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Alaa A.-M. Abdel-Aziz PhD
Alaa A.-M. Abdel-Aziz PhD
King Saud University, Mansoura University, Kumamoto University
Verified email at ksu.edu.sa
Title
Cited by
Cited by
Year
Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: molecular docking study
AS El-Azab, MA Al-Omar, AM Alaa, NI Abdel-Aziz, AA Magda, AM Aleisa, ...
European journal of medicinal chemistry 45 (9), 4188-4198, 2010
2862010
Synthesis, dihydrofolate reductase inhibition, antitumor testing, and molecular modeling study of some new 4 (3H)-quinazolinone analogs
ST Al-Rashood, IA Aboldahab, MN Nagi, LA Abouzeid, AAM Abdel-Aziz, ...
Bioorganic & medicinal chemistry 14 (24), 8608-8621, 2006
2402006
Substituted quinazolines, part 3. Synthesis, in vitro antitumor activity and molecular modeling study of certain 2-thieno-4 (3H)-quinazolinone analogs
AM Al-Obaid, SG Abdel-Hamide, HA El-Kashef, AM Alaa, AS El-Azab, ...
European journal of medicinal chemistry 44 (6), 2379-2391, 2009
2232009
Novel and versatile methodology for synthesis of cyclic imides and evaluation of their cytotoxic, DNA binding, apoptotic inducing activities and molecular modeling study
AM Alaa
European journal of medicinal chemistry 42 (5), 614-626, 2007
1932007
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, YA Asiri, KEH ElTahir
Bioorganic & medicinal chemistry 19 (11), 3416-3424, 2011
1802011
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2
AA Magda, NI Abdel-Aziz, AM Alaa, AS El-Azab, KEH ElTahir
Bioorganic & medicinal chemistry 20 (10), 3306-3316, 2012
1712012
Non-classical antifolates. Part 2: synthesis, biological evaluation, and molecular modeling study of some new 2, 6-substituted-quinazolin-4-ones
FAM Al-Omary, LA Abou-Zeid, MN Nagi, ESE Habib, AM Alaa, AS El-Azab, ...
Bioorganic & medicinal chemistry 18 (8), 2849-2863, 2010
1622010
Synthesis, antimicrobial activity and conformational analysis of novel substituted pyridines: BF3-promoted reaction of hydrazine with 2-alkoxy pyridines
FE Goda, AM Alaa, OA Attef
Bioorganic & medicinal chemistry 12 (8), 1845-1852, 2004
1532004
Structure-based design of phthalimide derivatives as potential cyclooxygenase-2 (COX-2) inhibitors: anti-inflammatory and analgesic activities
AM Alanazi, AS El-Azab, IA Al-Suwaidan, KEH ElTahir, YA Asiri, ...
European journal of medicinal chemistry 92, 115-123, 2015
1302015
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study
AM Alaa, KEH ElTahir, YA Asiri
European journal of medicinal chemistry 46 (5), 1648-1655, 2011
1192011
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibitory activities and molecular docking studies of substituted 2-mercapto-4 (3H)-quinazolinones
AM Alaa, LA Abou-Zeid, KEH ElTahir, RR Ayyad, AA Magda, AS El-Azab
European Journal of Medicinal Chemistry 121, 410-421, 2016
992016
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis [N-(2, 6-diisopropylphenyl) imino] acenaphthene
U El-Ayaan, AM Alaa
European journal of medicinal chemistry 40 (12), 1214-1221, 2005
922005
Synthesis and antitumor evaluation of trimethoxyanilides based on 4 (3H)-quinazolinone scaffolds
MA Mohamed, RR Ayyad, TZ Shawer, AM Alaa, AS El-Azab
European journal of medicinal chemistry 112, 106-113, 2016
902016
Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment
AH El-Kamel, AM Alaa, AJ Fatani, HI El-Subbagh
International journal of pharmaceutics 358 (1-2), 248-255, 2008
872008
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation
AM Alaa, HI El-Subbagh, T Kunieda
Bioorganic & medicinal chemistry 13 (16), 4929-4935, 2005
822005
Synthesis, anti-inflammatory, analgesic, COX-1/2 inhibition activities and molecular docking study of pyrazoline derivatives
MA Abdel-Sayed, SM Bayomi, MA El-Sherbeny, NI Abdel-Aziz, ...
Bioorganic & Medicinal Chemistry 24 (9), 2032-2042, 2016
812016
Design, synthesis of 2, 3-disubstitued 4 (3H)-quinazolinone derivatives as anti-inflammatory and analgesic agents: COX-1/2 inhibitory activities and molecular docking studies
AM Alaa, LA Abou-Zeid, KEH ElTahir, MA Mohamed, MAA El-Enin, ...
Bioorganic & Medicinal Chemistry 24 (16), 3818-3828, 2016
762016
Synthesis and antitumor evaluation of novel cyclic arylsulfonylureas: ADME-T and pharmacophore prediction
IM El-Deeb, SM Bayoumi, MA El-Sherbeny, AM Alaa
European journal of medicinal chemistry 45 (6), 2516-2530, 2010
762010
Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4 (3H) quinazolinone analogues
IA Al-Suwaidan, AAM Abdel-Aziz, TZ Shawer, RR Ayyad, AM Alanazi, ...
Journal of enzyme inhibition and medicinal chemistry 31 (1), 78-89, 2016
752016
Design, synthesis and antibacterial activity of fluoroquinolones containing bulky arenesulfonyl fragment: 2D-QSAR and docking study
AM Alaa, YA Asiri, MHM Al-Agamy
European journal of medicinal chemistry 46 (11), 5487-5497, 2011
752011
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