Zeta-potential data reliability of gold nanoparticle biomolecular conjugates and its application in sensitive quantification of surface absorbed protein W Wang, X Ding, Q Xu, J Wang, L Wang, X Lou Colloids and Surfaces B: Biointerfaces 148, 541-548, 2016 | 83 | 2016 |
Excision repair of topoisomerase DNA-protein crosslinks (TOP-DPC) Y Sun, S Saha, W Wang, LK Saha, SYN Huang, Y Pommier DNA repair 89, 102837, 2020 | 73 | 2020 |
Highly specific triple-fragment aptamer for optical detection of cocaine R Zou, X Lou, H Ou, Y Zhang, W Wang, M Yuan, M Guan, Z Luo, Y Liu RSC advances 2 (11), 4636-4638, 2012 | 48 | 2012 |
Kinetic adsorption profile and conformation evolution at the DNA-gold nanoparticle interface probed by dynamic light scattering W Wang, XF Ding, M He, J Wang, X Lou Analytical chemistry 86 (20), 10186-10192, 2014 | 41 | 2014 |
PARylation prevents the proteasomal degradation of topoisomerase I DNA-protein crosslinks and induces their deubiquitylation Y Sun, J Chen, SN Huang, YP Su, W Wang, K Agama, S Saha, ... Nature communications 12 (1), 5010, 2021 | 33 | 2021 |
Discovery of 4-alkoxy-2-aryl-6, 7-dimethoxyquinolines as a new class of topoisomerase I inhibitors endowed with potent in vitro anticancer activity MM Elbadawi, WM Eldehna, W Wang, KK Agama, Y Pommier, M Abe European journal of medicinal chemistry 215, 113261, 2021 | 29 | 2021 |
Recent Advances in Use of Topoisomerase Inhibitors in Combination Cancer Therapy W Wang, YC Tse-Dinh Current Topics in Medicinal Chemistry 19 (9), 730-740, 2019 | 26 | 2019 |
Evidence for inhibition of topoisomerase 1A by gold (III) macrocycles and chelates targeting Mycobacterium tuberculosis and Mycobacterium abscessus R Gupta, C Rodrigues Felix, MP Akerman, KJ Akerman, CA Slabber, ... Antimicrobial Agents and Chemotherapy 62 (5), 10.1128/aac. 01696-17, 2018 | 23 | 2018 |
Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites XZ Zhao, E Kiselev, GT Lountos, W Wang, JE Tropea, D Needle, ... Chemical Science 12 (11), 3876-3884, 2021 | 19 | 2021 |
Synthesis of methoxy-, methylenedioxy-, hydroxy-, and halo-substituted benzophenanthridinone derivatives as DNA topoisomerase IB (TOP1) and tyrosyl-DNA phosphodiesterase 1 … DX Hu, WL Tang, Y Zhang, H Yang, W Wang, K Agama, Y Pommier, ... Journal of medicinal chemistry 64 (11), 7617-7629, 2021 | 15 | 2021 |
The synthesis of furoquinolinedione and isoxazoloquinolinedione derivatives as selective Tyrosyl-DNA phosphodiesterase 2 (TDP2) inhibitors H Yang, XQ Zhu, W Wang, Y Chen, Z Hu, Y Zhang, DX Hu, LM Yu, ... Bioorganic chemistry 111, 104881, 2021 | 12 | 2021 |
Recifin A, initial example of the tyr-lock peptide structural family, is a selective allosteric inhibitor of tyrosyl-DNA phosphodiesterase I LRH Krumpe, BAP Wilson, C Marchand, SN Sunassee, A Bermingham, ... Journal of the American Chemical Society 142 (50), 21178-21188, 2020 | 7 | 2020 |
Tyrosyl-DNA phosphodiesterase 1 and topoisomerase I activities as predictive indicators for Glioblastoma susceptibility to genotoxic agents W Wang, M Rodriguez-Silva, AM Acanda de la Rocha, AL Wolf, Y Lai, ... Cancers 11 (10), 1416, 2019 | 6 | 2019 |
Mechanism and resistance for antimycobacterial activity of a fluoroquinophenoxazine compound PK Garcia, T Annamalai, W Wang, RS Bell, D Le, P Martin Pancorbo, ... Plos one 14 (2), e0207733, 2019 | 6 | 2019 |
Synthesis of 11-aminoalkoxy substituted benzophenanthridine derivatives as tyrosyl-DNA phosphodiesterase 1 inhibitors and their anticancer activity H Yang, FT Wang, M Wu, W Wang, K Agama, Y Pommier, LK An Bioorganic chemistry 123, 105789, 2022 | 4 | 2022 |
Synthesis and biological activities of 11‐and 12‐substituted benzophenanthridinone derivatives as DNA topoisomerase IB and tyrosyl‐DNA phosphodiesterase 1 inhibitors H Yang, C Qin, M Wu, FT Wang, W Wang, K Agama, Y Pommier, DX Hu, ... ChemMedChem 18 (10), e202200593, 2023 | 2 | 2023 |
Identification of multidentate tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitors that simultaneously access the DNA, protein and catalytic-binding sites by oxime diversification XZ Zhao, W Wang, GT Lountos, E Kiselev, JE Tropea, D Needle, ... RSC Chemical Biology 4 (5), 334-343, 2023 | 2 | 2023 |
Phosphonic Acid-containing Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 XZ Zhao, W Wang, GT Lountos, JE Tropea, D Needle, Y Pommier, ... Frontiers in Chemistry, 931, 2022 | 2 | 2022 |
Identification and characterization of topoisomerase III beta poisons W Wang, S Saha, X Yang, Y Pommier, SN Huang Proceedings of the National Academy of Sciences 120 (34), e2218483120, 2023 | 1 | 2023 |
Topoisomerase and Tyrosyl-DNA Phosphodiesterase Ratio as an Indicator for the Response of Glioblastoma Cancer to Topoisomerase Targeting Anticancer Drugs W Wang Florida International University, 2019 | | 2019 |