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Atef A. Abdel-hafez
Atef A. Abdel-hafez
Professor of Medicinal Chemistry, Assuit University
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Transformation of arctiin to estrogenic and antiestrogenic substances by human intestinal bacteria
LH Xie, EM Ahn, T Akao, AAM Abdel-Hafez, N Nakamura, M Hattori
Chemical and pharmaceutical bulletin 51 (4), 378-384, 2003
1202003
Design, synthesis, and docking studies of new 1, 3, 4-thiadiazole-2-thione derivatives with carbonic anhydrase inhibitory activity
MK Abdel-Hamid, AA Abdel-Hafez, NA El-Koussi, NM Mahfouz, ...
Bioorganic & medicinal chemistry 15 (22), 6975-6984, 2007
1072007
Benzimidazole condensed ring systems: New synthesis and antineoplastic activity of substituted 3, 4-dihydro-and 1, 2, 3, 4-tetrahydro-benzo [4, 5] imidazo [1, 2-a] pyrinnidine …
AA Abdel-hafez
Archives of pharmacal research 30, 678-684, 2007
872007
Synthesis and anticonvulsant evaluation ofN-substituted-isoindolinedione derivatives
AAM Abdel-Hafez
Archives of pharmacal research 27, 495-501, 2004
692004
5-(4-Chlorophenyl)-5, 6-dihydro-1, 3-oxazepin-7 (4H)-one derivatives as lipophilic cyclic analogues of baclofen: Design, synthesis, and neuropharmacological evaluation
AA Abdel-Hafez, BA Abdel-Wahab
Bioorganic & medicinal chemistry 16 (17), 7983-7991, 2008
502008
Phytochemical Profiling, In Vitro and In Silico Anti-Microbial and Anti-Cancer Activity Evaluations and Staph GyraseB and h-TOP-IIβ Receptor-Docking Studies of Major …
HA Mohammed, RA Khan, AA Abdel-Hafez, M Abdel-Aziz, E Ahmed, ...
Molecules 26 (3), 577, 2021
452021
Chlorzoxazone esters of some non-steroidal anti-inflammatory (NSAI) carboxylic acids as mutual prodrugs: design, synthesis, pharmacological investigations and docking studies
AZ Abdel-Azeem, AA Abdel-Hafez, GS El-Karamany, HH Farag
Bioorganic & medicinal chemistry 17 (10), 3665-3670, 2009
402009
Anticonvulsant activity of paeonimetabolin-I adducts obtained by incubation of paeoniflorin and thiol compounds with Lactobacillus brevis
AA Abdel-Hafez, MR Meselhy, N Nakamura, M Hattori, H Watanabe, ...
Biological and Pharmaceutical Bulletin 22 (5), 491-497, 1999
381999
Phenylthiomethyl ketone-based fragments show selective and irreversible inhibition of enteroviral 3C proteases
R Schulz, A Atef, D Becker, F Gottschalk, C Tauber, S Wagner, C Arkona, ...
Journal of Medicinal Chemistry 61 (3), 1218-1230, 2018
262018
Potent anticonvulsant paeonimetabolin-I derivatives obtained by incubation of paeoniflorin and thiol compounds with Lactobacillus brevis
AA Abdel-Hafez, MR Meselhy, N Nakamura, M Hattori, H Watanabe, ...
Chemical and pharmaceutical bulletin 46 (9), 1486-1487, 1998
251998
Potent anticonvulsant paeonimetabolin-I derivatives obtained by incubation of paeoniflorin and thiol compounds with Lactobacillus brevis
AA Abdel-Hafez, MR Meselhy, N Nakamura, M Hattori, H Watanabe, ...
Chemical and pharmaceutical bulletin 46 (9), 1486-1487, 1998
251998
Effects of paeoniflorin derivatives on scopolamine-induced amnesia using a passive avoidance task in mice; structure-activity relationship
AA Abdel-Hafez, MR MEsELHY, N Nakamura, M HATToRI, H Watanabe, ...
Biological and Pharmaceutical Bulletin 21 (11), 1174-1179, 1998
241998
Synthesis and evaluation of anti-HIV-1 and anti-HSV-1 activities of 4H-[1, 2, 4]-triazolo [1, 5-a] pyrimidin-5-one derivatives
AA Abdel-Hafez, HAH Elsherief, M Jo, M Kurokawa, K Shiraki, ...
Arzneimittelforschung 52 (11), 833-839, 2002
232002
Biotransformation of phorbol by human intestinal bacteria
AAM Abdel-Hafez, N Nakamura, M Hattori
Chemical and pharmaceutical bulletin 50 (2), 160-164, 2002
172002
The Anti-Inflammatory Effect of a γ-Lactone Isolated from Ostrich Oil of Struthio camelus (Ratite) and Its Formulated Nano-Emulsion in Formalin-Induced Paw Edema
SEM Eltom, AAH Abdellatif, H Maswadeh, MS Al-Omar, AA Abdel-Hafez, ...
Molecules 26 (12), 3701, 2021
162021
Inhibition of cytopathic effect of human immunodeficiency virus type-1 by various phorbol derivatives
S El-Mekkawy, MR Meselhy, AAM Abdel-Hafez, N Nakamura, M Hattori, ...
Chemical and pharmaceutical bulletin 50 (4), 523-529, 2002
162002
Microemulsion for ocular delivery: Ocular irritancy test and in vivo studies of anti-inflammatory action
F Habib, M El-Mahdy, A Abdel-Hafez, S Maher
Journal of drug delivery science and technology 22 (6), 541-544, 2012
142012
Quantitative structure–activity relationship (QSAR) studies on a series of 1, 3, 4-thiadiazole-2-thione derivatives as tumor-associated carbonic anhydrase IX inhibitors
MK Abdel-Hamid, AA Abdel-Hafez, NA El-Koussi, NM Mahfouz
Journal of Enzyme Inhibition and Medicinal Chemistry 24 (3), 722-729, 2009
92009
Design, synthesis, and cytotoxicity evaluation of novel griseofulvin analogues with improved water solubility
AK Hamdy, MM Sheha, AA Abdel-Hafez, SA Shouman
International Journal of Medicinal Chemistry 2017, 2017
72017
Comparative study for brain delivery of tacrine using polysorbate 80-coated poly (butylcyanoacrylate) and pegylated-poly (butylcyanoacrylate) nanoparticles
BA Abdel-Wahab, MM Abdel-Latif, AA Abdel-Hafez
International Journal of Nano and Biomaterials 2 (1-5), 360-374, 2009
72009
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