Quinoline derivatives bearing pyrazole moiety: Synthesis and biological evaluation as possible antibacterial and antifungal agents MF El Shehry, MM Ghorab, SY Abbas, EA Fayed, SA Shedid, YA Ammar European journal of medicinal chemistry 143, 1463-1473, 2018 | 190 | 2018 |
Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies SI Eissa, AM Farrag, SY Abbas, MF El Shehry, A Ragab, EA Fayed, ... Bioorganic Chemistry 110, 104803, 2021 | 81 | 2021 |
Antimicrobial evaluation of thiadiazino and thiazolo quinoxaline hybrids as potential DNA gyrase inhibitors; design, synthesis, characterization and morphological studies YA Ammar, AA Farag, AM Ali, SA Hessein, AA Askar, EA Fayed, DM Elsisi, ... Bioorganic Chemistry 99, 103841, 2020 | 61 | 2020 |
Design, synthesis, biological evaluation and molecular modeling of new coumarin derivatives as potent anticancer agents EA Fayed, R Sabour, MF Harras, ABM Mehany Medicinal Chemistry Research 28, 1284-1297, 2019 | 60 | 2019 |
In vitro cytotoxic activity of thiazole-indenoquinoxaline hybrids as apoptotic agents, design, synthesis, physicochemical and pharmacokinetic studies EA Fayed, YA Ammar, A Ragab, NA Gohar, ABM Mehany, AM Farrag Bioorganic Chemistry 100, 103951, 2020 | 47 | 2020 |
Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors EA Fayed, YA Ammar, MA Saleh, AH Bayoumi, A Belal, ABM Mehany, ... Journal of Molecular Structure 1236, 130317, 2021 | 46 | 2021 |
Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1, 2, 3-triazole-chalcone conjugates EM Othman, EA Fayed, EM Husseiny, HS Abulkhair Bioorganic Chemistry 123, 105762, 2022 | 43 | 2022 |
Hydrazonoyl bromide precursors as DHFR inhibitors for the synthesis of bis-thiazolyl pyrazole derivatives; antimicrobial activities, antibiofilm, and drug combination studies … SA Ibrahim, EA Fayed, HF Rizk, SE Desouky, A Ragab Bioorganic chemistry 116, 105339, 2021 | 43 | 2021 |
One-pot synthesis and molecular modeling studies of new bioactive spiro-oxindoles based on uracil derivatives as SARS-CoV-2 inhibitors targeting RNA polymerase and spike … SA El-Kalyoubi, A Ragab, OA Abu Ali, YA Ammar, MG Seadawy, A Ahmed, ... Pharmaceuticals 15 (3), 376, 2022 | 39 | 2022 |
In vivo screening and toxicity studies of indolinone incorporated thiosemicarbazone, thiazole and piperidinosulfonyl moieties as anticonvulsant agents EA Fayed, A Ragab, RRE Eldin, AH Bayoumi, YA Ammar Bioorganic Chemistry 116, 105300, 2021 | 39 | 2021 |
Isatin-Schiff’s base and chalcone hybrids as chemically apoptotic inducers and EGFR inhibitors; design, synthesis, anti-proliferative activities and in silico evaluation YAA Eman A. Fayed, Rogy R. Ezz Eldin, Ahmed B. M. Mehany, Ashraf H. Bayoumi Journal of Molecular Structure 1234, 130159, 2021 | 39 | 2021 |
One pot synthesis, antimicrobial and antioxidant activities of fused uracils: pyrimidodiazepines, lumazines, triazolouracil and xanthines SA El-Kalyoubi, EA Fayed, AS Abdel-Razek Chemistry Central Journal 11, 1-13, 2017 | 38 | 2017 |
Design, synthesis, cytotoxicity and molecular modeling studies of some novel fluorinated pyrazole-based heterocycles as anticancer and apoptosis-inducing agents EA Fayed, SI Eissa, AH Bayoumi, NA Gohar, ABM Mehany, YA Ammar Molecular diversity 23, 165-181, 2019 | 34 | 2019 |
Naproxen derivatives: synthesis, reactions, and biological applications YA Ammar, MA Salem, EA Fayed, MH Helal, MSA El-Gaby, HK Thabet Synthetic Communications 47 (15), 1341-1367, 2017 | 33 | 2017 |
Phenylthiazole antibiotics: A metabolism-guided approach to overcome short duration of action E Yahia, H Mohammad, TM Abdelghany, E Fayed, MN Seleem, ... European Journal of Medicinal Chemistry 126, 604-613, 2017 | 32 | 2017 |
In vitro antimicrobial evaluation and in silico studies of coumarin derivatives tagged with pyrano-pyridine and pyrano-pyrimidine moieties as DNA gyrase inhibitors EA Fayed, ES Nosseir, A Atef, SA El‑Kalyoubi Molecular Diversity, 1-23, 2021 | 29 | 2021 |
Novel cyclohepta [b] thiophene derivative incorporating pyrimidine, pyridine, and chromene moiety as potential antimicrobial agents targeting DNA gyrase EA Fayed, M Mohsen, SM Abd El-Gilil, DS Aboul-Magd, A Ragab Journal of Molecular Structure 1262, 133028, 2022 | 25 | 2022 |
Synthesis and evaluation of antitumour activities of novel fused tri-and tetracyclic uracil derivatives S ElKalyoubi, E Fayed Journal of Chemical Research 40 (12), 771-777, 2016 | 25 | 2016 |
Rationale design, synthesis, cytotoxicity evaluation, and in silico mechanistic studies of novel 1, 2, 3-triazoles with potential anticancer activity EM Othman, EA Fayed, EM Husseiny, HS Abulkhair New Journal of Chemistry 46 (25), 12206-12216, 2022 | 23 | 2022 |
Carboxamide appended quinoline moieties as potential anti-proliferative agents, apoptotic inducers and Pim-1 kinase inhibitors YA Ammar, GAM Elhagali, MS Abusaif, MR Selim, MA Zahran, T Naser, ... Medicinal Chemistry Research 30, 1649-1668, 2021 | 23 | 2021 |