, ES Andersen
bioRxiv, 2024.05. 14.594117, 2024
RecQ-helicase processing of G-rich DNA
LM Lund, EL Kristoffersen, T Kulikowicz, VA Bohr, V Birkedal
Biophysical Journal 121 (3), 210a, 2022
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