Cell encapsulation: promise and progress G Orive, RM Hernández, AR Gascón, R Calafiore, TMS Chang, PD Vos, ... Nature medicine 9 (1), 104-107, 2003 | 729 | 2003 |
History, challenges and perspectives of cell microencapsulation G Orive, RM Hernandez, AR Gascon, R Calafiore, TMS Chang, P De Vos, ... TRENDS in Biotechnology 22 (2), 87-92, 2004 | 463 | 2004 |
Delivery of human factor IX in mice by encapsulated recombinant myoblasts: a novel approach towards allogeneic gene therapy of hemophilia B G Hortelano, A Al-Hendy, FA Ofosu, PL Chang | 197 | 1996 |
Encapsulation of various recombinant mammalian cell types in different alginate microcapsules M Peirone, CJD Ross, G Hortelano, JL Brash, PL Chang Journal of Biomedical Materials Research: An Official Journal of The Society …, 1998 | 161 | 1998 |
Correction of the growth defect in dwarf mice with nonautologous microencapsulated myoblasts—an alternate approach to somatic gene therapy A Al-Hendy, G Hortelano, GS Tannenbaum, PL Chang Human Gene Therapy 6 (2), 165-175, 1995 | 129 | 1995 |
The in vivo delivery of heterologous proteins by microencapsulated recombinant cells PL Chang, JM Van Raamsdonk, G Hortelano, SC Barsoum, ... Trends in Biotechnology 17 (2), 78-83, 1999 | 112 | 1999 |
Cell encapsulation within alginate microcapsules: immunological challenges and outlook A Ashimova, S Yegorov, B Negmetzhanov, G Hortelano Frontiers in Bioengineering and Biotechnology 7, 380, 2019 | 101 | 2019 |
Growth of recombinant fibroblasts in alginate microcapsules PL Chang, G Hortelano, DE Awrey, M Tse Biotechnology and bioengineering 43 (10), 925-933, 1994 | 69 | 1994 |
Induction of angiogenesis by implantation of encapsulated primary myoblasts expressing vascular endothelial growth factor ML Springer, G Hortelano, DM Bouley, J Wong, PE Kraft, HM Blau The journal of gene medicine 2 (4), 279-288, 2000 | 67 | 2000 |
Permeability of alginate microcapsules to secretory recombinant gene products DE Awrey, M Tse, G Hortelano, PL Chang Biotechnology and Bioengineering 52 (4), 472-484, 1996 | 60 | 1996 |
Effects of genetic fusion of factor IX to albumin on in vivo clearance in mice and rabbits WP Sheffield, A Mamdani, G Hortelano, S Gataiance, L Eltringham‐Smith, ... British journal of haematology 126 (4), 565-573, 2004 | 58 | 2004 |
Delivery of a secretable adenosine deaminase through microcapsules–a novel approach to somatic gene therapy M Hughes, A Vassilakos, DW Andrews, G Hortelano, JW Belmont, ... Human Gene Therapy 5 (12), 1445-1455, 1994 | 58 | 1994 |
Persistent delivery of factor IX in mice: gene therapy for hemophilia using implantable microcapsules G Hortelano, N Xu, A Vandenberg, J Solera, PL Chang, FA Ofosu Human gene therapy 10 (8), 1281-1288, 1999 | 57 | 1999 |
Strategies for ocular siRNA delivery: Potential and limitations of non-viral nanocarriers A Thakur, S Fitzpatrick, A Zaman, K Kugathasan, B Muirhead, G Hortelano, ... Journal of biological engineering 6, 1-16, 2012 | 55 | 2012 |
Therapeutic levels of human factor VIII in mice implanted with encapsulated cells: potential for gene therapy of haemophilia A C García‐Martín, MKL Chuah, A Van Damme, KE Robinson, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2002 | 55 | 2002 |
Factors that contribute to the immmunogenicity of therapeutic recombinant human proteins I Mukovozov, T Sabljic, G Hortelano, FA Ofosu Thrombosis and haemostasis 99 (11), 874-882, 2008 | 53 | 2008 |
Reduction of GAG storage in MPS II mouse model following implantation of encapsulated recombinant myoblasts A Friso, R Tomanin, S Alba, N Gasparotto, EP Puicher, M Fusco, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005 | 49 | 2005 |
Repeated oral administration of chitosan/DNA nanoparticles delivers functional FVIII with the absence of antibodies in hemophilia A mice SS Dhadwar, J Kiernan, J Wen, G Hortelano Journal of Thrombosis and Haemostasis 8 (12), 2743-2750, 2010 | 47 | 2010 |
Sustained and therapeutic delivery of factor IX in nude haemophilia B mice by encapsulated C2C12 myoblasts: concurrent tumourigenesis G Hortelano, L Wang, N Xu, FA Ofosu Haemophilia 7 (2), 207-214, 2001 | 47 | 2001 |
Growth retardation—an unexpected outcome from growth hormone gene therapy in normal mice with microencapsulated myoblasts A Al-Hendy, G Hortelano, GS Tannenbaum, PL Chang Human Gene Therapy 7 (1), 61-70, 1996 | 43 | 1996 |